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Kotla, Anuradha,Agarwa, Surekha,Yadavalli, Venkateswara Rao,Vinukonda, Vishnu Prasanth,Dhavala, V.N. Chakravarthi,Neelamraju, Sarla 한국작물학회 2013 Journal of crop science and biotechnology Vol.16 No.1
Yield of popular rice varieties such as Swarna grown in rainfed lowlands and Madhukar grown in flood prone areas needs to be continuously improved. Recombinant inbred lines (RILs) were developed from the cross between two indica cultivars Madhukar and Swarna. QTLs were mapped using 110 markers in 168 RILs. In all, 26 QTLs were mapped for yield and five related traits on chromosomes 1, 2, 3, 6, 7, 8, 10, 11, and 12. QTL for plant height and days to flowering were co-located between RM23147 - RM337 on chromosome 8. RM251, RM314, and RM1135 were significantly associated with plant height and OsYSL17 was significantly linked with grain yield. Epistatic interaction was detected for plant height and number of tillers. Several candidate genes reported for yield and related traits underlie the QTL regions.
Anuradha Kotla,Sarla Neelamraju,Surekha Agarwal,Venkateswara Rao Yadavalli,Vishnu Prasanth Vinukonda,VN Chakravarthi Dhavala 한국작물학회 2013 Journal of crop science and biotechnology Vol.16 No.1
Yield of popular rice varieties such as Swarna grown in rainfed lowlands and Madhukar grown in flood prone areas needs to be continuously improved. Recombinant inbred lines (RILs) were developed from the cross between two indica cultivars Madhukar and Swarna. QTLs were mapped using 110 markers in 168 RILs. In all, 26 QTLs were mapped for yield and five related traits on chromosomes 1, 2, 3, 6, 7, 8, 10, 11, and 12. QTL for plant height and days to flowering were co-located between RM23147 - RM337 on chromosome 8. RM251, RM314, and RM1135 were significantly associated with plant height and OsYSL17 was significantly linked with grain yield. Epistatic interaction was detected for plant height and number of tillers. Several candidate genes reported for yield and related traits underlie the QTL regions.
Per Oral Endoscopic Myotomy in Children with Achalasia Cardia
( Zaheer Nabi ),( Mohan Ramchandani ),( D Nageshwar Reddy ),( Santosh Darisetty ),( Rama Kotla ),( Rakesh Kalapala ),( Radhika Chavan ) 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2016 Journal of Neurogastroenterology and Motility (JNM Vol.22 No.4
Background/Aims Achalasia cardia (AC) is a motility disorder, characterized by impaired lower esophageal sphincter relaxation and absence of esophageal peristalsis. AC is rare in children with unclear optimum management strategies. Per oral endoscopic myotomy (POEM) is a novel technique for management of achalasia with encouraging results in adult patients. The efficacy and safety of POEM is not known for pediatric AC. The aim of our study was to evaluate the safety and efficacy of POEM in children with achalasia cardia Methods The data of all children (< 18 years) who underwent POEM at our center was retrospectively analysed. Symptoms were analysed using a validated score (Eckardt score) at regular predefined intervals. Objective parameters including high-resolution manometry, timed barium swallow and esophagogastroduodenoscopy were assessed before the procedure and at 1-year follow-up. Clinical success was defined as an Eckardt score ≤ 3. Results A total of 15 children underwent POEM during the specified period. Ten out of 15 (10/15) completed 1-year follow-up. Median operative time was 100 (38-240) minutes. Mean pre and post procedure LES pressure were 36.64 ± 11.08 mmHg and 15.65 ± 5.73 mmHg, respectively (P = 0.001). Mean Eckardt score before and after the POEM was 7.32 ± 1.42 and 1.74 ± 0.67, respectively (P = 0.001). Mean percentage improvement in barium emptying at 5 minutes was 63.70 ± 4.46%. All children had complete resolution of symptoms at 1 year. Median weight gain of children at 1 year was 0.65 kg (range, 0.0-4.6). Conclusions POEM is safe and effective for children and adolescents with achalasia. Future trials with larger sample size are warranted to establish its efficacy in pediatric AC.