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      • KCI등재

        Validity and Reliability of Metacognitive Rating Scale for Nursing Students

        ( Lee¸ Kyunghee ),( Heo¸ Youngjin ),( Han¸ Mihwa ),( Kim¸ Mijung ),( Choi¸ Hyunseok ) 한국정신간호학회 2021 정신간호학회지 Vol.30 No.3

        Purpose: The aim of this study was to determine the reliability and validity of the metacognition rating scale (MCRS), which is a revised version of the existing metacognition questionnaire (MCQ) with anger and anxiety added. Methods: A survey was conducted on 591 nursing students at colleges in North and South Gyeongsang Provinces, South Korea. The collected data were processed for the reliability and validity of the MCRS through Cronbach’s α and confirmatory factor analysis using SPSS 26.0. Results: Cronbach’s α for the reliability of MCRS was calculated at .88, .86, .77, .74, and .66 for five subfactors. Among the five subfactors, the first, second, third, and fifth factors showed high correlation in each of six items. Factor 4 was highly correlated in 5 out of 6 questions. Conclusion: The data confirm that the MCQ revised to include anger and anxiety is both reliable and valid for nursing students. Therefore, this scale can be used to identify the maladaptive metacognition of nursing students in stressful situations.

      • KCI등재

        지역원형으로서의 강원도와 이효석의 지리의식 연구 - 이효석 수필을 중심으로 -

        이미정 ( Lee Mijung ) 국제어문학회 ( 구 국제어문학연구회 ) 2018 국제어문 Vol.0 No.78

        본 논문은 지역원형으로서의 강원도 지역 담론과 이효석이 바라보는 지리적 인식의 연관성을 논의하고자 한다. 식민지 경험은 ‘조선적인 것’에 대한 발견을 가져왔으며, 제국의 시선에서 식민지 조선은 변방으로 그려졌다. 농촌과 도시는 이항 대립의 관계였고 특히 강원도는 도시문명과 단절된 미지의 공간으로 부각되는 대표적 공간이었다. 강원도 지역은 아름다움, 순박함, 경외함, 두려움, 민족 정체성 등 다양한 상징적 표상으로 묘사되었다. 이 모든 수식은 강원도를 타자화하는 다양한 관점들로 중앙과 변방이라는 이분법을 근간으로 복잡하게 형성되는 인문 지리적 공간이었다. 이효석의 바라보는 강원도의 지리 인식 역시 중앙과 변방이라는 이분법을 통해 해석된다. 그는 욕망의 대상으로서 서구적 아름다움을 지향했으며, 수필에 그려지는 자연은 인공적이고 조화를 중시하는 고전적 아름다움을 추구했다. 이효석의 고향은 자연의 아름다움으로 표현되는 공간으로 낭만적 세계관의 매개물에 불과했다. 이효석이 그리는 강원도 공간은 이국적이고 낯선 공간이라는 점에서 식민지 농촌 담론의 연장선상에 놓여 있다. 목가적인 풍경으로서 조화와 질서의 자연을 사랑했던 이효석에게 고향은 부정되어야 할 대상이거나 변모되어야 할 대상이었으며, 이와 같은 세계관을 통해 강원도에 대한 기억을 변주해 나갔다. This paper discusses the relationship between geographical cognition and Lee Hyosuk’s discourse in Gangwon province. The colonial experience gave the meaning of ‘Chosun’. The colonial Joseon dynasty was drawn on the edge. Rural areas and cities were related to each other. Especially, Gangwon - do was a typical space with urban civilization. The Gangwon-do region is described by various symbolic representations such as beauty, innocence, awe, fear, and national identity. All of these formulas are various aspects of Gangwon Province. The recognition of geography in Gangwon-do by Lee Hyoseok is also interpreted through the dichotomy between the center and the periphery. In his essay, he aimed for Western beauty as a subject of desire. He described the beauty of artificial, harmonious nature. Lee Hyoseok‘s hometown is a space expressed by the beauty of nature and a medium of romantic world view. The space of Gangwon-do that Lee Hyoseok draws is the same as the rural discourse of that era. Lee thought of his hometown as an object to be denied, and changed it to fit his own worldview.

