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자기공명혈관조영술을 이용한 관상동맥 크기 nitinol 스텐트의 평가
현민수,Masahiro Terashima,Michael V. McConnell 순천향의학연구소 2006 Journal of Soonchunhyang Medical Science Vol.12 No.2
Background. Artifacts from stainless steel stents prohibit the assessment of stent patency with magnetic resonance angiography (MRA). Nitinol stents have less artifacts. The use of high radiofrequency flip angle (FA) sequence may improve the signal within the stents. We evaluated coronary-size nitinol stent patency with high FA MRA in the rabbit aortic model. Methods. Coronary-size nitinol stents (3.0-4.0 mm x 14-30 mm, Radius™, Boston Scientific, Natick, MA) were deployed in the aorta of six New Zealand White rabbits and imaged with MRA at day 2. A 1.5 Tesla GE MRI system (Signa, GE Medical Systems, Milwaukee, WI) with a standard extremity coil and high-performance gradients (40 mT/m, 150 T/m/s) was used. A multi-slice interleaved spiral coronary MRA sequence was used with a specially designed RF pulse to allow FA up to 140˚. Parameters were typical for patient coronary MRA studies (20 cm FOV, 0.6 x 0.6 x 3 mm, 20 interleaves, TR = 1000 ms, TE=7ms, = 60˚ , 90˚ , 120˚ , and 140˚). In-stent lumen signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) compared to adjacent muscle were analyzed. Results. The spiral coronary MRA sequence clearly imaged within the nitinol stents in all cases. Both SNR and CNR of the lumen signal significantly improved with increasing FA. SNR increased significantly from 60˚ to 140˚ (23.1+6.1 to 41.6+9.0, p < 0.01). And CNR also increased significantly(1.9±3.3 to 25.2±9.4, p = 0.01). Condusion. We could image and evaluate the coronary-size nitinol stent patency with high FA MRA in the rabbit aortic model.