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      • KCI등재

        Oral rehabilitation of Papillon-Lefèvre syndrome patients by dental implants: a systematic review

        Fazele Atarbashi-Moghadam,Saede Atarbashi-Moghadam,Setare Kazemifard,Soran Sijanivandi,Mahshid Namdari 대한구강악안면외과학회 2020 대한구강악안면외과학회지 Vol.46 No.4

        Objectives: Papillon-Lefèvre syndrome (PLS) is a rare autosomal recessive disorder. These patients lose their teeth at a young age and are in need of prosthetic rehabilitation. The aim of this systematic review was to assess the success of dental implant placement in these patients. Materials and Methods: An electronic search was performed in PubMed Central, Scopus, and Web of Science using the keyword “Papillon-Lefèvre syndrome” AND “dental implant” OR “prosthodontics”. Articles reporting implant placement in patients with PLS until July 2019 were included. Results: Assessment of the included 11 articles reporting 15 cases showed 136 implant placements in these patients. Implant failure occurred in 3 patients (20 implants). The peri-implantitis and failure rate was higher in the maxilla. Meta-analysis showed the probability of failure to be 7% (95% confidence interval [CI] 0%-31%) for maxillary implants and 2% (95% CI 0%-9%) for mandibular implants. The follow-up time ranged between 1 and 20 years. Healing after bone graft and implant placement in these patients was uneventful. Conclusion: Dental implants may be a viable treatment option for PLS patients. Implantation can help preserve alveolar bone if the patients’ immunological and growing conditions are well-considered and proper oral hygiene and compliance with the maintenance program are continued.

      • KCI등재

        Prevalence and Predictive Factors of Sexual Dysfunction in Iranian Women: Univariate and Multivariate Logistic Regression Analyses

        Ashraf Direkvand-Moghadam,Zainab Suhrabi,Malihe Akbari,Azadeh Direkvand-Moghadam 대한가정의학회 2016 Korean Journal of Family Medicine Vol.37 No.5

        Background: Female sexual dysfunction, which can occur during any stage of a normal sexual activity, is a serious condition for individuals and couples. The present study aimed to determine the prevalence and predictive factors of female sexual dysfunction in women referred to health centers in Ilam, the Western Iran, in 2014.Methods: In the present cross-sectional study, 444 women who attended health centers in Ilam were enrolled from May to September 2014. Participants were selected according to the simple random sampling method. Univariate and multivariate logistic regression analyses were used to predict the risk factors of female sexual dysfunction. Diffe rences with an alpha error of 0.05 were regarded as statistically significant.Results: Overall, 75.9% of the study population exhibited sexual dysfunction. Univariate logistic regression analysis demonstrated that there was a significant association between female sexual dysfunction and age, menarche age, gravidity, parity, and education (P<0.05). Multivariate logistic regression analysis indicated that, menarche age (odds ratio, 1.26), education level (odds ratio, 1.71), and gravida (odds ratio, 1.59) were independent predictive vari-ables for female sexual dysfunction.Conclusion: The majority of Iranian women suffer from sexual dysfunction. A lack of awareness of Iranian women’s sexual pleasure and formal training on sexual function and its influencing factors, such as menarche age, gravida, and level of education, may lead to a high prevalence of female sexual dysfunction.

      • SCOPUSKCI등재
      • SCOPUSKCI등재

        Comparative Study of Various Persian Stemmers in the Field of Information Retrieval

        Moghadam, Fatemeh Momenipour,Keyvanpour, MohammadReza Korea Information Processing Society 2015 Journal of information processing systems Vol.11 No.3

        In linguistics, stemming is the operation of reducing words to their more general form, which is called the 'stem'. Stemming is an important step in information retrieval systems, natural language processing, and text mining. Information retrieval systems are evaluated by metrics like precision and recall and the fundamental superiority of an information retrieval system over another one is measured by them. Stemmers decrease the indexed file, increase the speed of information retrieval systems, and improve the performance of these systems by boosting precision and recall. There are few Persian stemmers and most of them work based on morphological rules. In this paper we carefully study Persian stemmers, which are classified into three main classes: structural stemmers, lookup table stemmers, and statistical stemmers. We describe the algorithms of each class carefully and present the weaknesses and strengths of each Persian stemmer. We also propose some metrics to compare and evaluate each stemmer by them.

