(주)비비테크의 반도체장비 사업 성공과 글로벌화 노력

임채숙(Lim, Chae-suk),이민상(Lee, Min-Sang) 한국문화산업학회 2013 문화산업연구 Vol.13 No.4

한국은 현재 세계 1위의 반도체 생산대국으로 성장하였고, 반도체메모리 분야에서는 공급능력이나 공정기술, 가격 및 품질 면에서 세계 최고의 경쟁력을 보유하고 있다. 반면에, 반도체장비 산업은 원천 기술의 부족으로 인해 상당한 부분을 수입에 의존하고 있는 실정이며, 기술적인 장벽이 상대적으로 낮은 후(後)공정 장치에 편중되어 기술 확보 및 부품 산업 육성과 수익률 측면에서 어려움이 많다. ㈜비비테크(B.B.TECH. Co.)는 최첨단 반도체장비의 clean roomengineering 및 high quality utility construction을 추구하는 회사로서, ‘최고의 기술력을 확보하여 최상의 서비스를 제공한다’는 경영이념 아래 세계 최고의 기술력과 품질 및 생산성을 갖고 있다. 본 연구는 반도체장비 시장에서 우수한 성과를 나타내고 있는 (주)비비테크의 성공사례를 바탕으로, 고속으로 성장할 수 있었던 요인, 당면하였던 위기 극복 과정, 그리고 해외진출 전략에 대하여 분석함으로써 강소기업의 해외 진출 전략에 관한 전략적 시사점을 살펴보고, 이를 토대로 최첨단 반도체장비 산업분야에서의 발전방향을 제시하고자 한다. 사례분석을 통해 나타난 ㈜비비테크의 성공비결은 다음과 같다. 2004년 4월에 설립하여 초고속으로 성장한 ㈜비비테크는 성열학 사장 중심의 독보적인 기술력과 열정을 가지고 있었다. 당시 세계 반도체 시장의 침체와 한국 시장의 한계에 직면한 ㈜비비테크은 새로운 성장 동력을 찾기 위해 끊임없이 노력하며, 최첨단·저비용·고품질이라는 차별성으로 clean room 대중화를 시도하였다. ㈜비비테크는 독자적인 ‘기술력’과 ‘도전의식’으로 미국과 중국 시장으로 진출하였으며, ‘스마일 경영’이라는 독특한 혁신적인 조직문화를 이루어 노사간의 긴밀한 협력관계를 이루어냈다. 본 연구는 다변화하는 경영환경에서 기업의 성공요인을 살펴봄으로써 이와 비슷한 환경에 처해있는 기업에게 유용한 전략적 시사점을 제공한다. B.B. Tech. Co. (hereafter B.B. Tech) has been one of the top-notch high tech manufacturers in Korea, producing equipments of semiconductors, Clean Room Engineering, and Quality Utility Construction. This study analyzes factors contributable to the rapid growth of B.B. Tech, explains as to how it has strived to overcome challenges it had faced with, and draws strategic implications of its successful global expansion ventures. The admiring achievements of B.B. Tech are summarized as follows. The growth of B.B. Tech, founded in 2004, has been driven by the vision and passion for new technology development, possessed by the founder and CEO, Yeol-Hak Sung. Seeking a strategic alternative, however, B.B. Tech started turing to global market expansions. It also has expanded its product portfolios and customer markets by diversifying into the CLEAN ROOM popularization in differentiation of cutting edge, low-cost, high-quality. Targeting USA and China, B.B. Tech has rapidly grown its manufacturing capacity and productivity through its technological edge and the Innovative Corporate Culture of challenge. This study provides managerial implications to companies that are to deal with turbulent environmental changes and sustainable growth simultaneously. 한국은 현재 세계 1위의 반도체 생산대국으로 성장하였고, 반도체메모리 분야에서는 공급능력이나 공정기술, 가격 및 품질 면에서 세계 최고의 경쟁력을 보유하고 있다. 반면에, 반도체장비 산업은 원천 기술의 부족으로 인해 상당한 부분을 수입에 의존하고 있는 실정이며, 기술적인 장벽이 상대적으로 낮은 후(後)공정 장치에 편중되어 기술 확보 및 부품 산업 육성과 수익률 측면에서 어려움이 많다. ㈜비비테크(B.B.TECH. Co.)는 최첨단 반도체장비의 clean roomengineering 및 high quality utility construction을 추구하는 회사로서, ‘최고의 기술력을 확보하여 최상의 서비스를 제공한다’는 경영이념 아래 세계 최고의 기술력과 품질 및 생산성을 갖고 있다. 본 연구는 반도체장비 시장에서 우수한 성과를 나타내고 있는 (주)비비테크의 성공사례를 바탕으로, 고속으로 성장할 수 있었던 요인, 당면하였던 위기 극복 과정, 그리고 해외진출 전략에 대하여 분석함으로써 강소기업의 해외 진출 전략에 관한 전략적 시사점을 살펴보고, 이를 토대로 최첨단 반도체장비 산업분야에서의 발전방향을 제시하고자 한다. 사례분석을 통해 나타난 ㈜비비테크의 성공비결은 다음과 같다. 2004년 4월에 설립하여 초고속으로 성장한 ㈜비비테크는 성열학 사장 중심의 독보적인 기술력과 열정을 가지고 있었다. 당시 세계 반도체 시장의 침체와 한국 시장의 한계에 직면한 ㈜비비테크은 새로운 성장 동력을 찾기 위해 끊임없이 노력하며, 최첨단·저비용·고품질이라는 차별성으로 clean room 대중화를 시도하였다. ㈜비비테크는 독자적인 ‘기술력’과 ‘도전의식’으로 미국과 중국 시장으로 진출하였으며, ‘스마일 경영’이라는 독특한 혁신적인 조직문화를 이루어 노사간의 긴밀한 협력관계를 이루어냈다. 본 연구는 다변화하는 경영환경에서 기업의 성공요인을 살펴봄으로써 이와 비슷한 환경에 처해있는 기업에게 유용한 전략적 시사점을 제공한다. B.B. Tech. Co. (hereafter B.B. Tech) has been one of the top-notch high tech manufacturers in Korea, producing equipments of semiconductors, Clean Room Engineering, and Quality Utility Construction. This study analyzes factors contributable to the rapid growth of B.B. Tech, explains as to how it has strived to overcome challenges it had faced with, and draws strategic implications of its successful global expansion ventures. The admiring achievements of B.B. Tech are summarized as follows. The growth of B.B. Tech, founded in 2004, has been driven by the vision and passion for new technology development, possessed by the founder and CEO, Yeol-Hak Sung. Seeking a strategic alternative, however, B.B. Tech started turing to global market expansions. It also has expanded its product portfolios and customer markets by diversifying into the CLEAN ROOM popularization in differentiation of cutting edge, low-cost, high-quality. Targeting USA and China, B.B. Tech has rapidly grown its manufacturing capacity and productivity through its technological edge and the Innovative Corporate Culture of challenge. This study provides managerial implications to companies that are to deal with turbulent environmental changes and sustainable growth simultaneously.

