The prediction of the tooth size in the mixed dentition for Korean

Moon, Sung-Hwan,Kim, Seong-Oh,Yu, Hyung-Seong,Choi, Byung-Jai,Choi, Hyung-Jun,Lee, Jae-Ho 大韓小兒齒科學會 2006 大韓小兒齒科學會誌 Vol.33 No.2

이번 연구의 목적은 혼합치열기 아동에서 미맹출된 견치와 소구치의 크기를 예측하는데 있어서 한국인에 맞는 방정식을 만들기 위함이다. 미맹출 치아의 크기를 예측하는 것은 혼합치열기 교정 진단과 치료계획 수립에 있어서 매우 중요하다. 미맹출된 견치와 소구치 크기를 예측하는 방법은 몇가지가 있지만 그중에서도 가장 흔하게 쓰이는 것이 모이어의 예측표와 다나카와 존스턴의 방정식이 있다. 하지만 그것들은 백인을 위해서 제작된 것이고 치아 크기는 인종에 따라서 다르다고 알려져 있다. 이번 연구에서는 치아크기를 측정하여 하악 영구 절치의 크기 합과 견치 및 소구치의 크기 합 사이의 상관관계를 구하고 회귀방정식을 이용해서 한국인에 맞는 예측표를 만들었다. 연세대학교 치과대학에 재학중인 178명의 한국 학생(남 108명, 여 70명, 평균연령 21.63)을 대상으로 실험하였다. 영구치의 근원심 폭경을 석고모형상에서 calipers를 이용해서 측정하였다. 성별간의 치아 크기는 차이가 있었다(p<0.05). Correlation coefficient는 0.57에서 0.64의 범위였고, standard errors of the estimates 는 여성에서 0.6으로써 남성보다 우수하였다. r^(2)값은 0.27에서 0.41의 범위를 나타내었다. Estimating the size of unerupted teeth is an essential aspect of orthodontic diagnosis and treatment planning in the mixed dentition. Several methods were introduced and used for the prediction. The most common methods among these would be Moyers probability chart and Tanaka and Johnston equations. These are currently used widely, but they were developed for Caucasians. Because there are clear racial differences in teeth size, the objectives of this study were to produce correlation coefficients between the combined mesiodistal widths of the permanent mandibular incisors and those of the canines and premolars for each quadrant, and prediction tables with regression equations, specifically for Korean. 178 young adults (70 women, 108 men, mean age 21.63 years) were selected from the College of Dentistry, Yonsei University, Seoul, Korea. The mesiodistal crown diameters of the permanent teeth were measured with calipers. Significant sexual dimorphism was found in tooth sizes. The correlation coefficients between the total mesiodistal width of the mandibular permanent incisors and those of the maxillary and mandibular canines and premolars were found to be between 0.52 and 0.64. The standard error of the estimatation was better (0.60) for women and the r^(2) values ranged from 0.27 to 0.41 for both sexes, Prediction tables were prepared for Korean. This study showed larger canine and premolar diameters than Tanaka and Johnston's and Moyers' studies which might be due to the racial differences. Further investigations with a larger sample size will be needed for more representative data on the Korean population.

A field study of colloid transport in surface and subsurface flows

Zhang, Wei,Tang, Xiang-Yu,Xian, Qing-Song,Weisbrod, Noam,Yang, Jae E.,Wang, Hong-Lan Elsevier, etc 2016 Journal of hydrology Vol.542 No.-