      • SCOPUSKCI등재

        Effects of Oleo Gum Resin of Ferula assa-foetida L. on Senescence in Human Dermal Fibroblasts - Asafoetida reverses senescence in fibroblasts -

        Moghadam, Farshad Homayouni,Mesbah-Ardakani, Mehrnaz,Nasr-Esfahani, Mohammad Hossein KOREAN PHARMACOPUNCTURE INSTITUTE 2017 Journal of pharmacopuncture Vol.20 No.3

        Objectives: Based on data from Chinese and Indian traditional herbal medicines, gum resin of Ferula assa-foetida (sometimes referred to asafetida or asafoetida) has several therapeutic applications. The authors of various studies have claimed that asafetida has cytotoxic, antiulcer, anti-neoplasm, anti-cancer, and anti-oxidative effects. In present study, the anti-aging effect of asafetida on senescent human dermal fibroblasts was evaluated. Methods: Senescence was induced in in vitro cultured human dermal fibroblasts (HDFs) through exposure to $H_2O_2$, and the incidence of senescence was recognized by using cytochemical staining for the activity of ${\beta}$-galactosidase. Then, treatment with oleo gum resin of asafetida was started to evaluate its rejuvenating effect. The survival rate of fibroblasts was evaluated by using methyl tetrazolium bromide (MTT) assays. Real-time quantitative reverse transcription-polymerase chain reaction (qRT-PCR) and western blot assays were performed to evaluate the expressions of apoptotic and anti-apoptotic markers. Results: Our experiments show that asafetida in concentrations ranging from $5{\times}10^{-8}$ to $10^{-7}g/mL$ has revitalizing effects on senescent fibroblasts and significantly reduces the ${\beta}$-galactosidase activity in these cells (P < 0.05). Likewise, treatment at these concentrations increases the proliferation rate of normal fibroblasts (P < 0.05). However, at concentrations higher than $5{\times}10^{-7}g/mL$, asafetida is toxic for cells and induces cell death. Conclusion: The results of this study indicate that asafetida at low concentrations has a rejuvenating effect on senescent fibroblasts whereas at higher concentrations, it has the opposite effect of facilitating cellular apoptosis and death.

      • KCI등재

        Sleep Disorders During Pregnancy and Postpartum: A Systematic Review

        Moghadam Zahra Behboodi,Rezaei Elham,Rahmani Azam 대한수면학회 2021 sleep medicine research Vol.12 No.2

        This study aimed to asses previous research results about bio-physiological alterations during pregnancy and postpartum, and make clear outlook about prevalence and related factors of sleep disorders during pregnancy and postpartum. In this review, the articles that published from 2000 to 2019 were reviewed. Related articles were searched from databases in English language. After evaluation of inclusion and exclusion criteria, articles were chosen and reviewed based on the University of York strategies. Sleep disorders in present study were classified according to the International Classification of Sleep Disorders-3. The search revealed 4449 articles, after evaluating and assessing qualified articles, finally 56 article selected to review. According to the results of this review, The prevalence of sleep disorders was almost 76%–97% in whole pregnancy. The most common sleep disorders included central disorders of hyper somnolence (waking up in the middle of the night, daytime sleepiness, sleeplessness) or insomnia, sleep-related movement disorders (restless legs syndrome), sleep related breathing disorders (obstructive sleep apnea), and parasomnia. In addition, sleep disorder may continue 3–12 months postpartum (33.2%). Sleep disorders induced by physiological processes (fetal movement, excessive weight gain, male sex of the fetus, and multiparty), health-related risks (metabolism disorders, cardiovascular diseases, and mood disorders), and physical or sexual abuse in childhood. In addition, these disorders could have maternal outcomes that can be greatest trigger to postpartum psychiatric disorders and fetal outcomes that have harmful sequences during childhood (sexual, fertility, emotional, and cognitive problems). Health care providers should evaluate the mothers’ sleep quality because sleep disorder leads to harmful consequences in fetuses and children.

