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A case of solitary Langerhans cell histiocytosis
( Jee Yon Shin ),( Myeong Heon Chae ),( Ji Yeoun Lee ),( Tae Young Yoon ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1
Langerhans cell histiocytosis is caused by infiltration of the skin, and in some cases, other organs, by Langerhans cells. The spectrum of disease is broad. It can be presented with a solitary lesion and also presented with visceral and skin involvement. In childhood LCH, boys are slightly more often affected than girls. About 10% of children have single-organ disease involving only the skin, and 50% of children with multisystem LCH have skin involvement. A 17-year-old girl presented with solitary brownish nodule on the abdomen. It was occurred 3~4 months ago. Itching sense was mild and size change was not prominent. Histopathologic findings showed dermal infiltrate of Langerhans cells. On the immunohistochemistry, S-100 and CD1a was positive. There was no other skin lesion and no other organ involvement. Based on these findings, a diagnosis of solitary Langerhans cells histiocytosis was made. Herein, we report a rare case of solitary Langerhans cell histiocytosis in the Korean literatures.
A clinical and histopathological review of sweet syndrome in Korean children and adolescents
( Jee Yon Shin ),( Ji Yeoun Lee ),( Tae Young Yoon ) 대한피부과학회 2020 대한피부과학회 학술발표대회집 Vol.72 No.1
Background: Sweet syndrome is characterized by tender erythematous plaques and nodules. Sweet syndrome is relatively rare in children and adolescents. Until date, only a few cases have been reported in the Korean literature. Objectives: The aim of this study is to investigate the clinical and histopathological features of Sweet syndrome in Korean children and adolescents. Methods: A retrospective study was conducted on 15 pediatric patients (< 18 years) who were diagnosed with Sweet syndrome between 1991 and 2019. We reviewed the clinical and histopathological features of Sweet syndrome. Results: The age of 15 patients ranged from 4 months to 17 years. Among the 15 Sweet syndrome patients, nine patients were females and six patients were males. Most of the patients had lesions on the upper extremities. Fever and tenderness were the most common associated symptoms. Transient infection such as upper respiratory infection or gastroenteritis was the most common identifiable cause, observed in 40% of the patients. Histopathologically dermal neutrophilic infiltration was observed in all the patients. All patients were treated with systemic corticosteroid and showed good response although 26.7% of the patients experienced recurrences. Conclusion: Contrast to the previous reports of pediatric Sweet syndrome, female predominance was observed in this study. As a preceding factor, transient infection was the most common. All patients responded well to systemic corticosteroid therapy.
A case of subcutaneous granuloma annulare on the thigh in an elderly.
( Jee Yon Shin ),( Myeong Heon Chae ),( Su Hyun Park ),( Ji Yeoun Lee ),( Tae Young Yoon ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1
Granuloma annulare (GA) is a benign granulomatous disease of unknown etiology. Subcutaneous GA is a type of GA presented as asymptomatic firm and hard subcutaneous nodules. The predominant site of subcutaneous GA is the anterior lower leg, and it also appears on the ankles, dorsal feet, buttocks, and hands. Generally, subcutaneous GA is occurred in children. A 73-year-old woman presented with a brownish nodule on the right thigh for 2 years. Histopathologic findings showed histiocytic palisades surrounding mucin and degenerated collagen in the subcutaneous tissue. Based on these findings, a diagnosis of subcutaneous GA was made. Herein, we report a rare case of subcutaneous type GA on the thigh which was occurred in the old age.
Two cases of lichen striatus in adults
( Jee Yon Shin ),( Myeong Heon Chae ),( Su Hyun Park ),( Ji Yeoun Lee ),( Tae Young Yoon ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1
Lichen striatus is a fairly uncommon dermatosis manifests as linear and papular eruptiondistributed along with Blaschko’s line. As a rule, it occurs in children from 5 to 15 years of age. We present two cases of lichen striatus occurred in adults. The first case is a 37-year-old man who presented with brownish linear papules on the trunk and left lower leg occurred about 4 months ago. The second case is a 29-year-old woman who presented with a linear brownish papules on the right lower leg occurred about 1 year ago. Histopathologic findings showed lichenoid, lymphocytic infiltrate in the papillary dermis with vacuolar degeneration of the basal layer, and periadnexal inflammatory infiltrate in the reticular dermis in the both cases. Based on these findings both of them were diagnosed with lichen striatus. Herein, we report two cases of lichen striatus occurred in adults which is rarely reported in the Korean literature.
