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        Prediction of bed pressure drop and top packed bed formation in gas-liquid-solid semi-fluidized bed with irregular homogeneous binary mixtures

        Deepak Kumar Samal,Yashobanta Kumar Mohanty,Gopendra Kishore Roy 한국화학공학회 2013 Korean Journal of Chemical Engineering Vol.30 No.6

        We studied the hydrodynamics of a gas-liquid-solid semi-fluidized bed relating to packed bed formation and bed pressure drop with irregular homogeneous binary mixtures in a 0.05 m internal diameter Perspex column, with water and air (secondary) as fluidizing medium at constant static bed height of 0.08 m. A homogeneous binary mixture has been taken for easy formation of a semi-fluidized bed. Air is supplied centrally below the bottom grid in radial direction with a special design air sparger after the bed is first fluidized by the liquid. Experimental parameters studied included superficial gas and liquid velocities, average particle size and density and the bed expansion ratio. Empirical and semi-empirical models were developed. The calculated values from predicted models were compared with the experimental values and fairly good agreement was obtained.

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        Cardiovagal Barorefex Sensitivity in Parkinson’s Disease and Multiple-System Atrophy

        Sankanika Roy,Ashok Kumar Jaryal,Achal Kumar Srivastava,Kishore Kumar Deepak 대한신경과학회 2016 Journal of Clinical Neurology Vol.12 No.2

        Background and Purpose Parkinson’s disease (PD) and multiple-system atrophy of the parkinsonian type (MSA-P) are progressive neurodegenerative disorders that in addition to dysfunction of the motor system also present with features of dysautonomia, frequently manifesting as orthostatic hypotension (OH). Te pathophysiology of OH has been proposed to difer between these two disorders. Tis study investigated the spontaneous and cardiovagal barorefex sensitivity (BRS) in Parkinson’s disease patients with orthostatic hypotension (PDOH ) and multiple system atrophy of Parkinsonian type with orthostatic hypotension in an attempt to diferentiate the two disorders. Methods Two methods were used for determining the BRS: a spontaneous method (spontaneous BRS) and the refexive barorefex gain (cardiovagal BRS) from phases II and IV of the Valsalva maneuver (VM) in PDOH and MSA-POH . Results The spontaneous BRS (5.04±0.66 ms/mm Hg vs. 4.78±0.64 ms/mm Hg, p=0.54) and the cardiovagal BRS from phase II of the VM (0.96±0.75 ms/mm Hg vs. 1.34±1.51 ms/mm Hg, p=0.76) did not difer between PDOH and MSA-POH , but the cardiovagal BRS from phase IV of the VM (0.03±0.07 ms/mm Hg vs. 2.86±2.39 ms/mm Hg, p=0.004) was signifcantly lower in PDOH . Conclusions Te cardiovagal BRS from phase IV of the VM has potential for diferentiating PDOH and MSA-POH , indicating a diference in the pathophysiological mechanisms underlying the autonomic dysfunction in the two disorders.

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