Electric power consumption predictive modeling of an electric propulsion ship considering the marine environment

Lim, Chae-og,Park, Byeong-cheol,Lee, Jae-chul,Kim, Eun Soo,Shin, Sung-chul The Society of Naval Architects of Korea 2019 International Journal of Naval Architecture and Oc Vol.11 No.2

This study predicts the power consumption of an Electric Propulsion Ship (EPS) in marine environment. The EPS is driven by a propeller rotated by a propulsion motor, and the power consumption of the propeller changes by the marine environment. The propulsion motor consumes the highest percentage of the ships' total power. Therefore, it is necessary to predict the power consumption and determine the power generation capacity and the propeller capacity to design an efficient EPS. This study constructs a power estimation simulator for EPS by using a ship motion model including marine environment and an electric power consumption model. The usage factor that represents the relationship between power consumption and propulsion is applied to the simulator for power prediction. Four marine environment scenarios are set up and the power consumed by the propeller to maintain a constant ship speed according to the marine environment is predicted in each scenario.

Overexpression of the pepper antimicrobial protein CaAMP1 gene regulates the oxidative stress- and disease-related proteome in Arabidopsis

Chae Woo Lim,Sung Chul Lee 한국육종학회 2011 한국육종학회 학술발표회 발표요지 Vol.43 No.-

Phenotypic and genetic characterization of adult T-cell acute lymphoblastic leukemia with del(9)(q34);SET-NUP214 rearrangement.

