Suppression of Mechanical Resonance Using Torque Disturbance Observer for Two-Inertia System with Backlash

Ming Yang,Weilong Zheng,Kaixuan Yang,Dianguo Xu 전력전자학회 2015 ICPE(ISPE)논문집 Vol.2015 No.6

In servo system, elastic component in transmission can produce mechanical resonance. The existence of backlash will aggravate the damage of resonance. According to dead-zone model, two-mass elastic system with backlash is established. The conclusion that the existence of backlash decreases the elastic coefficient of shaft equivalently and its quantitative relation are researched. This paper proposes a torque disturbance observer to realize the suppression of mechanical resonance with limiting control for shaft torque amplitude. The observer can decrease ratio of inertia equivalently in the case of no identification of backlash value. It has a compensation result that system is changed to a rigid system with single moment of inertia. In addition, this compensation algorithm is independent with parameters and configuration of speed controller. Simulations and experiments demonstrate the effectiveness of this torque disturbance observer.

Multivariate Analysis of the Prognosis of 37 Chondrosarcoma Patients

Yang, Zheng-Ming,Tao, Hui-Min,Ye, Zhao-Ming,Li, Wei-Xu,Lin, Nong,Yang, Di-Sheng Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.4

Objective: The current study aimedto screen for possible factors which affect prognosis of chondrosarcoma. Methods: Thirty seven cases were selected and analyzed statistically. The patients received surgical treatment at our hospital between December 2005 and March 2008. All of them had complete follow-up data. The survival rates were calculated by univariate analysis using the Kaplan-Meier method and tested by Log-rank. ${\chi}^2$ or Fisher exact tests were carried out for the numeration data. The significant indexes after univariate analysis were then analyzed by multivariate analysis using COX regression model. Based on the literature, factors of gender, age, disease course, tumor location, Enneking grades, surgical approaches, distant metastasis and local recurrence were examined. Results: Univariate analysis showed that there were significant differences in Enneking grades, surgical approaches and distant metastasis related to the patients' 3-year survival rate after surgery (P<0.001). No significant difference was not found in gender, age, disease course, tumor location or local recurrence (P>0.05). Multivariate analysis showed that Enneking grade (P=0.007) and surgical approaches (P=0.010) were independent factors affecting the prognosis of chondrosarcoma, but distant metastasis was not (P=0.942). Conclusion: Enneking grades, surgical approaches and distant metastasis are risk factors for prognosis of chondrosarcoma, among which the former two are independent factors.

Resource Allocation based on Quantized Feedback for TDMA Wireless Mesh Networks

Xu, Lei,Tang, Zhen-Min,Li, Ya-Ping,Yang, Yu-Wang,Lan, Shao-Hua,Lv, Tong-Ming The Institute of Electronics and Information Engin 2013 IEIE Transactions on Smart Processing & Computing Vol.2 No.3

Resource allocation based on quantized feedback plays a critical role in wireless mesh networks with a time division multiple access (TDMA) physical layer. In this study, a resource allocation problem was formulated based on quantized feedback for TDMA wireless mesh networks that minimize the total transmission power. Three steps were taken to solve the optimization problem. In the first step, the codebook of the power, rate and equivalent channel quantization threshold was designed. In the second step, the timeslot allocation criterion was deduced using the primal-dual method. In the third step, a resource allocation scheme was developed based on quantized feedback using the stochastic optimization tool. The simulation results show that the proposed scheme not only reduces the total transmission power, but also has the advantage of quantized feedback.

Research on Flame Retardant Plywood with Different Flame Retardants

( Yang Liu ),( Jun-xian Xu ),( Ming-yu Wen ),( Hee-jun Park ),( Jia-zhi Zhu ),( Yu-nan Liu ) 한국목재공학회 2021 목재공학 Vol.49 No.6

The flame retardancy of plywood should be improved as much as possible while minimizing the impact on the bonding strength of plywood. Six commercial flame retardants and three laboratory synthesized phosphorous nitrogen flame retardants were selected. E₀, E₁ and E₂ grade commercial formaldehyde resins (UF) were applied in this study to evaluate the effect of different flame retardants on the curing time of resin, bonding strength, flame retardant performance, and formaldehyde emission of plywood. The results show that the effect of the addition of different flame retardants on the bonding strength of plywood gradually decreased with the increase of the formaldehyde molar ratio of the resin. The effect of flame retardants on the curing time of UF gradually decreased as the mole ratio of formaldehyde increasing, while the amount of formaldehyde emission varied according to the content of formaldehyde in the flame retardant. Compared with plywood without flame retardant, flame retardant of plywood added with phosphorous nitrogen flame retardant was improved.

