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RISS 인기검색어
- 검색키워드
- 저자 : James R. Lawrence (검색결과 3 건)
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Kiseong Hyeong,James R. Lawrence 한국지질과학협의회 2003 Geosciences Journal Vol.7 No.1
A hydrological study using oxygen isotopic ratiosand salinities was carried out in the San Bernard-Brazos RiverEstuaries, Brazoria County, Texas, USA, to understand the influ-ence of 4 fresh water sources draining into the area, Brazos River,San Bernard River, Oyster Creek, and Jones Creek, on variousparts of the Gulf Intra-Coastal Waterway (GIW) that transectsthese rivers half to 1 mile inland of the Gulf of Mexico. The mea-sured oxygen isotopic ratios and salinities of GIW waters areexplained with simple mixing between one of the 4 fresh watersources with marine water and made it possible to identify 3 sub-areas of the GIW, each of which is influenced by different fresh-water source. These sub-areas locate on the western part of theBrazos River, between the Brazos and Old Brazos River, and onthe eastern part of the Old Brazos River, and have their freshwa-ter source from the San Bernard River, Brazos River, and OysterCreek, respectively. An interesting result was found in the GIWbetwen the San Bernard and Brazos Rivers, where fresh water ismainly sourced from the San Bernard River although its dis-charge rate is 40 to 100 times less than that of the Brazos River.This westerly flow of the San Bernard River toward the largerBrazos River is due to shallowing of the San Bernard River at theriver mouth, which restricts free discharge of river water to opensea and diverts the flow toward the GIW on both sides of the river.The influence of the other two creeks, Oyster and Jones, wasminor and limited near the confluence with the GIW due to minorinfluxes. The generalized flow pattern derived in this study isessential for the construction of contingency plan against toxiccontaminations, which wil minimize environmental impact onnumerous organisms living in the GIW. The results of this studyare also useful for tracing of contaminants in the studied GIW.
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Concentrations of Cyclosporin A and Metabolites in the Gingival Tissues of Transplant Patients
Camargo, Paulo M.,Wolinsky, Lawrence E.,McBride, James H.,Barrie Kenney, E.,Carranza, Fermin A.,Klokkevold, Perry R.,Robert Ettinger,Jennifer Marik Korean Academy of Oral Biology and the UCLA Dental 1999 International Journal of Oral Biology Vol.24 No.4
Cyclosporin A (CyA) is a potent immunosuppressive drug used to avert rejection following human organ transplant surgery and as therapy for various atuoimmune diseases. One complication associated with CyA therapy is gingival enlargement observed post transplantation. The purpose of this study was to determine if concentrations of CyA and its metabolites in the gingival tissues of patients presenting with gingival enlargement (responders) were higher than those in patients without enlargement (nonresponders). Ten organ transplant recipients (9 kidney, 1 liver) woh were receiving CyA for at least 6 months were classified clinically as responders and nonresponders. Site selection for biopsy was based on the degree of gingival enlargement and all biopsy sites presented minimal plaque and gingival inflammation. One biopsy was taken from each of the nonresponders and two were taken from the responders (one enlarged and one nonenlarged area). CyA concentrations in the biopsies were determined by HPLC and CyA plus metabolites was determined by Abbott TDx. Mean results demonstrated that enlarged and nonenlarged sites in responders presented with similar concentrations of CyA and CyA plus metabolites No statistically significantdifferences were found between the concentration of cya or cya plus metabolites in nonenlarged sites of responders when compared to nonenlarged sites of nonresponders, although nonresponders demonstrated higher values. Finally, enlarged sites in responders showed lower but not statistically significant concentrations of CyA or CyA plus metabolites than nonenlarged sites in nonresponders. This study demonstrates that the concentration of CyA and CyA plus metabolites in the gingival tissues of individuals taking the drug is not the single determinant factor in the development of gingival enargement.
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EFFECT OF EXTERNAL ELECTRICAL STIMULI ON DNA-BASED BIOPOLYMERS
GURU SUBRAMANYAM,CARRIE M. BARTSCH,JAMES G. GROTE,RAJESH R. NAIK,LAWRENCE L. BROTT,MORLEY STONE,ANGELA CAMPBELL 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2009 NANO Vol.4 No.2
Biopolymers, such as deoxyribonucleic acid-hexadecyltrimethyl ammonium chloride (DNA-CTMA) and bovine serum albumin-polyvinyl alcohol (BSA-PVA), were studied using a novel capacitive test structure. A variety of external electrical stimuli were applied, including a low frequency alternating current signal and a rf/microwave frequency signal combined with a DC bias. The dynamic responses of the DNA-based biopolymer to the external stimuli are presented in this paper. The electrical transport measurements support the space-charge-limited conduction and the low frequency capacitance–voltage (CV) measurements showed large depletion layer capacitance at the Au–biopolymer interface, at 20 Hz, and the capacitance approaching bulk values at 1 MHz. Electric force microscopy (EFM) was utilized for visualization of charge dynamics and to examine the effect of DC bias combined with an AC signal. Ionic charges in the DNA-CTMA system seem to be responsible for the dynamic response to the various external electrical stimuli.
RISS
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