八味地黃丸과 六味地黃丸의 效能에 關한 文獻的 考察

李彦政,宋峰根,金永學,오로사 대한동의병리학회 1996 동의생리병리학회지 Vol.10 No.2

八味地黃丸과 六味地黃丸은 漢代 張仲景의 〈金궤要略〉과 宋代 錢乙의 〈小兒樂證直訣〉에 각각 처음 收錄된 이래 歷代 醫學에 八味地黃丸은 腎陰虛에 사용되어 왔으며 六味地黃丸은 腎陽虛에 사용되는 處方으로 기록되어 왔다. 이에 저자는 腎陽虛 및 腎陰虛에 광범위하게 應用되는 八味地黃丸과 六味地黃丸의 效能, 主治, 現代 臨床活用, 藥理作用에 대해 考察하였다. 그 결과 八味地黃丸 效能은 溫和腎氣, 溫補腎陽하며, 六味地黃丸 效能은 滋腎陰 補肝血 制火로 要約할 수 있었으며, 八味地黃丸은 腎氣不足, 腎陽不足으로 인한 面色蒼白, 頭昏, 耳鳴, 腰酸脚軟, 身半以下常有冷感, 小便不利 或 頻數 脈沈遲 或虛弱, 消渴, 水腫, 久泄, 轉胞, 男子陽위 또는 女子子宮虛寒으로 인한 不姙, 舌淡笞白 等의 諸般 證狀을 治療하는데 사용되어 왔으며, 八味地黃丸은 腎陰不足이나 肝腎不足으로 인한 陰虛發熱을 포함한 骨蒸潮熱 或 手心煩熱, 頭目眩??, 耳??, 咽喉燥痛, 齒牙不固, 腰腿수軟, 遺精, 消渴, 舌紅少苔 或 無苔 脈細, 少便淋閉, 五臟虧損, 自汗溫汗, 諸血 等의 諸般 證狀을 治療하는데 활용되었음을 알 수 있었다. 최근에는 泌尿器系疾患, 高血壓, 糖尿病, 精神疾患, 老人性 眼疾患, 慢性 呼吸器疾患 等에 八味地黃丸과 六味地黃丸이 공통적으로 活用되고 있으며, 性機能 및 生殖器疾患 등에는 八味地黃丸이 活用되며, 甲狀腺機能亢進症, 消花器系, 癌類, 小兒 營養不良 等에는 六味地黃丸이 活用되고 있는 것으로 나타났다. 아울러 八味地黃丸과 六味地黃丸의 藥理作用은 모두 血壓降下, 糖代謝 改善, 肝機能 改善, 腎機能 改善, 혈중 脂質代謝 改善, 免役機能 增强作用이 있으며, 八味地黃丸은 그 외에 Glutathion代謝 影響, 호르몬 影響, 耐寒性 增加, 腦下垂體-副腎皮質機能 改善 等이 있으며, 六味地黃丸은 그 외에 癌誘發 抑制作俑, Interferon 誘導作用 等이 있음을 알 수 있었다. Palmijihwanghan(PJH) and Yukmijihwanghan(YJH) has been widely used as the basic priscriptions for the deficiency of Yin and Yang of kidney. So the study has been carried out to investigate the effects, symptoms, indications and pharmacology of the PJH and YJH. The result of this study were as follows: 1. The effect of PJH is warming and regulation the kidney-Qi and warming and strengthen the kidney-Yang. While the effect of YJH is nourishing the kidney-Yin, nourishing the liver-blood and managing the fire. 2. PJH is used for the treatment of such symptoms caused by dificiency of the kidney-Qi or the kidney-Yang as facial pallidness. dizziness and tinnitus, back pain and leg weakness, cold sensation in lower body, dysuria or urinary frequency, deep and slow or feeble pulse, thirst, edema, persistent diarrhea, painful urination, impotence, dizziness and tinnitus, dry and painful throat, weakness of the teeth, back pain and leg weakness, emmision, thirst, flushed tongue without fur, feeble pulse, dysuria, weakness of the five viscera, spontaneous sweating, perspiration during sleep, and bleeding, which are caused by deficiency of the kidney-Yin or the function of kidney and liver. 3. Both PJH and YJH have been commonly used for treatment of disease of urinary tract disease, hypertension, diabetic mellitus, psychopathy, chronic pulmonary disease. While PJH is applied for the sexual and genital disorders, YJH is for hyperthyrodism, mass in the digestive system and children's malnutrition. 4. The pharmacology of PJH and YJH is commonly the lowering the blood pressure, promoting the glycometabolism, renal function and lipid metabolism, and increasing the immune function. Besides PJH affects on the glutathion metabolism, and hormonal function, increases the cold tolerance ability and improves the function of the pituitary-adrenal cortex, while YJH has the effects of inhibiting the carciogenic action and inducing the interferon secreation.