      • KCI등재

        동심의 흐름과 변화 양상 연구: 이탁오ㆍ방정환ㆍ계급주의를 중심으로

        이미정 ( Lee Mijung ) 건국대학교 동화와번역연구소(구 건국대학교 중원인문연구소) 2018 동화와 번역 Vol.36 No.-

        이 글에서는 전통적 동심과 근대적 동심의 흐름과 변화 양상을 살폈다. 이탁오는 동심을 진심, 참된 마음이라고 보았다. 이탁오의 동심은 근대 동심과는 달리 철학적이며 비유적이었다. 이는 당시 근대적 의미의 아동이 인식되지 않은 까닭이었다. 방정환의 동심은 인간 마음의 원형에 주목했다는 점에서 이탁오의 동심과 유사하다. 그러나 참된 마음이 아니라 깨끗한 아름다움을 동심으로 이해하였다. 이는 실제 아동의 외양과 성품에서 비롯된 것이다. 더 나아가 이 깨끗한 아름다움을 ‘보호’해야 함을 강조하였다. 이는 근대에 ‘발견’된 아동에 대한 지식이 영향을 미쳤기 때문이다. 계급주의 아동문학가들 동심에도 계급이 있음을 강조하였다. 아동의 부모들은 모두 어떤 계급에든 속하여 있으므로 아동의 마음인 동심도 계급성을 띤다는 것이다. 부르주아의 횡포와 불합리한 현실을 인식하고 맞서고자 하는 프롤레타리아 아동의 동심은 정의감과 유사하다. 이탁오ㆍ방정환ㆍ계급주의 아동문학가들의 동심과 그 변화 양상을 통하여 인간 마음의 원형에서 그 시대가 갖고 있는 아동에 대한 지식이 결합되어 다양한 ‘동심’을 구성할 수 있음을 알 수 있었다. 그리고 ‘동심’ 연구가 지속되어야 하는 이유도 바로 여기에 있다. 동심은 아동이라는 기표를 설명할 수 있는 아직까지는 가장 유효한 기의이기 때문이다. In this article, I looked at the trend and changing pattern of traditional and modern childish innocence. Lee Tak-o saw childish innocence as a sincere, true mind. Childish innocence of Lee Tak-o was philosophical and figurative unlike that of modern times. This was because children were not recognized in the modern sense at the time. Bang Jeong-hwan's childish innocence is similar to Lee Tak-o's in that he focused on the prototype of the human mind. However, he understood not the true heart but the clean beauty as childish innocence. This came from the appearance and nature of real children. Furthermore, he emphasized the need to 'protect' this clean beauty. This is because the knowledge of modernly 'discovered' children has influenced him. He also emphasized the presence of class in childish innocence of writers of classist children's literature. His point is that children's parents are all belonging to any class, so childish innocence of children's mind also reveals class consciousness. Childish innocence of proletarian children who are aware of the absurd reality and seek to confront the bourgeois tyranny is similar to a sense of justice. Through childish innocence of proletarian children's literature including Lee Tak-o and Bang Jeong-hwan, and the changing pattern, it was found that the prototype of the human mind can be combined with the knowledge of the children of that age to form various 'childish innocence '. And here is why the study on 'childish innocence' should continue. Childish innocence is still the most valid signified to describe the signifier, children.

      • SCOPUSKCI등재

        A S trategic Human Resource Management Approach in Chaebol Hotels

        Mijung Kim(Mijung Kim),Yeonu Lee(Yeonu Lee) People&Global Business Association 2023 Global Business and Finance Review Vol.28 No.4

        Purpose: The purpose of this study is to examine how strategic human resource management practices are enacted in chaebol hotels, and also to evaluate the relationship between the SHRM practices and organizational effectiveness as experienced by employees, regarding the concept of organizational justice. Design/methodology/approach: The questionnaire survey for employees served to test hypotheses which examine the relationship between SHRM and the influence of these HR practices on organizational effectiveness, using multi-regression analysis. This research encompasses a total of 450 responses collected from individuals employed at chaebol hotels in Seoul and Busan. Findings: This study revealed that chaebol hotels hired competent employees who had language capabilities, used appearance as a selection criterion, and ensured that sophisticated selection methods were well established through the HR systems of numerous subsidiary companies. Employees consider the perceived injustices in the recruitment and selection process and the perceived unfairness in promotions. Research limitations/implications: All findings support the concept that the best practice, driven by collectivism, employment legislation, trade unions, and financial considerations, plays a significant role in managing HRM in chaebol hotels. This study contributes a new SHRM framework by integrating a combination of best fit, based on quality enhancement strategy, and best practices tailored to the specific organization. Originality/value: This study contributed to explore the SHRM framework for the Chaebol hotel sector with regard to providing both high quality of service and also a high price policy. This study provides guidelines for efficient SHRM to managers and practitioners who operate deluxe hotels and offers an essential material to gain a better understanding of a new SHRM framework in service organization.