Estrogen Receptor α Roles in Breast Cancer Chemoresistance

Xu, Chao-Yang,Jiang, Zhi-Nong,Zhou, Ying,Li, Jia-Jia,Huang, Li-Ming Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.7

Resistance to chemotherapy treatment, which may lead to limited efficacy of systemic therapy in breast cancer patients, is multifactorial. Among the mechanisms of resistance to chemotherapy treatment, there are those closely related to estrogen receptor ${\alpha}$, P-glycoprotein, multidrug resistance-related protein, glutathione S-transferase pi and topoisomerase-II. $ER{\alpha}$ is ligand-activated transcription factor that regulates gene expression and plays a critical role in endocrine signaling. In previous preclinical and clinical studies, positive $ER{\alpha}$ expression in breast cancer cells was correlated with decreased sensitivity to chemotherapy. This article reviews current knowledge on the predictive value of $ER{\alpha}$ with regard to response to chemotherapy. Better understanding of its role may facilitate patient selection of therapeutic regimens and lead to optimal clinical outcomes.

IL-6-6331 (T/C, rs10499563) is Associated with Decreased Risk of Gastric Cancer in Northern Chinese

Yang, Li,Sun, Ming-Jun,Liu, Jing-Wei,Xu, Qian,Yuan, Yuan Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.12

Background: Polymorphisms of genes encoding cytokines could be potential biomarkers to predict risk of gastric cancer (GC). Here, we investigated the association between the IL-6 -6331 (T/C, rs10499563) polymorphism in its promoter region and GC risk. Methods: In this case-control study of 215 GC cases and 518 non-cancer controls, the IL-6 -6331 (T/C, rs10499563) polymorphism was genotyped by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Results: Individuals with the TC or CC genotype were associated with a significantly decreased risk of GC (OR=0.710, 95%CI: 0.504-0.999, P=0.049) compared with TT wild-type carriers. Ther C allele was also associated with significantly decreased risk of GC (OR=0.715, 95%CI: 0.536-0.954, P=0.023) compared with the T allele. In the stratification analysis, TC or CC genotypes were associated with significantly decreased GC risk in subgroups of males, people older than 60, and H. pylori-positive cases. However, no significant interaction was observed for TC or CC genotypes with H. pylori infection. On stratification with the Lauren classification, TC or CC genotypes were associated with significantly decreased risk of diffuse-type GC (OR=0.497, 95%CI: 0.266-0.925, P=0.027), also in subgroups of males, people older than 60, and H. pylori-positive cases. Conclusions: The IL-6 -6331 (T/C, rs10499563) polymorphism is associated with genetic susceptibility of GC and may have the potential to predict GC risk.

Double Modification of Electrode Surface for the Selective Detection of Epinephrine and Its Application to Flow Injection Amperometric Analysis

Xu, Guang-Ri,Qi, Xin-hua,Yang, Fengxia,Lee, Jae-Joon,Xu, Ming-Lu,Zhang, Yu-Ping,Kim, Sunghyun WILEY-VCH Verlag 2009 Electroanalysis Vol.21 No.22

<P>A glassy carbon electrode having two polymer layers has been applied to selectively detect epinephrine. The inner layer formed by electropolymerization of macrocyclic nickel complex functioned as an electrocatalyst for epinephrine oxidation and the outer layer composed of hydrolyzed polyurethane γ-benzyl L-glutamate as a screening layer. Differential pulse voltammetry showed almost 100% recovery of epinephrine even in 100-fold excess of interferents. When applied to a dual glassy carbon electrode as an amperometric detector in flow injection analysis, a linear response over 0.1 μM and 10 μM was obtained. Recovery tested for 5-fold diluted human urine samples was 97.5%.</P>

