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- 저자 : Masthan, K.M.K. (검색결과 3 건)
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Advanced Diagnostic Aids in Oral Cancer
Masthan, K.M.K.,Babu, N. Aravindha,Dash, Kailash Chandra,Elumalai, M. Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.8
Oral cancers are one of the most common cancers worldwide today. They are usually neglected by the common population when compared to systemic cancers such as the lung cancer, colon cancer etc. However, they also may be extremely fatal if left untreated even at a very initial stage of the lesion. Early detection and treatment gives the best chance for its cure. The five-year survival rate of oral cancer still remains low and delayed diagnosis is suggested to be one of the major reasons. The detection and diagnosis are currently based on clinical examination, histopathological evaluation of the biopsy material and molecular methods. Several diagnostic aids have been developed over the years for early detection of oral cancer. The purpose of this article is to review the advanced available diagnostic adjuncts for the detection of oral cancer.
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S A R Sheik Masthan,Kanagaraj G,Yu Vincent F 한국CDE학회 2023 Journal of computational design and engineering Vol.10 No.5
Inverse kinematics is one of the most complicated problems in robotics. The inverse kinematics calculation is the basis for any industrial robot’s ability to plan and follow a trajectory. This paper proposes a hybrid algorithm, e3GSA, based on the gravitational search algorithm (GSA) for solving the inverse kinematics problem of an n-link redundant robot manipulator. The algorithm’s efficiency was evaluated using a fitness function comprising of position error, orientation error, and collision error, and it was found to perform better than the conventional GSA in simulations. A generalized framework was proposed and tested by simulating a 6-, 8-, and 12-link robot manipulators. Experimental validation is carried out using a 6-link robot manipulator, which shows that the simulation data are on par with the experimental data. The proposed algorithm was also found to perform adaptively with faster convergence rates and lesser computation time, making it a better choice for other engineering problems that can be transformed into optimization problems.
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Apoptosis in Cancer - An Update
Sankari, S. Leena,Masthan, K.M.K.,Babu, N. Aravindha,Bhattacharjee, Tathagata,Elumalai, M. Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.10
Apoptosis is programmed cell death which is essential for development and survival of living organisms. It is a sequentially regulated suicidal programme where cells activate certain enzymes which dissolute their own nuclear component and various protein component of nucleus and cytoplasm. Disturbance of this regulatory pathway may lead to various diseases like autoimmune diseases, neurodegenerative diseases and cancers. The potential mechanisms of apoptosis and its role in cancer are discussed. The ability of apoptosis to modulate the life or death of a cell is also recognized for its immense therapeutic potential. Understanding the mechanisms from this review will give us better insight to the pathogenesis of various diseases including cancer and will open new horizons to therapeutic approaches.
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