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RAM(Range Adjusted Measure)을 이용한 부품소재 기업들의 생산성 분석 및 R&D 현황에 관한 실증연구
이정동,백철우,이운규 한국생산성학회 2004 生産性論集 Vol.18 No.2
Increased global sourcing and reorganization in high value-added-centered industries make parts and material industry, which forms 46% of total production and 40% of total exports in manufacturing sector, more important. In a sense that parts and material industry is . vulnerable in spite of its consequence, a lot of policy support was given. Parts and material industry, however, has never been researched empirically in firm level, therefore in this research we would like to analyze the competitiveness of parts and material firms compared with manufacturing sector, and to inquire into their current R&D position. Consequently, we suggest how to make value-added products more efficiently through R&D.
진딧물의 경보페로몬인 (E)-β-Farnesene의 합성과 생물활성시험
강석구,정경운,이정운,고현관 성균관대학교 기초과학연구소 1986 論文集 Vol.37 No.1
(E)-β-Farnesene, the alarm pheromone of aphids was synthesized from nerolidol by reacting in a sealed tube at 150℃ for 24h with DMSO. Base(KOtBu/DMSO) catalized elimination of HCl from farnesyl chloride at 50℃ for 4h afforded (E)-β-farnesene as the major product. Farnesyl chloride was prepared from nerolidol or farnesol with SOCl_2 or HCl. Biological activity test of (E)-β-farnesene thus synthesized was conducted.
Late Presentation into Care of HIV Disease and Its Associated Factors in Asia: Results of TAHOD
Jeong, Su Jin,Italiano, Claire,Chaiwarith, Romanee,Ng, Oon Tek,Vanar, Sasheela,Jiamsakul, Awachana,Saphonn, Vonthanak,Nguyen, Kinh Van,Kiertiburanakul, Sasisopin,Lee, Man Po,Merati, Tuti Parwati,Pham, MARY ANN LIEBERT INC PUBL 2016 AIDS RESEARCH AND HUMAN RETROVIRUSES Vol.32 No.3
Phytophthora species 의 분자유전학적 분류 및 RAPD fingerprinting 을 이용한 P . infestans - specific 분자마커의 선발
이민웅,김경수,신환성,김희종,우수진,함영일,신관용,이정운,김병섭,심재욱,이윤수 한국균학회 1999 韓國菌學會誌 Vol.27 No.6
Taxonomic and genetic analysis of Phytophthora species belonging to six different morphological groups (GI, GII, GIII, GIV, GV, GVI) was conducted using RAPD method. Amplified fragments ranged 0.3∼3.2 kb in their molecular weights. Among total of 145 bands, there were 109 polymorphic bands Seven isolates of P. infestans showed high similarities of 0.92∼0.99, and P. infestans isolate 3 from potato showed similarities of 0.93∼0.95 compared with other P. infestans. Among isolates of P. capsici, similarities of 0.77∼0.86 were observed and they were grouped in 80% level. P. cinnamomi and P. cryptogea isolates which belonging to group GVI showed very similar RAPD fingerprinting pattern. Primers OPA-04, OPA-17, OPA-18, OPA-19, and OPB-12 showed high level of differences among the tested isolates in major bands and molecular weights. The similarity between the isolates was 0.67. P. megasperma and P. sojae in group GV showed similarity of 0.65. These two isolates showed big differences in single major band in reactions with primers OPA-08, OPA-17, and OPA-19. Phytophthora-specific and P. infestans-specific molecular markers were also selected with one of the random primers tested. In reaction with primer OPA-20, all the genus Phytophthora showed common band at 600 bp, and all the P. infestans isolates showed specific band at 680 bp. These markers can be useful far identification of Phytophthora speices or P. infestans. As a result, P. infestans isolated from tomato and/or potato can easily be differentiated from other Phytophthora species with this primer.
CD21-independent Epstein-Barr virus entry into NK cells
Lee, Jeong Hoo,Choi, Jahyang,Ahn, Yong-Oon,Kim, Tae Min,Heo, Dae Seog Elsevier 2018 Cellular immunology Vol.327 No.-
<P><B>Abstract</B></P> <P>Extranodal natural killer (NK)/T-cell lymphoma is an aggressive malignant disease that is associated with Epstein-Barr viral (EBV) infection. To date, the mechanism of viral entry into NK cells remains uncertain. Here, we investigated this mechanism using human NK cells <I>in vitro</I>. CD21 mRNA expression, an EBV-entry receptor, was transiently detected in NK cells after exosome treatment, and levels decreased after further culture. CD21 protein expression was also transiently transferred to NK cells after co-culture with an EBV-positive Burkitt lymphoma cell line (Raji) via trogocytosis. However, EBV did not infect NK cells through CD21-mediated trogocytosis. Unexpectedly, when NK cell leukemia cells, as well as primary NK cells, were treated with viral supernatant, EBV genes, but not RNA, were detected in the NK cells, at latency stage 0. Therefore, these results suggest that EBV-NK cell infection results from the direct transfer of viral episomes, independent of EBV-positive B cells.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Transfer of EBV RNA in exosomes from the EBV-infected B cells to NK cells is transient. </LI> <LI> Trogocytosis of CD21, an entry receptor for EBV is not an NK infection mechanism. </LI> <LI> EBV viral episomes can be transferred into NK cells, without EBV-positive B cells. </LI> </UL> </P>