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      • An Electronic Strategy in Innovative Learning Situations and the Design of a Digital Application for Individual Learning to Combat Deviant Intellectual Currents in Light of the Saudi Vision 2030

        Aisha Bleyhesh, Al-Amri,Khaloud, Zainaddin,Abdulrahman Ahmed, Zahid,Jehan, Sulaimani International Journal of Computer ScienceNetwork S 2022 International journal of computer science and netw Vol.22 No.12

        The study aimed to build an electronic strategy in innovative learning situations for the role of education in combating intellectual currents. A total of 525 Saudi university faculty members and general education teachers were surveyed using two electronic questionnaires. Arithmetic averages and standard deviations, One-way ANOVA, Scheffé's test, Pearson's correlation coefficient, and Cronbach's alpha stability coefficient were used as statistical methods. The study statistically identifies the differences between the study sample at the level of significance (0.05). and the design of a digital application for individual learning to combat deviant intellectual currents to activate them in light of Saudi Vision 2030 by combining the theoretical academic material and turning it into a learning e-game called (crosswords). The game is equipped with hyper media that supports education with entertainment to direct ideas towards the promotion of identity, the development of values towards moderation and the consolidation of intellectual security. Additionally, the learning e-game represents awareness messages in three short films to activate the role of curricula and intellectual awareness centers to apply realistically, innovatively, and effectively.

      • SCIESCOPUS

        Strength and durability characteristics of biopolymer-treated desert sand

        Qureshi, Mohsin U.,Chang, Ilhan,Al-Sadarani, Khaloud Techno-Press 2017 Geomechanics & engineering Vol.12 No.5

        Biopolymer treatment of geomaterials to develop sustainable geotechnical systems is an important step towards the reduction of global warming. The cutting edge technology of biopolymer treatment is not only environment friendly but also has widespread application. This paper presents the strength and slake durability characteristics of biopolymer-treated sand sampled from Al-Sharqia Desert in Oman. The specimens were prepared by mixing sand at various proportions by weight of xanthan gum biopolymer. To make a comparison with conventional methods of ground improvement, cement treated sand specimens were also prepared. To demonstrate the effects of wetting and drying, standard slake durability tests were also conducted on the specimens. According to the results of strength tests, xanthan gum treatment increased the unconfined strength of sand, similar to the strengthening effect of mixing cement in sand. The slake durability test results indicated that the resistance of biopolymer-treated sand to disintegration upon interaction with water is stronger than that of cement treated sand. The percentage of xanthan gum to treat sand is proposed as 2-3% for optimal performance in terms of strength and durability. SEM analysis of biopolymer-treated sand specimens also confirms that the sand particles are linked through the biopolymer, which has increased shear resistance and durability. Results of this study imply xanthan gum biopolymer treatment as an eco-friendly technique to improve the mechanical properties of desert sand. However, the strengthening effect due to the biopolymer treatment of sand can be weakened upon interaction with water.

      • KCI등재

        Antimicrobial Efficacy of Allium cepa and Zingiber officinale Against the Milk-Borne Pathogen Listeria monocytogenes

        Arasu Abirami,Prabha Nagaram,Devi Durga,Issac Praveen Kumar,Alarjani Khaloud Mohammed,Al Farraj Dunia A.,Aljeidi Reem A.,Tayyeb Jehad Zuhair,Guru Ajay,Arockiaraj Jesu,Mohan Magesh,Hussein Dina S. 한국미생물학회 2023 The journal of microbiology Vol.61 No.11

        Listeria monocytogenes is an important food-borne pathogen that causes listeriosis and has a high case fatality rate despite its low incidence. Medicinal plants and their secondary metabolites have been identified as potential antibacterial substances, serving as replacements for synthetic chemical compounds. The present studies emphasize two significant medicinal plants, Allium cepa and Zingiber officinale, and their efficacy against L. monocytogenes. Firstly, a bacterial isolate was obtained from milk and identified through morphology and biochemical reactions. The species of the isolate were further confirmed through 16S rRNA analysis. Furthermore, polar solvents such as methanol and ethanol were used for the extraction of secondary metabolites from A. cepa and Z. officinale. Crude phytochemical components were identified using phytochemical tests, FTIR, and GC–MS. Moreover, the antibacterial activity of the crude extract and its various concentrations were tested against L. monocytogenes. Among all, A. cepa in methanolic extracts showed significant inhibitory activity. Since, the A. cepa for methanolic crude extract was used to perform autography to assess its bactericidal activity. Subsequently, molecular docking was performed to determine the specific compound inhibition. The docking results revealed that four compounds displayed strong binding affinity with the virulence factor Listeriolysin-O of L. monocytogenes. Based on the above results, it can be concluded that the medicinal plant A. cepa has potential antibacterial effects against L. monocytogenes, particularly targeting its virulence.

      • KCI등재

        Furan-based Chalcone Annihilates the Multi-Drug-Resistant Pseudomonas aeruginosa and Protects Zebra Fish Against its Infection

        Nayak Santosh Pushpa Ramya Ranjan,Basty Catharine,Boopathi Seenivasan,Dhivya Loganathan Sumathi,Alarjani Khaloud Mohammed,Gawwad Mohamed Ragab Abdel,Hager Raghda,Kathiravan Muthu Kumaradoss,Arockiaraj 한국미생물학회 2024 The journal of microbiology Vol.62 No.2

        The emergence of carbapenem-resistant Pseudomonas aeruginosa, a multi-drug-resistant bacteria, is becoming a serious public health concern. This bacterium infects immunocompromised patients and has a high fatality rate. Both naturally and synthetically produced chalcones are known to have a wide array of biological activities. The antibacterial properties of synthetically produced chalcone were studied against P. aeruginosa. In vitro, study of the compound (chalcone derivative named DKO1), also known as (2E)-1-(5-methylfuran-2-yl)-3-(4-nitrophenyl) prop-2-en-1-one, had substantial antibacterial and biofilm disruptive action. DKO1 effectively shielded against P. aeruginosa-induced inflammation, oxidative stress, lipid peroxidation, and apoptosis in zebrafish larvae. In adult zebrafish, the treatment enhanced the chances of survivability and reduced the sickness-like behaviors. Gene expression, biochemical analysis, and histopathology studies found that proinflammatory cytokines (TNF-α, IL-1β, IL-6, iNOS) were down regulated; antioxidant enzymes such as superoxide dismutase (SOD) and catalase (CAT) levels increased, and histoarchitecture was restored in zebrafish. The data indicate that DKO1 is an effective antibacterial agent against P. aeruginosa demonstrated both in vitro and in vivo.

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