加味牛膝湯이 實驗動物의 鎭痛에 미치는 影響

金炯均,權文鉉,오로사,金成宰,李彦政,李峰根 圓光大學校 韓醫學硏究所 1996 원광한의학 Vol.6 No.1

잠재오염원을 이용한 포항지역의 광역적 지하수 오염 위험성 평가

이사로 ( Sa Ro Lee ),김용성 ( Yong Seong Kim ),김덕근 ( Dauk Geun Kim ) 한국지리정보학회 2006 한국지리정보학회지 Vol.9 No.3

분심기음(分心氣飮)의 도파민 세포 보호 효과

김로사 ( Ro Sa Kim ),이창훈 ( Chang Hoon Lee ),이진무 ( Jin Moo Lee ),조정훈 ( Jung Hoon Cho ),장준복 ( Jun Bock Jang ),이경섭 ( Kyung Sub Lee ) 대한한방부인과학회 2009 大韓韓方婦人科學會誌 Vol.22 No.2

무용전공 대학생들의 성취목표성향과 무용 참여동기와의 관계

이로사(Ro Sa Lee) 한국무용과학회 2010 한국무용과학회지 Vol.21 No.-

이 연구의 목적은 무용전공 남녀 대학생들의 성취목표성향과 무용 참여동기에 대한 지각과 성취목표성향(과제/자아)과 무용 참여동기 하위요인들(내적/외적/무동기)이 어떠한 관계를 갖고 있는가를 알아보는데 있다. 연구대상은 서울시 소재 대학교에 재학 중인 남녀 무용전공 대학생들(한국무용, 발레, 현대무용)을 모집단으로 설정한 후, 319명(남자: 45명, 여자: 274명)을 무선표집 하였다. 측정도구는 성취목표성향 TEOSQ(Task and Ego Orientation in Sport Questionnaire) 질문지와 참여동기 SMS(Sport Motivation Scale) 질문지를 무용상황에 맞게 수정 보완하여 사용하였다. 자료분석은 성별에 따른 성취목표성향의 평균비교(t-검증)와 무용 참여동기(내적, 외적, 무동기)차이를 알아보는 다변량분산분석(one-way MANOVA), 그리고 성취목표성향과 무용 참여동기 하위요인들의 관계성은 단순 상관관계와 정준 상관성(canonical correlation)분석을 사용하였다. 연구결과 무용전공 대학생들의 성취목표성향은 성별에 따라 차이를 나타냈다. 여자 대학생들이 남자 대학생들보다 높은 과제지향성을 나타내었고, 남자 대학생들은 여자 대학생들보다 높은 자아지향성을 보여주었다. 무용 참여동기에 대한 연구결과에서도 성별에 따른 차이를 보였다. 참여동기의 하위요인들(내적동기, 외적동기, 무동기) 모두 여자 대학생들이 남자 대학생들 보다 높은 동기수준을 나타내었고, 무용전공 대학생들의 과제 지향성은 무용 참여동기의 하위요인들(내적동기, 외적동기, 무동기)과 상관관계를 보였다. The purpose of this study examined the relationship between an goal perspective(i.e., task or ego orientation) and perception of the motivation of university students majoring in dancing and the low-level factors of the participation(intrinsic/extrinsic/none). The subjects were 319(male students: 45; female students: 274) who are practicing dance (Korean Dance, Ballet and Modern Dance) at universities in Seoul and they were randomly selected. The subjects's goal orientations (task and ego) in this study were measured by Korean version of the Task and Ego Orientation in Sport Questionnaire(KTEOSQ) and the motivation of participation in dance is measured by the revised questionnaire of Sport Motivation Scale (SMS). The T-analysis is used in analyzing the differences of achievement goal orientation by sex and one-way MANOVA for explaining sexual differences in the motivation is used. As for the correlation between the achievement goal orientation and underlying factors is analyzed by the correlation and canonical correlation analysis. Results indicated that female students were significantly higher in task orientation than males students, while male students were significantly higher in ego orientation than females students. The result of the study on the motivation of participation also shows the sexual differences. Female students who are majoring in dance at universities show higher level of motivation in all the factors underlying the motivation(intrinsic/extrinsic/none) and it is showed that the Task-orientedness is collated with these factors.