<P><B>Abstract</B></P> <P>Colloids have been recognized to enhance the migration of strongly-sorbing contaminants. However, few field investigations have examined combined colloid transport via surface runoff and subsurface flows. In a headwater catchment of the upper Yangtze River, a 6m (L) by 4m (W) sloping (6°) farmland plot was built by cement walls to form no-flow side boundaries. The plot was monitored in the summer of 2014 for the release and transport of natural colloids via surface runoff and subsurface flows (i.e., the interflow from the soil-mudrock interface and fracture flow from the mudrock-sandstone interface) in response to rain events. The water sources of the subsurface flows were apportioned to individual rain events using a two end-member model (i.e., mobile pre-event soil water extracted by a suction-cup sampler <I>vs</I>. rainwater (event water)) based on <I>δ</I> <SUP>18</SUP>O measurements. For rain events with high preceding soil moisture, mobile pre-event soil water was the main contributor (generally >60%) to the fracture flow. The colloid concentration in the surface runoff was 1–2 orders of magnitude higher than that in the subsurface flows. The lowest colloid concentration was found in the subsurface interflow, which was probably the result of pore-scale colloid straining mechanisms. The rainfall intensity and its temporal variation govern the dynamics of the colloid concentrations in both surface runoff and subsurface flows. The duration of the antecedent dry period affected not only the relative contributions of the rainwater and the mobile pre-event soil water to the subsurface flows but also the peak colloid concentration, particularly in the fracture flow. The <10μm fine colloid size fraction accounted for more than 80% of the total suspended particles in the surface runoff, while the colloid size distributions of both the interflow and the fracture flow shifted towards larger diameters. These results highlight the need to avoid the application of strongly-sorbing agrochemicals (e.g., pesticides, phosphorus fertilizers) immediately before rainfall following a long no-rain period because their transport in association with colloids may occur rapidly over long distances via both surface runoff and subsurface flows with rainfall.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Subsurface flow was apportioned into rainwater and mobile pre-event soil water. </LI> <LI> The duration of no-rain period affects peak colloid concentration. </LI> <LI> Rainfall intensity and its temporal variation govern colloid discharge dynamics. </LI> </UL> </P>

Outcomes of Rate-Control Treatment in Patients With Atrial Fibrillation and Heart Failure — A Nationwide Cohort Study —

Yu, Hee Tae,Yang, Pil-Sung,Lee, Hancheol,You, Seng Chan,Kim, Tae-Hoon,Uhm, Jae-Sun,Kim, Jong-Youn,Pak, Hui-Nam,Lee, Moon-Hyoung,652, Boyoung Joung UNKNOWN 2018 CIRCULATION JOURNAL Vol.82 No.3

<P>Conclusions: Use of beta-blockers was associated with a reduced mortality rate for AF patient with HF but not for those without HF. These findings should be examined in a large randomized trial.</P>

Morphology-Driven High-Performance Polymer Transistor-based Ammonia Gas Sensor

Yu, Seong Hoon,Cho, Jangwhan,Sim, Kyu Min,Ha, Jae Un,Chung, Dae Sung American Chemical Society 2016 ACS APPLIED MATERIALS & INTERFACES Vol.8 No.10

<P>Developing high-performance gas sensors based on polymer field-effect transistors (PFETs) requires enhancing gas-capture abilities of polymer semiconductors without compromising their high charge carrier mobility. In this work, cohesive energies of polymer semiconductors were tuned by strategically inserting buffer layers, which resulted in dramatically different semiconductor surface morphologies. Elucidating morphological and structural properties of polymer semiconductor films in conjunction with FET studies revealed that surface morphologies containing large two-dimensional crystalline domains were optimal for achieving high surface areas and creating percolation pathways for charge carriers. Ammonia molecules with electron lone pairs adsorbed on the surface of conjugated semiconductors can serve as efficient trapping centers, which negatively shift transfer curves for p-type PFETs. Therefore, morphology optimization of polymer semiconductors enhances their gas sensing abilities toward ammonia, leading to a facile method of manufacturing high-performance gas sensors.</P>

Input sequencing and scheduling for a reconfigurable manufacturing system with a limited number of fixtures

Yu, Jae-Min,Doh, Hyoung-Ho,Kim, Ji-Su,Kwon, Yong-Ju,Lee, Dong-Ho,Nam, Sung-Ho Springer-Verlag 2013 INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TE Vol.67 No.1

Original Articles : Exophytic combined hepatocellular carcinoma and cholangiocarcinoma