Chae, Hyojin,Lim, Jihyang,Kim, Myungshin,Park, Joonhong,Kim, Yonggoo,Han, Kyungja,Lee, Seok,Min, Woo Sung Springer International 2012 Annals of hematology Vol.91 No.2

<P>SET-NUP214 rearrangement is a recently recognized recurrent chromosomal translocation mostly observed in T-ALL. In order to characterize this rare entity, we performed phenotypic and genetic characterization of SET-NUP214 rearrangement through an investigation of a series of 40 consecutive samples of adult T-ALL that was selected among 229 adult ALL cases during 4?years in a single institution. Four cases (10%) of SET-NUP214 translocation were identified in our study. In all cases, diagnosis of T-ALL was established according to the World Health Organization (WHO) classification, and clonal TCR rearrangements were found. The immunophenotypic markers were indicative of the precursor nature of T lymphoblasts, and they expressed one or both of the myeloid-associated antigens (CD13, CD33). Conventional cytogenetic analysis revealed complex chromosomal aberrations in all four SET-NUP214 rearranged cases and del(12)(p13)/ETV6 was frequently involved. Array-CGH demonstrated additional genomic imbalances in addition to deletion 9q34. The genomic breakpoint sequencing identified breakpoints at SET intron 7 and NUP214 intron 17, and random nucleotide addition was found in two cases at the site of rearrangement. Our independently derived data set from a single institution confirms previous findings of SET-NUP214 rearrangement, indicates the relatively high incidence of SET-NUP214 rearrangement in adult T-ALLs, and also demonstrates comprehensive clinical, phenotypic, and genetic characteristics of this entity. Also, our report on genomic breakpoints demonstrates the homogeneity in the localization of the genomic breakpoints at 9q34. Concurrent chromosomal aberrations identified in this study should provide further areas of interest in investigation of SET-NUP214-mediated leukemogenesis.</P>

Performing Contralateral Central Lymph Node Dissection in Papillary Thyroid Carcinoma: A Decision Approach

Chae, Byung Joo,Jung, Chan Kwon,Lim, Dong Jun,Song, Byung Joo,Kim, Jeong Soo,Jung, Sang Seol,Bae, Ja Seong Mary Ann Liebert 2011 Thyroid Vol.21 No.8

<P>Substantial controversy exists over the role of prophylactic neck dissection for patients with papillary thyroid carcinoma (PTC). We hypothesized that a therapeutic strategy of performing a routine intraoperative frozen section of the ipsilateral central lymph node (CLN) after elective ipsilateral CLN dissection (CLND) for all unilateral PTC and then performing a contralateral CLND if the frozen section is positive for malignancy would reduce morbidity compared to a therapeutic strategy of routine bilateral CLND.</P>

Electrochemical Zinc-Ion Intercalation Properties and Crystal Structures of ZnMo₆S₈ and Zn₂Mo₆S₈ Chevrel Phases in Aqueous Electrolytes

Chae, Munseok S.,Heo, Jongwook W.,Lim, Sung-Chul,Hong, Seung-Tae American Chemical Society 2016 Inorganic Chemistry Vol.55 No.7

<P>The crystal structures and electrochemical properties of ZnxMo6S8 Chevrel phases (x = 1, 2) prepared via electrochemical Zn2+-ion intercalation into the Mo6S8 host material, in an aqueous electrolyte, were characterized. Mo6S8 [trigonal, R (3) over bar, a = 9.1910(6) angstrom, c = 10.8785(10) angstrom, Z = 3] was first prepared via the chemical extraction of Cu ions from Cu2Mo6S8, which was synthesized via a solid-state reaction for 24 h at 1000 degrees C. The electrochemical zinc-ion insertion into Mo6S8 occurred stepwise, and two separate potential regions were depicted in the cyclic voltammogram (CV) and galvanostatic profile. ZnMo6S8 first formed from Mo6S8 in the higher-voltage region around 0.45-0.50 V in the CV, through a pseudo two-phase reaction. The inserted zinc ions occupied the interstitial sites in cavities surrounded by sulfur atoms (Zn1 sites). A significant number of the inserted zinc ions were trapped in these Znl sites, giving rise to the first-cycle irreversible capacity of similar to 46 mAh g(-1) out of the discharge capacity of 134 mAh g(-1) at a rate of 0.05 degrees C. In the lower-voltage region, further insertion occurred to form Zn2Mo6S8 at around 0.35 V in the CV, also involving a two-phase reaction. The electrochemical insertion and extraction into the Zn2 sites appeared to be relatively reversible and fast. The crystal structures of Mo6S8, ZnMo6S8, and Zn2Mo6S8 were refined using X-ray Rietveld refinement techniques, while the new structure of Zn2Mo6S8 was determined for the first time in this study using the technique of structure determination from powder X-ray diffraction data. With the zinc ions inserted into Mo6S8 forming Zn2Mo6S8, the cell volume and a parameter increased by 5.3% and 5.9%, respectively, but the c parameter decreased by 6.0%. The average Mo-Mo distance in the Mo-6 cluster decreased from 2.81 to 2.62 angstrom.</P>

