천연 Gum의 Rat 피부조직에서의 영향 연구

홍장후,김운겸 서울産業大學校 2002 논문집 Vol.53 No.1

Gum Films were prepared by solution blending in the weight ratio of natural gums(Xanthan, Locust bean and Guar) for the purpose of useful bio-implants. The possibility of bio-implants, which prepared from natural gums as a skin substitute was evaluated by measuring biodegradability. This biodegradable films were inserted in the back of rats and their of biodegradability were investigated by hematological change evaluation as a function of time to the bio-transformation. These values of biodegradable films, which prepared from natural gums measured in this study were some stable results at short period with those of ideal skin bio-implants.

Naphthoquinone diazide 유도체의 합성과 특성 연구

홍장후,김운겸 서울産業大學校 2002 논문집 Vol.53 No.1

Naphthoquinone diazide derivatives members of quinone diazide compound that are utilizable as photosensitive polymer material were synthesized, and photoresist were prepared by mixing these derivatives with a matrix resin at various weight ratios. Photosensitive characteristics of photoresist were studied by examining UV and IR, relative sensitivity using a Gray scale method, and SEM to analyze if they can be used as photosensitive material in printing process. Experimental results showed that, by UV, NQD derivatives were photo-converted and developer-soluble photoresist were produced. The mixing ratio of 1 : 4(by mass) of NQD+ ballast and m - cresol novolak gave rise to the highest dissolution rate. In addition, photoresist obtained at this condition resulted in the most superior sensitivity and contrast.

탈아미노반응과 니트로화 반응을 이용한 아닐린과 이소퀴놀린 유도체의 합성

홍장후,김운겸,최상회 서울産業大學校 1999 논문집 Vol.49 No.2

This study is to develop a new synthetic method for the nitroarenes vis non-electrophilic substitution. Direct nitration at the C-1 position of isoquinoline has never been reported and substitution in isoquionoline under the normal nitration condition occurs at C-5 and C-8. We have demonstrated a facile one-step sythetic method for the nitration of isoqunolines at the C-1 position, which involves the electrophilic attack of a DMSO-Ac₂O complex, followed by nucleophilic addition of nitrate ion the this intermeddiate. Since the reaction is simple and mild, this method has preparative merit since 1-nitroisoqunolines are nto readily accessible by other methods. Application to the synthesis of poly nitroarenes from the corresponding anilines was also described.

항고지단백혈증제의 천연고분자 기재에서의 피부투과 특성

홍장후,김운겸 서울産業大學校 2001 논문집 Vol.52 No.1

Transdermal delivery system(TDS) is often used as the method of drug dosage into the epidermic skin. Natural polymer were selected as ointment material of TDS. We investigated the permeation of natural polymer ointment containing drug in rat skin using horizontal membrane cell model. Permeation properties of materials were investigated for water-soluble drug such as oxiniacic acid in vitro. These results showed that skin permeation rate of drug across the composite was mainly dependent on the property of ointment base and drug. Proper selection of the polymeric materials which resemble and enhance properties of the delivering drug was found to be important in controlling the skin permeation rate. This result suggests a possible use of natural polymer ointment base as TDS of antihyperlipoproteinemic agent.

효율적인 휘발성 물질의 파괴에 관한 연구

홍장후,정택서,김운겸 서울産業大學校 1998 논문집 Vol.47 No.1

The Galnium have been load on the zeolit. and desorption the volatile organic compounds at ambient. and tested for their ability with catalytical destroy them at elevated temperature (ca. 350℃). these media, which act as both sorbent and catalysts, are believed to be the key to implementing a new energy efficient process for the destruction of low conentration level voc materials. Data show catalytic activity, sorptivity and other physical properties for Y and ZSM-5(Ga/ZSM-5) medium which showed superior performance catalytically > 92% toluene and xylene destruction at 300℃. The ambient adsortion capacity showed that toluene 12~14Wt%> and p-xylene 9.5~6.0Wt%. these tests showed that ambient temperature fixed bed sortion of voc followed by periodic heating of the upper portion to desorb trapped for their destruction. A Ga/ZSM-5 position which have been choice to 1500Pppm by user at a space velocity of 2500h¹, was showed to operate over a 1000min cycle which requied heating fo only 50%of the operating time.

Cu/ZSM-5촉매에 대한 NO 및 NH₃TPD 연구

홍장후,정택서,김운겸 서울産業大學校 1996 논문집 Vol.44 No.1

The effect of catalyst acidity and of its absorption property on the catalytic have examined for caption exchanged ZSM-5. Adsorption property of the NH₃and NO over HZSM-5 and Cu/ZSM-5 catalyst was investigated by NH₃,NO TPD. Also, room temperature adsorption and temperature-programmed desorption(TPD) of NO over a Cu/ZSM-5 catalyst active for NO decomposition were investigated. Even at 25℃ N₂O and N₂ were observed as reaction products during NO adsorption but they ceaced when NO adsorption was completed. During NO TPD N₂O , NO and O₂ desorptionpr peaks were observed. A oxygen desorption peak was detected at Ca360 ℃. No decompositive was detected without copper present. NO TPD was also collected over reduced and oxidized catalysts.