      • Two-dimensional materials: an emerging platform for gas separation membranes

        Moghadam, Farhad,Park, Ho Bum Elsevier 2018 Current opinion in chemical engineering Vol.20 No.-

        <P>Graphene and its derivatives are of particular interest as emerging platforms for molecular separation. However, there are abundant 2D nanomaterials other than graphene that have unique and intriguing structural features that can be exploited for membrane-based separation that have not been extensively studied. Furthermore, from a materials synthesis standpoint, realizing high yield and scalable methods for massive production of 2D nanomaterials is critical. Liquid-based exfoliation to produce 2D nanosheets from layered bulk crystals has recently drawn considerable attention. Such single-layered or few-layered 2D nanosheets can be formed into laminate membranes with exceptional molecular-sieving properties or more preferably utilized as high aspect ratio nanofillers to improve the separation performance of polymer membranes. Most remarkably, 2D nanosheets can mitigate the well-known plasticization phenomenon in polymer membranes by interacting strongly with the polymer chains. There is no doubt that these emerging 2D nanomaterials will facilitate fabrication of next-generation membranes.</P> <P><B>Highlights</B></P> <P> <UL> <LI> There are abundant 2D materials beyond graphene for gas separation membranes. </LI> <LI> Liquid exfoliation showed great promise for scalable production of 2D materials. </LI> <LI> 2D materials-based mixed matrix membranes have shown great promise for gas separation. </LI> <LI> 2D materials play a unique role to mitigate the plasticization of polymer membranes. </LI> </UL> </P>

      • SCOPUSKCI등재

        Association between Dietary Acid Load and Insulin Resistance: Tehran Lipid and Glucose Study

        Moghadam, Sajjad Khalili,Bahadoran, Zahra,Mirmiran, Parvin,Tohidi, Maryam,Azizi, Fereidoun The Korean Society of Food Science and Nutrition 2016 Preventive Nutrition and Food Science Vol.21 No.2

        In the current study, we investigated the longitudinal association between dietary acid load and the risk of insulin resistance (IR) in the Tehranian adult population. This longitudinal study was conducted on 925 participants, aged 22~80 years old, in the framework of the third (2006~2008) and fourth (2009~2011) phases of the Tehran Lipid and Glucose Study. At baseline, the dietary intake of subjects was assessed using a validated semi-quantitative food frequency questionnaire, and the potential renal acid load (PRAL) and net endogenous acid production (NEAP) scores were calculated at baseline. Fasting serum insulin and glucose were measured at baseline and again after a 3-year of follow-up; IR was defined according to optimal cut-off values. Multiple logistic regression models were used to estimate the risk of IR according to the PRAL and NEAP quartile categories. Mean age and body mass index of the participants were 40.3 years old of $26.4kg/m^2$, respectively. Mean PRAL and NEAP scores were -11.2 and 35.6 mEq/d, respectively. After adjustment for potential confounders, compared to the lowest quartile of PRAL and NEAP, the highest quartile was accompanied with increased risk of IR [odds ratio (OR)=2.81, 95% confidence interval (CI)=1.32~5.97 and OR=2.18, 95% CI=1.03~4.61, respectively]. Our findings suggest that higher acidic dietary acid-base load, defined by higher PRAL and NEAP scores, may be a risk factor for the development of IR and related metabolic disorders.

      • KCI등재
      • KCI등재

        Effects of Platelet-Rich Plasma on Kidney Regeneration in Gentamicin-Induced Nephrotoxicity

        Abbas Moghadam,,Tahereh Talaei-Khozani,Afsaneh Mafi,Mohammad Reza Namavar,Farzaneh Dehghani 대한의학회 2017 Journal of Korean medical science Vol.32 No.1

        Platelet-rich plasma (PRP) as a source of growth factors may induce tissue repairing and improve fibrosis. This study aimed to assess the effects of PRP on kidney regeneration and fibrosis in gentamicin (GM)-induced nephrotoxicity rat model by stereological study. Thirty-two male rats were selected. Nephrotoxicity was induced in animals by administration of GM (80 mg/kg/daily, intraperitoneally [IP], 8 day) and animals were treated by PRP (100 µL, intra-cortical injection using surgical microscopy, single dose). Blood samples were collected for determine blood urea nitrogen (BUN) and creatinine (Cr) before and after PRP therapy. At the end of experiment, right kidneys were sectioned by Isotropic Uniform Random (IUR) method and stained with H & E and Masson’s Trichrome. The stereological methods were used for estimating the changes in different structures of kidney. PRP increased the number of epithelial cells in convoluted tubules, and decreased the volume of connective tissue, renal corpuscles and glomeruli in GM-treated animals (P < 0.05). Our findings indicate that PRP had beneficial effects on proliferation of epithelial cells in convoluted tubules and ameliorated GM-induced fibrosis.

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