Nitrate inhibits soybean nodulation by regulating expression of CLE genes

Lim, Chae Woo,Lee, Young Woo,Lee, Sung Chul,Hwang, Cheol Ho Elsevier 2014 Plant science Vol.229 No.-

<P><B>Abstract</B></P> <P>Nitrogen compounds such as nitrate act as a potential inhibitor for legume nodulation. In this study, we isolated a new CLE gene, <I>GmNIC2</I>, from nitrate-treated roots, which shares high sequence homology with nitrate-induced CLE gene <I>GmNIC1</I>. Similar to <I>GmNIC1</I>, the expression level of <I>GmNIC2</I> was not significantly altered in roots by rhizobial inoculation and was much higher in young nodules than in roots. In addition, overexpression of <I>GmNIC2</I> led to similar nodulation inhibition of transgenic hairy roots to that of <I>GmNIC1</I>, which occurred in GmNARK-dependent manner and at the local level. By analyzing GmNARK loss-of-function mutant, SS2-2, it was found that expression levels of <I>GmNIC1</I> and <I>GmNIC2</I> in the SS2-2 roots were lower than in the wild type (WT) roots in response to nitrate. In contrast to <I>GmNIC1</I> and <I>GmNIC2</I>, expressions of <I>GmRIC1</I> and <I>GmRIC2</I> genes that are related to the autoregulation of nodulation (AON) were strongly suppressed both of the soybeans during all periods of nitrate treatment and even were not induced by additional inoculation with rhizobia. Taken together, the results of this study suggest that GmNIC2, as an active homologous gene located in chromosome 13, acts locally to suppress nodulation, like GmNIC1, and nitrate inhibition of nodulation is led by fine-tuned regulation of both nitrate-induced CLEs and rhizobia-induced CLEs.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A new nitrate-induced CLE gene, <I>GmNIC2</I>, is isolated from soybean roots. </LI> <LI> GmNIC2 acts as a local signal in nitrate inhibition of nodulation, like GmNIC1. </LI> <LI> Nitrate induces lower expression of <I>GmNIC</I> genes in the supernodulation mutant. </LI> <LI> Nitrate inhibits expression of rhizobia-induced <I>CLEs</I> after rhizobial inoculation. </LI> <LI> Nitrate inhibition of nodulation is led by a fine-tune regulation between CLEs. </LI> </UL> </P>

Risk prediction for 30-day heart failure-specific readmission or death after discharge: Data from the Korean Acute Heart Failure (KorAHF) registry

Lim, Nam-Kyoo,Lee, Sang Eun,Lee, Hae-Young,Cho, Hyun-Jai,Choe, Won-Seok,Kim, Hokon,Choi, Jin Oh,Jeon, Eun-Seok,Kim, Min-Seok,Kim, Jae-Joong,Hwang, Kyung-Kuk,Chae, Shung Chull,Baek, Sang Hong,Kang, Seo Elsevier 2019 Journal of cardiology Vol.73 No.2