( Sang Jae Noh ),( Hyun Kyung Lee ),( Hee Chul Yu ),( Woo Sung Moon ) 대한간학회 2012 Clinical and Molecular Hepatology(대한간학회지) Vol.18 No.4

New phenalenone derivatives from the Hawaiian volcanic soil-associated fungus Penicillium herquei FT729 and their inhibitory effects on indoleamine 2,3-dioxygenase 1 (IDO1)

Jae Sik Yu,Se Yun Jeong,Chunshun Li,Taehoon Oh,Mincheol Kwon,Jong Seog Ahn,Sung-Kyun Ko,Yoon-Joo Ko,Shugeng Cao,Ki Hyun Kim 대한약학회 2022 Archives of Pharmacal Research Vol.45 No.2

Phenalenone derivatives sourced from fungi arepolyketides that have attracted signifi cant interest becauseof their diverse chemical structures and potential bioactivities. As part of our ongoing quest to discover novel naturalproducts with biological properties from diverse naturalresources, three unreported phenalenone derivatives ( 1–3 ),named ent -12-methoxyisoherqueinone ( 1 ), (−)-scleroamide( 2 ), and (+)-scleroamide ( 3 ), together with four known phenalenonederivatives, ent -atrovenetinone ( 4 ), isoherqueinone( 5 ), herqueinone ( 6 ), and ent -peniciherquinone ( 7 ) wereisolated from the Hawaiian soil fungus Penicillium herqueiFT729, collected on the Big Island, Hawaii. Compounds 2 and 3 were enantiomers, which were separated using achiral-phase HPLC column, which provided optically purecompounds 2 and 3 . The structures of the novel compoundswere established by extensive spectroscopic analyses,including 1D and 2D NMR and high-resolution ESIMS. Their absolute confi gurations were determined using quantumchemical electronic circular dichroism (ECD) calculations. The inhibitory activity of the isolated compounds( 1–7 ) against indoleamine 2,3-dioxygenase 1 (IDO1) wasassessed. Compounds 1, 5–7 inhibited IDO1, with IC 50values of 32.59, 36.86, 19.05, and 24.18 μM, respectively. These fi ndings demonstrated that the phenalenone derivatives1 and 5–7, as IDO1 inhibitors, are promising anticancerimmunotherapeutic agents.

Effects of lamellar structure on tensile properties and resistance to hydrogen embrittlement of pearlitic steel

Yu, Sang-Hyun,Lee, Sang-Min,Lee, Sukjin,Nam, Jae-Hoon,Lee, Jae-Seung,Bae, Chul-Min,Lee, Young-Kook Elsevier 2019 ACTA MATERIALIA Vol.172 No.-

<P><B>Abstract</B></P> <P>The hydrogen embrittlement (HE) and H trapping sites of pearlitic steel specimens with various lamellar spacings (λ) were evaluated through slow strain rate tensile testing and thermal desorption analysis. When λ decreases, both tensile strength and resistance to HE were unusually improved. This is because tearing, which is the initiation of H cracking, was delayed in the specimen with fine λ and short cementite (θ) platelets. Undeformed H-charged specimens showed a peak (peak 1), which is separable into two sub-peaks (peak 1-1 and peak 1–2) in their H desorption rate curves, regardless of λ. Peak 1-1 and peak 1–2 were generated by H atoms detrapped from F<SUB>P</SUB>/θ interfaces and from dislocations inside F<SUB>P</SUB>, respectively. The <I>E</I> <SUB> <I>a</I> </SUB> values of H desorption for peak 1-1 and peak 1–2 were 23.2 kJ/mol, and 26.1 kJ/mol, respectively. Meanwhile, deformed H-charged specimens exhibited the second peak (peak 2) with peak temperature (T<SUB>P</SUB>) of ∼600 K, as well as peak 1 with T<SUB>P</SUB> of ∼375 K. When tensile strain increased, peak 2 increased at the expense of peak 1. Primary H trapping sites for peak 2 are strained F<SUB>P</SUB>/θ interfaces with interfacial dislocations.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Effects of the Anti-sepsis Drug, (S)-1-(α-Naphthylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (CKD-712), on Mortality, Inflammation, and Organ Injuries in Rodent Sepsis Models

