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- 저자 : Mantha, Srinivas (검색결과 4 건)
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Mantha, Kameswara Bharadwaj,McIntosh, Daniel H,Brennan, Ryan,Ferguson, Henry C,Kodra, Dritan,Newman, Jeffrey A,Rafelski, Marc,Somerville, Rachel S,Conselice, Christopher J,Cook, Joshua S,Hathi, Nimish Oxford University Press 2018 MONTHLY NOTICES- ROYAL ASTRONOMICAL SOCIETY Vol.475 No.2
<P>The rate of major galaxy-galaxy merging is theoretically predicted to steadily increase with redshift during the peak epoch of massive galaxy development (1 <= z <= 3). We use close-pair statistics to objectively study the incidence of massive galaxies (stellar M1 > 2 x 10(10)M(circle dot)) hosting major companions (1 <= M-1/M-2 <= 4; i.e. <4: 1) at six epochs spanning 0 < z < 3. We select companions from a nearly complete, mass-limited (>= 5 x 10(9)M(circle dot)) sample of 23 696 galaxies in the five Cosmic Assembly Near-Infrared Deep Extragalactic Legacy Survey fields and the Sloan Digital Sky Survey. Using 5-50 kpc projected separation and close redshift proximity criteria, we find that the major companion fraction f(mc)(z) based on stellar mass-ratio (MR) selection increases from 6 per cent (z similar to 0) to 16 per cent (z similar to 0.8), then turns over at z similar to 1 and decreases to 7 per cent (z similar to 3). Instead, if we use a major F160W flux-ratio (FR) selection, we find that f(mc)(z) increases steadily until z similar to 3 owing to increasing contamination from minor (MR > 4: 1) companions at z > 1. We show that these evolutionary trends are statistically robust to changes in companion proximity. We find disagreements between published results are resolved when selection criteria are closely matched. If we compute merger rates using constant fraction-to-rate conversion factors (C-merg,C-pair = 0.6 and T-obs,T-pair = 0.65 Gyr), we find that MR rates disagree with theoretical predictions at z > 1.5. Instead, if we use an evolving T-obs,T-pair(z) alpha (1 + z)- 2 from Snyder et al., our MR-based rates agree with theory at 0 < z < 3. Our analysis underscores the need for detailed calibration of C-merg,C-pair and T-obs,T-pair as a function of redshift, mass, and companion selection criteria to better constrain the empirical major merger history.</P>
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Dhanasekaran, V.,Soundaram, N.,Kim, Seong-Il,Chandramohan, R.,Mantha, Srinivas,Saravanakumar, S.,Mahalingam, T. The Royal Society of Chemistry 2014 NEW JOURNAL OF CHEMISTRY Vol.38 No.6
<P>We have reported on the synthesis of CuO nanostructures <I>via</I> a simple sol–gel approach with high yield at low cost by the reduction of aqueous solutions of Cu(NO<SUB>3</SUB>)<SUB>2</SUB> and Na<SUB>2</SUB>NO<SUB>3</SUB>. Synthesized nanostructures were characterized using X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDX), fluorescence spectroscopy, Raman scattering and UV-Vis-NIR spectroscopy. Structural studies revealed that the prepared CuO nanostructures were polycrystalline in nature with monoclinic structure. The crystallite size of CuO nanostructures was estimated to be ∼10 nm using Debye–Scherrer's formula. The uniform and nanoregime grains were observed in SEM micrographs. The optical band gap value was estimated to be 1.2 eV using Tauc's plot. The Raman scattering investigations revealed A<SUB>g</SUB> and B<SUB>g</SUB> mode peaks at 278 cm<SUP>−1</SUP>, 332 cm<SUP>−1</SUP> and 618 cm<SUP>−1</SUP>, respectively.</P> <P>Graphic Abstract</P><P>A<SUB>g</SUB> and B<SUB>g</SUB> mode vibration peaks are observed in the Raman spectrum with a lower optical band gap of 1.2 eV. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c4nj00084f'> </P>
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Shweta Thakur,Bibekananda Sarkar,Ravi P Cholia,Nandini Gautam,Monisha Dhiman,Anil K Mantha 생화학분자생물학회 2014 Experimental and molecular medicine Vol.46 No.-
