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Kwon Hyeonsoo,Kim Jimin,Bang Minjun,Bae Jaewon,Oh Byunghyun,Kim Hongik,Jung Sehun,Ryu Myungseok 대한침도의학회 2023 대한침도의학회지 Vol.7 No.2
Introduction: The purpose of this study is to provide anatomical information of BL40 in- cluding applicable needling depth, bloodletting methods and related physiological effect. Methods: The contents about BL40 were extracted from literature. Then we investigated the clinical effect, needling feature (depth/angle/stimulation method) and the bloodlet- ting methods of BL40, searching online databases like ‘RISS’, ‘Oasis’, ‘DBPIA’, ’Naver Aca- demic information’, ‘National Research institute of Korea’, ‘Pubmed’, ‘Google scholar’ and ‘CNKI’ from 1990 to 2023. Results: According to the classic test, the needling depth of BL40 is 9.35-33.15 mm, that of previous research is 9.4 mm-23.4 mm. When acupuncture is applied at that level, stim- ulatable anatomical structures were deep popliteal fascia and tibial nerve. Conclusion: The remarkable effect of BL40 is originated from stimulation of deep popli- teal fascia and tibial nerve. It is necessary for BL40 to be stimulated as 15.5 mm depth.
HGTree: database of horizontally transferred genes determined by tree reconciliation
Jeong, Hyeonsoo,Sung, Samsun,Kwon, Taehyung,Seo, Minseok,Caetano-Anollé,s, Kelsey,Choi, Sang Ho,Cho, Seoae,Nasir, Arshan,Kim, Heebal Oxford University Press 2016 Nucleic acids research Vol.44 No.d1
<P>The HGTree database provides putative genome-wide horizontal gene transfer (HGT) information for 2472 completely sequenced prokaryotic genomes. This task is accomplished by reconstructing approximate maximum likelihood phylogenetic trees for each orthologous gene and corresponding 16S rRNA reference species sets and then reconciling the two trees under parsimony framework. The tree reconciliation method is generally considered to be a reliable way to detect HGT events but its practical use has remained limited because the method is computationally intensive and conceptually challenging. In this regard, HGTree (http://hgtree.snu.ac.kr) represents a useful addition to the biological community and enables quick and easy retrieval of information for HGT-acquired genes to better understand microbial taxonomy and evolution. The database is freely available and can be easily scaled and updated to keep pace with the rapid rise in genomic information.</P>