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反芻動物의 肝蛭類 및 胃腸內線蟲類에 對한 Nitroxynil-Levamisole 複合注射劑 詩製品의 驅蟲效果評價試驗
田桂植,閔弘基,張斗煥 梨花女子大學校 醫科大學 醫科學硏究所 1990 EMJ (Ewha medical journal) Vol.13 No.3
The present study was carried out to evaluate the efficacy of the experimentally prepared injection of nitroxynil-levamisole against liver fluke and gastrointestinal roundworms in goats and cattle. For the purpose, the dose confirmation trial, the dose reduction trial and clinical field trial were conducted according to "the guidelines for evaluating the efficacy of anthelmintics in ruminants" approved by the General Meeting of the 9th International Conference of the World Association for the Advancement of Veterin ary Parasitology" in 1981. The results obtained are summarized as follows ; 1) A single dose of 10mg/kg of nitroxynil injection alone against the liver fluke and that of 5.0mg/kg of levamisole injection alone against gastrointestinal roundworms in goats were highly effective in the cure rate and the egg reduction rate, respectively. 2) A single dose of the experimentally prepared compound injection at the dose levels of nitroxynil 10.0mg-12.0mg/kg and levamisole 5.0mg-6.0mg/kg was highly effective in the egg reduction rates of both liver fluke(98.4%-100%) and gastrointestinal roundworms(97.3%-98.4%) without any side reaction in goats. 3) A single does of the experimentally prepared compound injection at the reduced dose level of nitroxynil 7.5mg/kg and levamisole 5.0mg/kg was highly effective in the egg reduction rates of both liver fluke and gastrointestinal roundworms in goats. 4) In the clinical field trial, a single dose of the experimentally prepared compound injection at the reduced dose level of nitroxynil 7.5mg/kg and levamisole 5.0mg/kg showed also very high efficacy in the cure rates and the egg reduction rates of both liver fluke and gastrointestinal roundworms in Korean cattle, dairy cow and beef cattle. However, it was not effective against Ostertagia sp. among gastrointestinal roundworms. No side reactions were noted.
돼지 내부기생충(內部寄生蟲)의 현황(現況)과 돼지 배분(排糞)의 검사성적(檢査成績)
장두환,Jang, Du Hwan 대한수의학회 1975 大韓獸醫學會誌 Vol.15 No.2
In survey for internal parasites of 395 heads of swine by fecal examination at ict, incidences of each parasite were obtained as follows: Giardia lamblia 1.0% Entamoehaspp. 55.4 Eimeria& Isospora spp. 22.5 Balantidium coli 66.6 Metastrongylus elongatus 17.6 Ascaris suum 25.6 Oesophagostomun dentatum 29.1 Hyostrongylus ryubidus 14.6 Trichuris suis 4.2 Strongyloides ransomi 7.2 Mecistocirrus digitatus 1.0 Check-list for the internal parasites of swine made by all the materials repor years from 1920 to 1975 in Korea is as follows: No. Parasites Habitat References 1. Ascaris lumbricoides small intestine Kawamura(1923) 2. Oesophagostomum dentatum large intestine Kawamura(1923) 3. Echinococcus veterinorum lung & liver Kawamura(1923) 4. Cysticercus cellulosae muscle Yunoba(1923) 5. Sarcooystis sp. muscle Arahayase(1927) 6. Entamoeba polecki intestine Kuwabara(1931) 7. Balantidium coli large intestine Huruyama(1931) 8. Metastrongylus elongatus lung Lee(1956) 9. Gongylonema pulckrum oesophagus Isshiki(1960) 10. Ascarops strongylina stomach Isshiki(1960) 11. Cysticercus tenuicollis peritoneum Isshiki(1960) 12. Cysticercus bovis? diaphragm Isshiki(1960) 13. Toxoplasma gondii interna organs Mun(1960) 14. Trichuris suis large intestine Lee et al.(1963) 15. Stephamirus dentatus feces Lee et al.(1963) 16. Spirometra mansonides fat layer of muscle Jang(1964) 17. Hyostrongylus rubidus stomach Kim et al.(1969) 18. Strongyloides ransomi feces Kim et al.(1969) 19. Eimeria perminuta feces Jang(1972) 20. E. debrieki feces Jang(1972) 21. E. polita feces Jang(1972) 22. E. scabra feces Jang(1972) 23. E. scrofae feces Jang(1972) 24. Isospora suis feces Jang(1972) 25. Entamoeba coli feces Jang(1975) 26. Mecistocirrus digitatus feces Jang(1975) 27. Giardia lamblia feces Jang(1975).
