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변환된 중국어를 복사하여 사용하시면 됩니다.
오재승(Jaeseung Oh),김황수(Hwangsoo Kim) 한국정보과학회 2000 정보과학회논문지 : 소프트웨어 및 응용 Vol.27 No.12
본 논문에서는 유전자 알고리즘과 피라미드(다단계 또는 다 해상도)를 결합한 새로운 영상 분할 방법을 제안한다. 먼저, 영상을 피라미드의 해상도가 낮은 상위 단계로 분할하고 좋은 적합도를 가진 염색체의 개체군을 얻는다. 둘째, 해상도를 높인 다음 단계의 입력으로 앞 단계에서 얻은 염색체들을 사용하며, 더욱 세분화된 분할이 이루어지도록 염색체를 진화시킨다. 유전자 알고리즘의 적합함수는 각 영역의 균질성과 peakiness를 이용하여 정의하였다. 교차는 교차점을 중심으로 영상을 2분하여 서로 교환하는 1 점 교환법을 사용하였으며, 돌연변이는 병합과 분할이 이루어지도록 설계하였다. 본 논문은 저 해상도에서 가능성(적합성)이 큰 유전자를 신속히 구한 후에 단계적으로 고 해상도에서 적합한 유전자로 진화시켜 나가는 방법으로 처음부터 최고 해상도에 유전자 알고리즘을 적용하는 종전의 방법보다 훨씬 더 효율적이며 유전자 알고리즘과 다단계 기법의 이상적인 결합이라 할 수 있다. 분할 결과에서도 타 알고리즘에 비하여 우수하거나 비슷한 결과를 얻었다. In this paper, a novel image segmentation technique which combines the genetic algorithm and pyramid (multi-resolution) approach is presented. First, we segment an image at coarse ( high ) level of pyramid, and retain a population of chromosomes which have good fitness values. Second, we use these chromosomes as the input of the next level that has higher resolution, and they evolve to represent more detailed segmentation. The fitness function of the genetic algorithm is defined using uniformity and peakiness of each region. The cross-over process uses 1-point crossover which exchanges parts of two images each of which is divided into two parts. The mutation process takes merge and split process into account. Using low-resolution image at first, This method obtains chromosomes which have high fitness values. fast, then they are evolved into chromosomes with high fitness values for higher resolution image. Compared to conventional genetic segmentation, this method is much more effective. It is a clever combination of genetic algorithm and pyramid approach. Experiments show comparable or better results compared to other methods.
Oh, MinKyung,Yoon, Jaeseung,Cho, Doo-Yeoun Adis International 2015 Clinical drug investigation Vol.35 No.10
<P>A new biosimilar human recombinant epoetin alfa product (PDA10) has been developed by PanGen Biotech Inc., Korea. This study was planned to demonstrate the pharmacokinetic and pharmacodynamic comparability of PDA10 to an existing epoetin alfa (Eprex) after a single intravenous administration to healthy adult male volunteers.</P>
Auditory imagery modulates frequency-specific areas in the human auditory cortex.
Oh, Jihoon,Kwon, Jae Hyung,Yang, Po Song,Jeong, Jaeseung Published by the MIT Press with the Cognitive Neur 2013 Journal of cognitive neuroscience Vol.25 No.2
<P>Neural responses in early sensory areas are influenced by top-down processing. In the visual system, early visual areas have been shown to actively participate in top-down processing based on their topographical properties. Although it has been suggested that the auditory cortex is involved in top-down control, functional evidence of topographic modulation is still lacking. Here, we show that mental auditory imagery for familiar melodies induces significant activation in the frequency-responsive areas of the primary auditory cortex (PAC). This activation is related to the characteristics of the imagery: when subjects were asked to imagine high-frequency melodies, we observed increased activation in the high- versus low-frequency response area; when the subjects were asked to imagine low-frequency melodies, the opposite was observed. Furthermore, we found that A1 is more closely related to the observed frequency-related modulation than R in tonotopic subfields of the PAC. Our findings suggest that top-down processing in the auditory cortex relies on a mechanism similar to that used in the perception of external auditory stimuli, which is comparable to early visual systems.</P>
초파리 TFIIB, TBP 유전자들의 Promoter 부위 비교 및 발현
이광수,오윤상,최강률,백광희,윤재승 경희대학교 유전공학연구소 1995 遺傳工學論文集 Vol.7 No.-
Our main interest is the regulation of expression of the genes for general transcription factors involved in the transcription process by RNA polymerase Ⅱ. For this purpose, we have been trying to isolate and characterize the genomic clones encoding various transcription factors of Drosophila melanogaster. In this paper, we report the DNA sequences of the promoter regions of Drosophila TFIIB and TBP genes and suggest some consensus features in those regions We also present the developmental profile of mRNA expression of those two Drosophila genes. The data altogather suggest some common mechanism existing in the regulation of the expression of these two Drosophila genes.