      • KCI등재후보
      • Exosome-Based Delivery of miR-124 in a Huntington’s Disease Model

        Lee, Soon-Tae,Im, Wooseok,Ban, Jae-Jun,Lee, Mijung,Jung, Keun-Hwa,Lee, Sang Kun,Chu, Kon,Kim, Manho The Korean Movement Disorder Society 2017 Journal of movement disorders: official journal of Vol.10 No.1

        <P><B>Objective </B></P><P>Huntington’s disease (HD) is a genetic neurodegenerative disease that is caused by abnormal CAG expansion. Altered microRNA (miRNA) expression also causes abnormal gene regulation in this neurodegenerative disease. The delivery of abnormally downregulated miRNAs might restore normal gene regulation and have a therapeutic effect. </P><P><B>Methods </B></P><P>We developed an exosome-based delivery method to treat this neurodegenerative disease. miR-124, one of the key miRNAs that is repressed in HD, was stably overexpressed in a stable cell line. Exosomes were then harvested from these cells using an optimized protocol. The exosomes (Exo-124) exhibited a high level of miR-124 expression and were taken up by recipient cells. </P><P><B>Results </B></P><P>When Exo-124 was injected into the striatum of R6/2 transgenic HD mice, expression of the target gene, RE1-Silencing Transcription Factor, was reduced. However, Exo-124 treatment did not produce significant behavioral improvement. </P><P><B>Conclusion </B></P><P>This study serves as a proof of concept for exosome-based delivery of miRNA in neurodegenerative diseases.</P>

      • SCIESCOPUSKCI등재

        Effect of Berberine on Depression- and Anxiety-Like Behaviors and Activation of the Noradrenergic System Induced by Development of Morphine Dependence in Rats

        Lee, Bombi,Sur, Bongjun,Yeom, Mijung,Shim, Insop,Lee, Hyejung,Hahm, Dae-Hyun The Korean Society of Pharmacology 2012 The Korean Journal of Physiology & Pharmacology Vol.16 No.6

        The purpose of this study was to evaluate whether berberine (BER) administration could attenuate depression- and anxiety-like behaviors and increase corticotrophin-releasing factor (CRF) and tyrosine hydroxylase (TH) expression following chronic morphine withdrawal in rats. Male rats were exposed to chronic, intermittent, escalating morphine (10~50 mg/kg) for 10 days. After the last morphine injection, depression- and anxiety-like beahvior associated with morphine discontinuation persisted for at least three days during withdrawal without any change in ambulatory activity. Daily BER administration significantly decreased immobility in the forced swimming test and increased open-arm exploration in the elevated plus maze test. BER administration also significantly blocked the increase in hypothalamic CRF expression and TH expression in the locus coeruleus (LC) and the decrease in hippocampal brain-derived neurotrophic factor (BDNF) mRNA expression. Taken together, these findings demonstrated that BER administration significantly reduced morphine withdrawal-associated behaviors following discontinuation of repeated morphine administration in rats, possibly through modulation of hypothalamic CRF and the central noradrenergic system. BER may be a useful agent for treating or alleviating complex withdrawal symptoms and preventing morphine use relapses.

      • SCIESCOPUSKCI등재

        Chronic Administration of Baicalein Decreases Depression-Like Behavior Induced by Repeated Restraint Stress in Rats

        Lee, Bombi,Sur, Bongjun,Park, Jinhee,Kim, Sung-Hun,Kwon, Sunoh,Yeom, Mijung,Shim, Insop,Lee, Hyejung,Hahm, Dae-Hyun The Korean Society of Pharmacology 2013 The Korean Journal of Physiology & Pharmacology Vol.17 No.5