Du Hwan JANG(張斗煥),Yung Bai KANG(姜英培) 한국예방수의학회 1989 예방수의학회지 Vol.13 No.1
A nation-wide survey on Cysticercus celluosae infections in swine was carried out and the results obtained were summarized as follows. 1. Among 355 farms in 9 regions investigaed, the half(176 farms, 49.6%) was noticed as the conventional farming style not fully modernized pigeries and 53 farms(14.9%) were identified as under-developed farming style still using the human feces for pig feeding. 2. In the biopsy on a total of 36,640 pigs, 5 pigs rearing in Cheju Island were readily identified as positive with C. cellulosae infection. 3. Among 3,799 slaughting pigs in 54 abattoirs in 9 regions in Korea, a total of 12 pigs(0.32%) was diagnosed as C. cellulosae infected, and the positive cases were recognized with the regional significances, such as, Cheju 1.7%, Kyungnam 0.61% and Chonnam 0.32%.
囊尾蟲 自然感染 및 人工感染 돼지에 對한 藥劑 治療試驗
Du Hwan JANG(張斗煥),Yung Bai KANG(姜英培),Sung Ho KIM(金承鎬),Ki Sun OHM(嚴基善) 한국예방수의학회 1989 예방수의학회지 Vol.13 No.1
For the treatment of Cysticercus cellulosae infectons in swine both naturally or artificially infected, the candidate anthelmintics flubendazole, oxybendazole and praziquantel were tested and the results obtained were summmarized as follow. 1. In the naturally infected pigs the anthelmintics presented resonably high anthelmintic activities such as flubendazole 80.2%, oxybendazole 79.7% and praziquantel 61.6%. 2. In the artificially infected piglets with Taenia solium eggs isolated from human feces, the anthelmintics presented relatively good anthelmintic activities, however, there were no signficant differences among the efficacy of the drugs tested.
EFFECTS OF TEMPERATURE ON VIABILITY OF SARCOCYSTS OF Sarcocystis cruzi IN CARDIAC MUSCLE OF CATTLE
노재운(Jae Woog NOH),장두환(Du Hwan JANG),강영배(Yung Bai KANG),장환(Hwan JANG),위성환(Sung Hwan WEE) 한국예방수의학회 1988 예방수의학회지 Vol.12 No.2
돼지의 Sarcocystis miescheriana와 소의 S. cruzi는 사람을 종숙주로 할 수 있으며 이들은 사람이나 동물이 감염력을 가진 cyst를 함유한 고기를 날것이나 덜 조리된 상태로 먹을 때 감염이 일어난다. 그러므로 Sarcocystis의 전파를 막는 한 방법으로써 식육내에 감염력이 있는 cyst를 파괴하는 것이다. 본 연구는 식육내에 있는 Sarcocystis의 감염력이나 생존력이 식육의 처리온도와 시간에 따라 어떻게 변화하는가를 조사하였으며 생존력은 0.5% trypsin 소화법에 의해 검출되는 bradyzoites의 유무로 판단하였다. 소의 심근을 -20℃와 -10℃에 90분 그리고 -5℃에 17시간 보존시 감염력이 상실되었으나 0~4℃에서는 11일간 보존시에도 감염력을 가진 것으로 나타났다. 40℃에서 17시간동안 처리된 심근내의 Sarcocystis는 파괴되었으며 60℃, 100℃에서는 5분과 2분의 짧은 처리시간에서 감염력이 상실되었다.