PS 판용 Naphthoquinone-(1,2)- diazide-5-sulfonic acid esters의 합성 및 응용

홍장후,정택서,김운겸 서울産業大學校 1999 논문집 Vol.50 No.2

본 연구는 Sodium-2-diazo-napthoquinone-5-sulfonate를 chlorination하여 2-diazo-naphthoquinone-5-sulfonylchloride(NQD-Cl)를 합성하였으며 합성된 NQD-Cl을 여러 종류의 hydroxybenzophenone 유도체와 esterification하여 hydroxy group이 2-diazo-napthoquinone-5-sulfonyl(NQD) group으로 치환된 여러 종류의 naphthoquinone-(1,2)-diazide-5-sulfonic acid esters(NQD-ester)를 합성하였다. NQD-ester의 용해도를 증가시키기 위해 methoxy group이 도입된 유도체와 이와 비교를 위해 hydroxy group만을 가지는 benzophenone 유도체를 사용하여 비교 검토하였다. 합성된 각각의 NQD-ester의 용해특성을 조사하였으며, novolac수지와 formulation하여 감광액을 제조하였다. 제조된 감광액을 알루미늄판에 도포, 건조하여 PS판을 제조하고 감광특성과 광퇴색도와 화상형성에 적합한 노광시간을 조사하였으며, 상대감도를 gray scale(GS)법으로 조사하였다. 치환된 NQD group의 수에 따라 GS법에 의한 상대감도가 다르게 나타나는 것을 알 수 있었다. Methoxy group이 도입된 NQD-ester는 좋은 용해특성을 보여주었으며 시판되는 PS판과 동일한 노광조건에서 비교해 본 결과 보다 우수한 감도를 보였다. 2-Diazo-l-naphthoquinone-5-sulfonyl chloride(NQD-Cl) was synthesized from Sodium-2-diazo-napthoquinone-5-sulfonate by chlorination. Synthesized NQD-Cl was esterified with hydroxybenzophenones to give several naphthoquinone-(1,2)-diazide-5-sulfonic acid esters(NQD-esters). We are investigated comparing benzophenone derivatives with methoxy group and benzophenone derivatives with hydroxy group. Solubility of each NQD-esters was studied and each of NQD-esters was formulated w novolac base resin and PS plates were manufactured. Photosensitivity, bleachability, compatible exposed time and relative sensitivity were determined by UV spectro photometry, imaged by UV lithographic techniques and grey scale method. According to the number of substituted NQD group, it showed that relative sensitivity was different from grey scale. NQD-esters with methoxy group were shown a good solubility and higher sensitivity than commercial PS ones.

ZSM-5 촉매를 이용한 메탄올의 탄화수소화 반응

홍장후,정택서,김운겸 서울産業大學校 1996 논문집 Vol.44 No.1

ZSM-5 catalysts were prepared from Na₂SiO₂-Al₂O₃-TPAOH-H₂O system by hydrothermal process. Catalysts showed characteristics of ZSM-5 crystal structure and composwd of various size of small twin crystals which were confirmed by X-RD and SEM analysis respectively. Methanol conversion reactions were performed by changing the reaction time, temperature, space velocity and partial pressure of the reaction system. selectivity of catalist with reaction time reaction time was increased a products of the paraffine. Temperatures was large effective than the other parameters. Space time were changed from 0.06 to 2.64[g cat-hr/g mole]highest at 1.98. Deactivated catalysts were regenerated by passing the air from 2 hours at 500℃. As the number of regeneration increased selectivity to low grade olefine.

알긴 첨가형 고분자 블랜드의 특성과 Pot Test

홍장후,신현진,김운겸,강경묵 서울産業大學校 1999 논문집 Vol.49 No.2

PVA/Algin blend films were prepared by solution blending method for the purpose of useful biodegradable polymer. Characteristics properties of blend films such as DSC, Elongation, Tensile strength and Morphological changes by SEM were determined. Tensile strength and Elongation were rapidly reduced as increasing the blend ratio of Algin. Blend films were found that phase separation was occured as more than 25wt% increasing the blend ratio of Algin. Blend films were observed to be less partially compatibility than 10wt% increasing the blend ratio of Algin by DSC, mechanical properties and SEM Also, Blend films at the laboratory soil test(Pot Test) were completely degraded in months with four kinds of soils by microganisms.

ZSM-5제올라이트 합성에 관한 연구

홍장후,정택서,강경묵,김운겸 서울産業大學校 1998 논문집 Vol.47 No.1

A pentasil zeolite. ZSM-5 was succesfully synthesized at low temperature and atmospheric pressure. The experinments were carried out in four different methods 1, 2 and 3 depending on the concentrations of water, organic template. TPABr (tetrapropy-lammonium bromide) and the presence or absence of seed, the overall molar composition used in this study was 7.83 Na₂O-0.25 Al₂O₃-100SiO₂-xTPABr-yH₂o where x is 1 and 3 mol, and y is 3000mol, 3500mol, and 4000mol. 2³factorial experiments were performed with the results of kinetics studies Na₂O, TPABr and H₂O as main factors, The result showed that the concentration of H₂O is the most important.