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- 저자 : Labibi, Farzaneh (검색결과 3 건)
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Experimental and Numerical Study of Pyramidal Steel Damper for Use in Frames with Diagonal Bracing
Hossein Labibi,Mohsen Gerami,Mahmood Hosseini 한국강구조학회 2022 International Journal of Steel Structures Vol.22 No.5
Convergent bracing system has long been considered by structural designers. However, the performance of this system during an earthquake has disadvantages such as high base shear and low energy absorption due to buckling of the braces. Thus, researchers have tried to improve the behavior of the structure by proposing the use of diff erent dampers in the lateral bearing section. Meanwhile, yielding dampers as low-cost dampers with easy manufacturing technology compared to visco-elastic and non-buckling dampers have always attracted the attention of researchers. However, the proposed designs have generally a one-level behavior and the yielding members cause instability of the frame in the case of the failure. Accordingly, in this research, a new type of steel yielding damper with multi-level performance has been introduced, in which the fl exural yield of the parallel trapezoidal plates has been used for the energy absorption process. Also, to ensure the stability of the braced frame in severe earthquakes, a simple support system has been included in its design. The damper has a pyramidal core that can be adjusted for stiff ness and functional levels based on the seismic requirements of the frame. To perform this research, while performing fi nite element modeling, the relevant specimens were made and subjected to cyclic loading experimental tests. Also, a comparative nonlinear time history analyses on a seven story CBF frame has been done. The results indicated the appropriate and stable cyclic behavior of the two-level pyramidal damper, tolerance of cumulative displacements of about 2000 mm, absorption of a signifi cant energy of 50 kJ and signifi cant improvement in time history responses. Finally, multi-line behavior curve and a capacity chart of the damper is presented.
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Zanjani, Taraneh Moini,Ameli, Haleh,Labibi, Farzaneh,Sedaghat, Katayoun,Sabetkasaei, Masoumeh The Korean Pain Society 2014 The Korean Journal of Pain Vol.27 No.3
Background: Neuropathic pain is generally defined as a chronic pain state resulting from peripheral and/or central nerve injury. There is a lack of effective treatment for neuropathic pain, which may possibly be related to poor understanding of pathological mechanisms at the molecular level. Curcumin, a therapeutic herbal extract, has shown to be effectively capable of reducing chronic pain induced by peripheral administration of inflammatory agents such as formalin. In this study, we aimed to show the effect of curcumin on pain behavior and serum COX-2 level in a Chronic Constriction Injury (CCI) model of neuropathic pain. Methods: Wistar male rats (150-200 g, n = 8) were divided into three groups: CCI vehicle-treated, sham-operated, and CCI drug-treated group. Curcumin (12.5, 25, 50 mg/kg, IP) was injected 24 h before surgery and continued daily for 7 days post-surgery. Behavioral tests were performed once before and following the days 1, 3, 5, 7 after surgery. The serum COX-2 level was measured on day 7 after the surgery. Results: Curcumin (50 mg/kg) decreased mechanical and cold allodynia (P < 0.001) and produced a decline in serum COX-2 level (P < 0.001). Conclusions: A considerable decline in pain behavior and serum COX-2 levels was seen in rat following administration of curcumin in CCI model of neuropathic pain. High concentration of Curcumin was able to reduce the chronic neuropathic pain induced by CCI model and the serum level of COX-2.
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( Taraneh Moini Zanjani ),( Haleh Ameli ),( Farzaneh Labibi ),( Katayoun Sedaghat ),( Masoumeh Sabetkasaei ) 대한통증학회 2014 The Korean Journal of Pain Vol.27 No.3
Background: Neuropathic pain is generally defined as a chronic pain state resulting from peripheral and/or central nerve injury. There is a lack of effective treatment for neuropathic pain, which may possibly be related to poor understanding of pathological mechanisms at the molecular level. Curcumin, a therapeutic herbal extract, has shown to be effectively capable of reducing chronic pain induced by peripheral administration of inflammatory agents such as formalin. In this study, we aimed to show the effect of curcumin on pain behavior and serum COX-2 level in a Chronic Constriction Injury (CCI) model of neuropathic pain. Methods: Wistar male rats (150-200 g, n = 8) were divided into three groups: CCI vehicle-treated, sham-operated, and CCI drug-treated group. Curcumin (12.5, 25, 50 mg/kg, IP) was injected 24 h before surgery and continued daily for 7 days post-surgery. Behavioral tests were performed once before and following the days 1, 3, 5, 7 after surgery. The serum COX-2 level was measured on day 7 after the surgery. Results: Curcumin (50 mg/kg) decreased mechanical and cold allodynia (P < 0.001) and produced a decline in serum COX-2 level (P < 0.001). Conclusions: A considerable decline in pain behavior and serum COX-2 levels was seen in rat following administration of curcumin in CCI model of neuropathic pain. High concentration of Curcumin was able to reduce the chronic neuropathic pain induced by CCI model and the serum level of COX-2.
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