Molecular Characterization of A Novel Bacillus thuringiensis Strain from China

( Xu Feng Qi ),( Ming Shun Li ),( Jae Young Choi ),( Yang Su Kim ),( Yong Wang ),( Joong Nam Kang ),( Hee Kyu Choi ),( Yeon Ho Je ),( Ji Zhen Song ),( Jian Hong Li ) 한국잠사학회 2005 International Journal of Industrial Entomology Vol.11 No.1

A strain of Bacillus thuringiensis that showed significantly high toxicity to Plutella xylostella was isolated from a dust sample collected from Chinese tobacco warehouse and characterized. The isolate named B. thuringiensis LY-99 was determined to belong to subsp. alesti (H3a3c) by an H antisera agglutination test and produced bipyramidal inclusions. Plasmid and crystal protein patterns of the LY-99 were different from those of the reference strain, subsp. alesti. PCR analysis with specific primers revealed that this isolate contained abundant cry genes including cry1Aa, cry1Ac, cry1B, cry1D, cry1E, cry1F and cry2 genes, which was absolutely different from cry gene profile of the subsp. alesti. In addition, insecticidal activity of the LY-99 against P. xylostella larvae was about 44 times higher than that of the subsp. alesti.

Is Hepatectomy for Huge Hepatocellular Carcinoma (≥10cm in Diameter) Safe and Effective? A Single-center Experience

Yang, Jian,Li, Chuan,Wen, Tian-Fu,Yan, Lu-Nan,Li, Bo,Wang, Wen-Tao,Yang, Jia-Yin,Xu, Ming-Qing Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.17

Background: This retrospective study aimed to validate the safety and effectiveness of hepatectomy for huge hepatocellular carcinoma (HCC). Materials and Methods: Data of patients who underwent hepatectomy for HCC between January 2006 and December 2012 were reviewed. The patients were divided into three groups: huge HCC(${\geq}10cm$ in diameter), large HCC(${\geq}5$ but<10 cm in diameter) and small HCC(<5cm in diameter). Results: Characteristics of pre-operative patients in all three groups were homogeneously distributed except for alpha fetal protein (AFP)(p<0.001).The 30, 60, 90-day post-operative mortality rates were not different among the three groups (p=0.785, p=0.560, and p=0.549). Laboratory data at 1, 3, and 7 days after surgery also did not vary. The 5-year overall survival (OS) and 5-year disease-free survival (DFS) rates in the huge and large HCC groups were lower than that of the small HCC group (OS: 32.5% vs 36.3% vs 71.2%, p=0.000; DFS: 20.0% vs 24.8% vs 40.7%, p=0.039), but there was no difference between the huge and large HCC groups (OS: 32.5% vs 36.3%, p=0.667; DFS: 20.0% vs 24.8%, p=0.540). In multivariate analysis, five independent poor prognostic factors that affected OS were significantly associated with worse survival (p<0.05), namely, AFP level, macrovascular invasion, Edmondsone Steiner grade, surgical margin and Ishak score. AFP level, macrovascular invasion, microvascular invasion, and surgical margin influenced disease-free survival independently (p<0.05). Conclusions: The safety of hepatectomy for huge HCC is similar to that for large and small HCC; and this approach for huge HCC may achieve similar long-term survival and disease-free survival as for large HCC.

The Role of Gut Microbiota and Genetic Susceptibility in the Pathogenesis of Pancreatitis

Xu Fumin,Yang Chunmei,Tang Mingcheng,Wang Ming,Cheng Zhenhao,Chen Dongfeng,Chen Xiao,Liu Kaijun 거트앤리버 소화기연관학회협의회 2022 Gut and Liver Vol.16 No.5

Pancreatitis is one of the most common inflammatory diseases of the pancreas caused by autodigestion induced by excessive premature protease activation. However, recognition of novel pathophysiological mechanisms remains a still challenge. Both genetic and environmental factors contribute to the pathogenesis of pancreatitis, and the gut microbiota is a potential source of an environmental effect. In recent years, several new frontiers in gut microbiota and genetic risk assessment research have emerged and improved the understanding of the disease. These investigations showed that the disease progression of pancreatitis could be regulated by the gut microbiome, either through a translocation influence or in a host immune response manner. Meanwhile, the onset of the disease is also associated with the heritage of a pathogenic mutation, and the disease progression could be modified by genetic risk factors. In this review, we focused on the recent advances in the role of gut microbiota in the pathogenesis of pancreatitis, and the genetic susceptibility in pancreatitis.