Pub Med 검색을 통한 폐경기 증상의 침구 임상시험에 대한 고찰 -안면홍조를 중심으로

김로사 ( Ro Sa Kim ),이진무 ( Jin Moo Lee ),이창훈 ( Chang Hoon Lee ),조정훈 ( Jung Hoon Cho ),장준복 ( Jun Bock Jang ),이경섭 ( Kyung Sub Lee ) 대한한방부인과학회 2007 大韓韓方婦人科學會誌 Vol.20 No.4

Using Internet Video Clips for University Students` Vocabulary Development in Blended Learning

( Ro Sa Jung ),( Chung Hyun Lee ) 한국멀티미디어언어교육학회 2013 멀티미디어 언어교육 Vol.16 No.4

The purposes of the study are to investigate the impact of using video clips on university students` vocabulary development via listening in blended learning and to suggest a vocabulary instructional model for the use of video clips in blended learning. Twenty one students participated in L2 listening classes at A university in Seoul. A combination of qualitative data from students` reflective journals, classroom observations, and interviews and quantitative data from pre- and post- vocabulary tests, performance assessment, and a questionnaire was collected. The major findings of the study are as follows. First, about 55% of the students guessed the meaning of the words with visual, contextual, and verbal clues from video clips. Second, the students` overall perspectives on using video clips for learning vocabulary in blended learning were very positive. Third, the students had generally positive perspectives on online and offline activities. Guessing the meaning of the words and filling out the summary were the most preferred offline and online activities, respectively. Finally, the students` vocabulary test scores increased indicating that using video clips in blended learning had positive effects on students` vocabulary development. Based on the findings, a vocabulary instructional model as well as implications are provided.

Production of Monoclonal Antibody to Oxytocin for Immunohistochemical Use

Lee, Seung Ro,Cho, Sa Sun Seoul National University 1986 The seoul journal of medicine Vol.27 No.1

A case of giant cell tumor of tendon sheath

( Ro Sa Kim ),( Bo Ram Kwon ),( Hae Young Choi ),( You Won Choi ),( Min Young Lee ),( Ji Yeon Byun ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1

Giant cell tumor of tendon sheath (GCTTS) is a second most common tumor of the hand following the ganglion cyst. It presents a slowly growing subcutaneous nodule in the finger encapsulated by a collagenous capsule. GCTTS has benign course mostly with diagnosed as a localized form, but rare cases of malignant GCTTS have been reported. As incomplete excision increases recurrence rate and on recurrence the possibility of malignant transformation also increases. The average age of onset of GCTTS is middle-aged adults and the prevalent site is the volar surface of finger. An 85-year-old Korean female presented with skin colored hard nodule on dorsal surface of left 3rd DIP joint of finger, a slowly enlarging for several years. Histological examination showed a well encapsulated round lobule in the dermis with varied cellularity. The mass consisted of many mononuclear cells and spindle cells in fibrous stroma, and osteoclast-like giant cells and foamy macrophages were characteristic. There was no specific finding in the Von-Kossa stain and the level of serum uric acid was normal. The patient was diagnosed with GCTTS and referred to an orthopedic surgeon for an excision surgery. Herein, we report a rare case of GCTTS occurring in old age on dorsal surface of finger.

고온 알칼리 내성 균주인 Bacillus pumilus의 cytidine deaminase를 코드하는 cdd 유전자의 cloning

김로사,이상만 청주대학교 산업과학연구소 1997 産業科學硏究 Vol.15 No.-

A thermo-alkalotolerant strain was screened from a hot spring and the cdd gene encoding cytidine deaminase of the stram was cloned in E. coli. The isolated strain was grown up to 60 C and pH 11.0. The colony was bright yellow and hilly elevation with lobate margin on LB agar plate. The characteristics of the strain was as follow : aerobic, gram positive, formation of the endospore, rod type. The cell size was 0.4-0 5 X 1.4-1.7㎛. The isolated strain was identified as Bacillus pumilus of its close relative on the basis of the cultural, morphological and physiological experiments. The cdd gene of the isolated strain was cloned to the pBR 322 and transformed to E. coli JF 611. The result was that the 3.2kb fragment containing cdd gene was inserted EcoRI site of the pBR 322. XhoI and PstI restriction site was shown in the fragment of 3.2kb according to the restriction mapping.