Jae-Hwan Park,Dal-hyun Kim,In-Chang Hwang,Nina Ha,Sera Lee,Jung Min Kim,Sung Sook Lee,Hosung Yu,In-Taek Lim,Jun-A You 대한약학회 2011 Archives of Pharmacal Research Vol.34 No.3

CKD-712 is a 1-naphthyl analog of higenamine that has been reported to have potent antiinflammatory and thus anti-sepsis effects. The purpose of this study was to investigate the potential of CKD-712 as a medicine for sepsis and to confirm its protective effects on organs in animal sepsis models. Pretreatment with CKD-712 dose-dependently increased survival rate in a lipopolysaccharide-induced sepsis model in mice. Body temperature decrease, an important pre-symptom of septic death, was also prevented by CKD-712. CKD-712 still significantly increased survival rate even when administered one and four hours after lipopolysaccharide injection. Therapeutic efficacy of CKD-712 was also confirmed against sepsis following zymosan-induced endotoxemia and in cecal ligation and puncture surgery in mice. In a disseminated intravascular coagulation model in rats, CKD-712 showed organ-protective effect by reducing serum glutamate-oxaloacetate transaminase, glutamate-pyruvate transferase, blood urea nitrogen, and creatinine levels. CKD-712 also prevented histological damage to the lung and liver. In this same model, CKD-712 showed anti-inflammatory effects through decreases in tumor necrosis factor-α and interleukin-6 in the blood and reduced translocation of nuclear factor-κB to the nuclei of lung cells. CKD-712 administration also diminished infiltration of leukocytes into the lung and liver. Taken together, these results show that CKD-712 has excellent potential as an effective medicine for sepsis.

Clinicopathological characteristics and prognostic factors in combined hepatocellular carcinoma and cholangiocarcinoma

Sang Eun Park,Sung Ha Lee,Jae Do Yang,Hong Pil Hwang,Si Eun Hwang,Hee Chul Yu,Woo Sung Moon,Baik Hwan Cho 한국간담췌외과학회 2013 한국간담췌외과학회지 Vol.17 No.4

Backgrounds/Aims: Combined hepatocellular carcinoma and cholangiocarcinoma (cHCC-CC) is an uncommon subtype of primary liver cancer that has rarely been reported in detail. This study was performed in order to evaluate the clinicopathological characteristics and prognostic factors of cHCC-CC in single center. Methods: The clinicopathological features of patients diagnosed and operated with cHCC-CC at Chonbuk National Hospital between July 1998 and July 2007 were retrospectively studied by comparing them with patients with only hepatocellular carcinoma (HCC) who had undergone a hepatic resection during the same period. Results: Ten out of 152 patients who had undergone a hepatic resection were diagnosed with cHCC-CC and thus included in this study (M : F=8 : 2, median age: 52±11.1 years). According to the parameters of the 7th American Joint Committee on Cancer T staging, there were 76 (50.0%), 44 (28.9%), 9 (5.9%), 18 (11.8%) and 5 (3.3%) patients with T stages 1, 2, 3a, 3b and 4, respectively. The overall survival period was longer in the HCC only group (68±40.4 months) than in the combined cHCC-CC group (23±40.1 months) (p<0.0001). The 5-year survival rate was 10% in the cHCC-CC group and 60% in the HCC group (p<0.0001). The disease free survival for patients with cHCC-HCC and HCC were 16±37.4 and 51±44.3 months, respectively (p<0.0001). Univariate analysis revealed that age, gender, transarterial chemoembolization (TACE), and T stage were statistically significant in terms of patient’s overall survival. However, there were no significant clinicopathological factors identified by the multivariate analysis. Conclusions: Even after the hepatic resection in the HCC, the prognosis is poorer if the patient has cholangiocellular components compared to the usual HCC.