Apurinic/apyrimidinic endonuclease 1 (APE1) is a multifunctional enzyme involved in the base excision repair (BER) pathway, which repairs oxidative base damage caused by endogenous and exogenous agents. APE1 acts as a reductive activator of many transcription factors (TFs) and has also been named redox effector factor 1, Ref-1. For example, APE1 activates activator protein-1, nuclear factor kappa B, hypoxia-inducible factor 1a, paired box gene 8, signal transducer activator of transcription 3and p53, which are involved in apoptosis, inflammation, angiogenesis and survival pathways. APE1/Ref-1 maintains cellular homeostasis (redox) via the activation of TFs that regulate various physiological processes and that crosstalk with redox balancing agents (for example, thioredoxin, catalase and superoxide dismutase) by controlling levels of reactive oxygen and nitrogen species. The efficiency of APE1/Ref-1’s function(s) depends on pairwise interaction with participant protein(s), the functions regulated by APE1/Ref-1 include the BER pathway, TFs, energy metabolism, cytoskeletal elements and stressdependent responses. Thus, APE1/Ref-1 acts as a ‘hub-protein’ that controls pathways that are important for cell survival. In this review, we will discuss APE1/Ref-1’s versatile nature in various human etiologies, including neurodegeneration, cancer, cardiovascular and other diseases that have been linked with alterations in the expression, subcellular localization and activities of APE/Ref-1. APE1/Ref-1 can be targeted for therapeutic intervention using natural plant products that modulate the expression and functions of APE1/Ref-1. In addition, studies focusing on translational applications based on APE1/Ref-1-mediated therapeutic interventions are discussed.
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Complications Following Transradial Cerebral Angiography : An Ultrasound Follow-Up Study
Yoon, Wonki,Kwon, Woo-Keun,Choudhri, Omar,Ahn, Jaegeun,Huh, Hanyong,Ji, Choel,Do, Huy M.,Mantha, Aditya,Jeun, Sin-Soo The Korean Neurosurgical Society 2018 Journal of Korean neurosurgical society Vol.61 No.1
Objective : The feasibility and usefulness of transradial catheterization for coronary and neuro-intervention are well known. However, the anatomical change in the catheterized radial artery (RA) is not well understood. Herein, we present the results of ultrasonographic observation of the RA after routine transradial cerebral angiography (TRCA). Methods : Patients who underwent routine TRCA with pre- and post-procedure Doppler ultrasonography (DUS) of the catheterized RA were enrolled. We then recorded and retrospectively reviewed the diameter and any complicated features of the RA observed on DUS, and the factors associated with the diameter and complications were analyzed. Results : A total of 223 TRCAs across 181 patients were enrolled in the current study. The mean RA diameter was 2.48 mm and was positively correlated with male gender (p<0.001) and hypertension (p<0.002). The median change in diameter after TRCA was less than 0.1 mm (range, -1.3 to 1.2 mm) and 90% of changes were between -0.8 and +0.7 mm. Across 228 procedures, there were 12 cases (5.3%) of intimal hyperplasia and 22 cases (9.6%) of asymptomatic local vascular complications found on DUS. Patients with abnormal findings on the first procedure had a smaller pre-procedural RA diameter than that of patients without findings (2.26 vs. 2.53 mm, p=0.0028). There was no significant difference in the incidence of abnormal findings for the first versus subsequent procedures (p=0.68). Conclusion : DUS identified the pre- and post-procedural diameter and local complications of RA. Routine TRCA seems to be acceptable with regard to identifying local complications and changes in RA diameter.
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