<P><B>Abstract</B></P> <P><B>Background</B></P> <P>Identifying patients with acute heart failure (HF) at high risk for readmission or death after hospital discharge will enable the optimization of treatment and management. The objective of this study was to develop a risk score for 30-day HF-specific readmission or death in Korea.</P> <P><B>Methods</B></P> <P>We analyzed the data from the Korean Acute Heart Failure (KorAHF) registry to develop a risk score. The model was derived from a multiple logistic regression analysis using a stepwise variable selection method. We also proposed a point-based risk score to predict the risk of 30-day HF-specific readmission or death by simply summing the scores assigned to each risk variable. Model performance was assessed using an area under the receiver operating characteristic curve (AUC), the Hosmer–Lemeshow goodness-of-fit test, the net reclassification improvement (NRI), and the integrated discrimination improvement (IDI) index to evaluate discrimination, calibration, and reclassification, respectively.</P> <P><B>Results</B></P> <P>Data from 4566 patients aged ≥40 years were included in the analysis. Among them, 446 (9.8%) had 30-day HF-specific readmission or death. The final model included 12 independent variables (age, New York Heart Association functional class, clinical history of hypertension, HF admission, chronic obstructive pulmonary disease, etiology of cardiomyopathy, systolic blood pressure, left ventricular ejection fraction, serum sodium, brain natriuretic peptide, N-terminal prohormone of brain natriuretic peptide at discharge, and prescription of β-blockers and angiotensin-converting enzyme inhibitors or angiotensin II receptor antagonists at discharge). The point risk score showed moderate discrimination (AUC of 0.710; 95% confidence interval, 0.685–0.735) and good calibration (<I>χ</I> <SUP>2</SUP> =8.540, <I>p</I> =0.3826).</P> <P><B>Conclusions</B></P> <P>The risk score for the prediction of the risk of 30-day HF-specific readmission or death after hospital discharge was developed using 12 predictors. It can be utilized to guide appropriate interventions or care strategies for patients with HF.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The risk of 30-day heart failure (HF) readmission or death can be estimated with 12 variables. </LI> <LI> The risk for short-term HF-specific readmission or death can be calculated easily. </LI> <LI> The model has the potential to reduce readmission by identifying high-risk patients. </LI> <LI> The risk model can be utilized to guide suitable interventions or care in patients. </LI> </UL> </P>

A novel microbial platform for the Biorefinery of Brown Macroalgae; Vibrio sp. dhg

Sung Hwa WOO,Hyun Gyu LIM,Dong hun KWAK,Sungwoo PARK,Jae-Seong YANG,Chae Won KANG,Beomhee KIM,Myung Hyun NOH,Sang Woo SEO,Gyoo Yeol JUNG 한국생물공학회 2019 한국생물공학회 학술대회 Vol.2019 No.4

High-dose versus Low-dose 5-Fluorouracil and Cisplatin Based Hepatic Arterial Infusion Chemotherapy for Advanced Hepatocellular Carcinoma

( Chae-june Lim ),( Ji-yun Hong ),( Yang-seok Ko ),( Min-woo Chung ),( Chung-hwan Jun ),( Sung-kyu Choi ),( Sung-bum Cho ) 대한간암학회 2019 대한간암학회지 Vol.19 No.1

Backgrounds/Aims: Hepatic arterial infusion chemotherapy (HAIC) has been reported as an effective treatment for advanced hepatocellular carcinoma. The aim of this study is to compare the effect and safety between a high-dose regimen (750 mg/m2 5-fluorouracil [FU] and 25 mg/m2 cisplatin on day 1-4) and a low-dose regimen (500 mg/m2 5-FU on day 1-3 with 60 mg/m2 cisplatin on day 2). Methods: A total of 48 patients undergoing HAIC were retrospectively analyzed. Thirty-two patients were treated with the high-dose and 16 patients with the low-dose regimen. Results: Complete response (CR), partial response (PR), stable disease (SD), and progressive disease were noted in one (3.1%), 15 (46.9%), three (9.4%), and 13 patients (40.6%) in the highdose group, and 0 (0%), one (6.3%), eight (50%), and seven patients (43.8%) in the low-dose group (p=0.002). The disease control rate (CR, PR, and SD) did not differ between groups (59.4% vs. 56.3%, p=1.000), but the objective response rate (CR and PR) was significantly higher in the high-dose group (50.0% vs. 6.3%, p=0.003). The median progression free survival did not differ between groups (4.0 vs. 6.0, p=0.734), but overall survival was significantly longer in the high-dose group (not reached vs. 16.0, p=0.028). Fourteen (43.8%) patients in the highdose group and two patients (12.5%) in the low-dose group experienced grade 3-4 toxicities (p=0.050). Conclusions: High dose HAIC may achieve better tumor response and may improve overall survival compared to a low-dose regimen. However, the high-dose regimen should be administered cautiously because of the higher incidence of adverse events. (J Liver Cancer 2019;19:38-45)