A case of lichen amyloidosis in an adult
( Jee Yon Shin ),( Myeong Heon Chae ),( Ji Yeoun Lee ),( Tae Young Yoon ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1
Lichen amyloidosis is a type of primary localized cutaneous amyloidosis clinically characterized by persistent pruritic, hyperkeratotic papules commonly distributed on the shins. Histopathologically, amyloid deposition in the papillary dermis is the characteristic finding. It appears to be more common in males and most often occurs in people 50-60 years of age. A 49-year-old woman presented with brownish papuloplaques on the both lower legs. Itching sense was severe and the lesion was occurred 2 years ago. Histopatholgic findings showed amyloid deposit in the papillary dermis. D-PAS staining was negative. Based on these findings, a diagnosis of lichen amyloidosis was made. We think this case has typical chracteristics of lichen amyloidosis. Therefore we report a case of lichen amyloidosis for educational purposes.
A case of lupus erythematous panniculitis
( Jee Yon Shin ),( Myeong Heon Chae ),( Ji Yeoun Lee ),( Tae Young Yoon ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.1
Lupus panniculitis of the scalp is a rare presentation of lupus erythematous panniculitis. Lupus panniculitis of the scalp has the distinctive clinical feature of distribution along the lines of Blaschko, giving rise to linear, arched or annular alopecia. A 24-year-old man presented with linear alopecic patches on the scalp. It was occurred 7 years ago. He had received triamcinolone acetate intralesional injection 2 times when the lesion was occurred. But he stopped the treatment meanwhile. Histopathologic findings showed lymphoplasmacytic infiltration of the perifollicular dermis and subcutaneous lobules with abundant mucin deposition. Laboratory findings including CBC, chemistry, liver function test, urinalysis, ANA titer, C3, and C4 were normal and negative. Based on these findings, a diagnosis of lupus erythematous panniculitis was made. Herein, we report a rare case of lupus erythematous panniculitis on the scalp.
소아청소년에서 발생한 Sweet 증후군 15예에 대한 임상 및 병리조직학적 고찰
신지연 ( Jee Yon Shin ),이지연 ( Ji Yeoun Lee ),윤태영 ( Tae Young Yoon ) 대한피부과학회 2021 대한피부과학회지 Vol.59 No.3
Background: Sweet syndrome is characterized by tender erythematous plaques and nodules with predominantly dermal neutrophilic infiltrates. Sweet syndrome is relatively rare in children and adolescents. To date, only a few cases have been reported in Korean literature. Objective: The aim of this study was to investigate the clinical and histopathological features of Sweet syndrome in Korean children and adolescents. Methods: A retrospective study was conducted on 15 pediatric patients (aged <18 years) who were diagnosed with Sweet syndrome between 1991 and 2019. We reviewed the clinical and histopathological features of Sweet syndrome. Results: The age of the 15 patients ranged from 4 months to 17 years. Among the 15 patients with Sweet syndrome, nine patients were females and six patients were males. Most patients (80%) had lesions on the upper extremities. Fever and tenderness (60%) were the most commonly associated symptoms. Transient infections such as upper respiratory infection or gastroenteritis were the most common identifiable cause, observed in 40% of patients. Histopathologically, dermal neutrophilic infiltration was observed in all patients. All patients were treated with systemic corticosteroids and showed a good response, although 26.7% of the patients experienced symptom recurrence. During the follow-up period, there were no incidences of any complications or extracutaneous manifestations in the patients. Conclusion: In contrast to previous reports of pediatric Sweet syndrome, female predominance was observed in this study. Transient infection was the most common factor. All patients responded well to systemic corticosteroid therapy without complications or extracutaneous manifestations during the follow-up period. (Korean J Dermatol 2021;59(3):167∼174)