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RISS 인기검색어
- 검색키워드
- 저자 : Jamshid Soltani-Nabipour (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
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Evaluation of dose distribution from 12C ion in radiation therapy by FLUKA code
Jamshid Soltani-Nabipour,Abdollah Khorshidi,Faezeh Shojai,Khazar Khorami 한국원자력학회 2020 Nuclear Engineering and Technology Vol.52 No.10
Heavy ions have a high potential for destroying deep tumors that carry the highest dose at the peak of Bragg. The peak caused by a single-energy carbon beam is too narrow, which requires special measures for improvement. Here, carbon-12 (12C) ion with different energies has been used as a source for calculating the dose distribution in the water phantom, soft tissue and bone by the code of Monte Carlo-based FLUKA code. By increasing the energy of the initial beam, the amount of absorbed dose at Bragg peak in all three targets decreased, but the trend for this reduction was less severe in bone. While the maximum absorbed dose per bone-mass unit in energy of 200 MeV/u was about 30% less than the maximum absorbed dose per unit mass of water or soft tissue, it was merely 2.4% less than soft tissue in 400 MeV/u. The simulation result showed a good agreement with experimental data at GSI Darmstadt facility of biophysics group by 0.15 cm average accuracy in Bragg peak positioning. From 200 to 400 MeV/u incident energy, the Bragg peak location increased about 18 cm in soft tissue. Correspondingly, the bone and soft tissue revealed a reduction dose ratio by 2.9 and 1.9. Induced neutrons did not contribute more than 1.8% to the total energy deposited in the water phantom. Also during 12C ion bombardment, secondary fragments showed 76% and 24% of primary 200 and 400 MeV/u, respectively, were present at the Bragg-peak position. The combined treatment of carbon ions with neutron or electron beams may be more effective in local dose delivery and also treating malignant tumors.
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Lung tumor segmentation using improved region growing algorithm
Jamshid Soltani-Nabipour,Abdollah Khorshidi,Behrooz Noorian 한국원자력학회 2020 Nuclear Engineering and Technology Vol.52 No.10
The goal of this project is to achieve an accurate segmentation of the pulmonary tumors besides shortening the time and increasing the accuracy. Here, improved region growing (IRG) algorithm is introduced in order to segment the lung tumor with a sufficient accuracy in a shorter time compared to the other basics methods. This comprehensive algorithm was applied on 4 patients CT images and the results of the various steps on segmentation improvement shown 98% accuracy as compared to the basic algorithm. The combination of “multipoint growth start” produced a desirable outcome in accurately bounding the tumor. The proposed algorithm improved tumor identification by less than 13% along with a sufficient percentage of compliance accuracy.
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Simulation and assessment of 99mTc absorbed dose into internal organs from cardiac perfusion scan
Salari Saghar,Khorshidi Abdollah,Soltani-Nabipour Jamshid 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.1
Directly, it is not possible to measure the absorbed dose of radiopharmaceuticals in the organs of the human body. Therefore, simulation methods are utilized to estimate the dose in distinct organs. In this study, individual organs were separately considered as the source organ or target organ to calculate the mean absorption dose, which SAF and S factors were then calculated according to the target uptake via MIRD method. Here, 99mTc activity distribution within the target was analyzed using the definition and simulation of ideal organs by summing the fraction of cumulative activities of the heart as source organ. Thus, GATE code was utilized to simulate the Zubal humanoid phantom. To validate the outcomes in comparison to the similar results reported, the accumulation of activity in the main organs of the body was calculated at the moment of injection and cardiac rest condition after 60 min of injection. The results showed the highest dose absorbed into pancreas was about 21%, then gallbladder 18%, kidney 16%, spleen 15%, heart 8%, liver 8%, thyroid 7%, lungs 5% and brain 2%, respectively, after 1 h of injection. This distinct simulation model may also be used for different periods after injection and modifying the prescribed dose
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