        Baicalein (BA), a plant-derived active flavonoid present in the root of Scutellaria baicalensis, has been widely used for the treatment of stress-related neuropsychiatric disorders including depression. Previous studies have demonstrated that repeated restraint stress disrupts the activity of the hypothalamic-pituitary-adrenal (HPA) axis, resulting in depression. The behavioral and neurochemical basis of the BA effect on depression remain unclear. The present study used the forced swimming test (FST) and changes in brain neurotransmitter levels to confirm the impact of BA on repeated restraint stress-induced behavioral and neurochemical changes in rats. Male rats received 10, 20, or 40 mg/kg BA (i.p.) 30 min prior to daily exposure to repeated restraint stress (2 h/day) for 14 days. Activation of the HPA axis in response to repeated restraint stress was confirmed by measuring serum corticosterone levels and the expression of corticotrophin-releasing factor in the hypothalamus. Daily BA administration significantly decreased the duration of immobility in the FST, increased sucrose consumption, and restored the stress-related decreases in dopamine concentrations in the hippocampus to near normal levels. BA significantly inhibited the stress-induced decrease in neuronal tyrosine hydroxylase immunoreactivity in the ventral tegmental area and the expression of brain-derived neurotrophic factor (BDNF) mRNA in the hippocampus. Taken together, these findings indicate that administration of BA prior to the repeated restraint stress significantly improves helpless behaviors and depressive symptoms, possibly by preventing the decrease in dopamine and BDNF expression. Thus, BA may be a useful agent for the treatment or alleviation of the complex symptoms associated with depression.

      • SCIESCOPUSKCI등재

        Wogonin Attenuates Hippocampal Neuronal Loss and Cognitive Dysfunction in Trimethyltin-Intoxicated Rats

        Lee, Bombi,Sur, Bongjun,Cho, Seong-Guk,Yeom, Mijung,Shim, Insop,Lee, Hyejung,Hahm, Dae-Hyun The Korean Society of Applied Pharmacology 2016 Biomolecules & Therapeutics(구 응용약물학회지) Vol.24 No.3

        We examined whether wogonin (WO) improved hippocampal neuronal activity, behavioral alterations and cognitive impairment, in rats induced by administration of trimethyltin (TMT), an organotin compound that is neurotoxic to these animals. The ability of WO to improve cognitive efficacy in the TMT-induced neurodegenerative rats was investigated using a passive avoidance test, and the Morris water maze test, and using immunohistochemistry to detect components of the acetylcholinergic system, brain-derived neurotrophic factor (BDNF), and cAMP-response element-binding protein (CREB) expression. Rats injected with TMT showed impairments in learning and memory and daily administration of WO improved memory function, and reduced aggressive behavior. Administration of WO significantly alleviated the TMT-induced loss of cholinergic immunoreactivity and restored the hippocampal expression levels of BDNF and CREB proteins and their encoding mRNAs to normal levels. These findings suggest that WO might be useful as a new therapy for treatment of various neurodegenerative diseases.

      • SCIESCOPUSKCI등재

        Effect of Beta-Asarone on Impairment of Spatial Working Memory and Apoptosis in the Hippocampus of Rats Exposed to Chronic Corticosterone Administration

        Lee, Bombi,Sur, Bongjun,Cho, Seong-Guk,Yeom, Mijung,Shim, Insop,Lee, Hyejung,Hahm, Dae-Hyun The Korean Society of Applied Pharmacology 2015 Biomolecules & Therapeutics(구 응용약물학회지) Vol.23 No.6

        ${\beta}$-asarone (BAS) is an active component of Acori graminei rhizoma, a traditional medicine used clinically in treating dementia and chronic stress in Korea. However, the cognitive effects of BAS and its mechanism of action have remained elusive. The purpose of this study was to examine whether BAS improved spatial cognitive impairment induced in rats following chronic corticosterone (CORT) administration. CORT administration (40 mg/kg, i.p., 21 days) resulted in cognitive impairment in the avoidance conditioning test (AAT) and the Morris water maze (MWM) test that was reversed by BAS (200 mg/kg, i.p). Additionally, as assessed by immunohistochemistry and RT-PCR analysis, the administration of BAS significantly alleviated memory-associated decreases in the expression levels of brain-derived neurotrophic factor (BDNF) and cAMP-response element-binding protein (CREB) proteins and mRNAs in the hippocampus. Also, BAS administration significantly restored the expression of Bax and Bcl-2 mRNAs in the hippocampus. Thus, BAS may be an effective therapeutic for learning and memory disturbances, and its neuroprotective effect was mediated, in part, by normalizing the CORT response, resulting in regulation of BDNF and CREB functions and anti-apoptosis in rats.

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