오동현(DongHyeon Oh),최재승(JaeSeung Choi),차상길(SangKil Cha) 한국정보보호학회 2020 정보보호학회논문지 Vol.30 No.4
퍼징은 입력값을 무작위로 생성해 소프트웨어를 테스팅하는 방법으로, 처음 고안된 이래로 다양한 방식의 퍼징이 연구되고 있다. 그중 변이기법을 적용한 퍼징은 확률에 따른 비트 반전이나 특별 값 치환과 같이 비교적 간단한 접근법을 사용함에도, 많은 버그를 발견해온 만큼 효율적인 방법이라고 할 수 있다. 하지만 인터프리터는 문법, 시맨틱이 올바른 입력값을 요구하기 때문에 일반적인 변이기법을 적용하기에는 어려움이 있다. 이에 본 연구에서는 동적 데이터 흐름 분석을 통해 변이기법을 인터프리터 퍼징에 적용할 수 있는 방법에 대해 제시하고자 한다. 본 연구에서 제시하는 JMFuzzer는 문법, 시맨틱의 올바름을 고려해 자바스크립트 인터프리터에서 오류 없이 정상적으로 동작하는 다양한 유형의 테스트케이스를 생성할 수 있다. 최종적으로 본 연구에서는 최신 버전의 자바스크립트 인터프리터에서 알려지지 않은 취약점들을 찾았으며, 이를 각 회사에 제보했다. Fuzzing is a method of testing software by randomly generating test cases. Since its introduction, a variety of fuzzing techniques have been studied. Among them, mutation-based fuzzing is an efficient method that finds real-world bugs even though it uses a simple approach such as probabilistic bit-flipping and character substitution. However, the interpreter fuzzing has difficulty in applying general mutation techniques because the interpreter requires grammar and semantic correctness input values. In this paper, we present a novel mutation-based fuzzing on JavaScript interpreters with a dynamic data flow analysis. To this end, we implement JMFuzzer that can generate various types of mutated test cases that operate normally without runtime errors in JavaScript interpreter considering syntax and semantics. As a result, we found numerous unknown vulnerabilities in the latest JavaScript interpreters. We reported all of them to the vendors.
Analysis of the Structure and Expressionof the TFIIB Gene in Drosophila melanogaster
Lee, Kwang-Soo,Oh, Younsang,Baek, Gumhee,Yoon, Jaeseung,Han, Kyuhyung,Cho, Namyoung,Baek, Kwanghee 대전대학교 이과대학 기초과학연구소 1997 自然科學 Vol.- No.-
We have isolated and characterized a genomic clone encoding the Drosophila melanogaster transcription factor IIB (TFIiB). The coding region of the TFIIB gene is interrupted by three short introns. The 5 -flanking region of the gene lacks the typical TATA box sequence like those of other known genes encoding the general transcription factors. In addition, the 5 -flanking region of the gene contains several common DNA sequences present in Drosophila TBP and THIS genes, suggesting the common regulation mechanism of gene expression. RNA blot analysis revealed that the gene expresses 1.6 kb, 1.3 kb and 1.2 kb mRNAs throughout development and in adults. Deletion analysis of the promoter region shows that the minimal promoter necessary for efficient expression is located between -698 (Psti) and f 6 0 relative to the transcription start point. Within this minimal promoter region, the upstream regulatory element responsible for the stimulation of gene expression may exist in the DNA fragment between - 698 (PstI) and - 351 (StuI).