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- 저자 : JIANFANG JIANG (검색결과 1 건)
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PREPARATION AND PROPERTY STUDIES OF Zn 3 P 2 /CALCIUM ALGINATE
JIANFANG JIANG,HAIXIN CUI,YU CAO 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2014 NANO Vol.9 No.2
Zn 3 P 2 is an acute and e®ective rodenticide used widely to protect grains in stores and domes-tically to kill rodents. This study aims to postpone the time of poisoning symptoms after eatingZn 3 P 2 and improve the e®ect of killing rodents. Zn 3 P 2 /calcium alginate (Zn 3 P 2 /CA) was syn-thesized through the reaction of sodium alginate and calcium chloride by the reversed-phasemicroemulsion method and then loaded with Zn 3 P 2 technical. It was characterized by X-raydi®ractometer, laser particle size analyzer, scanning electron microscope (SEM) and transmissionelectron microscopy (TEM). The drug loading capacity, slow-controlled release performances andtoxic e®ects were also investigated. The results showed that Zn 3 P 2 /CA was spherical, averageparticle size was 353.9 nm, and particle dispersion index (PDI) was 0.195. The mass ratios ofcalcium alginate and Zn 3 P 2 technical (CA/Zn 3 P 2 ) had signi¯cant impacts to drug loading ca-pacity and slow-controlled release performances of Zn 3 P 2 /CA. The palatability and e±cacy ofZn 3 P 2 /CA were signi¯cantly improved and enhanced compared with Zn 3 P 2 technical. The resultsshowed that Zn 3 P 2 /CA presented high loading e±ciency, commendable sustained-release per-formance and good environmental compatibility, and this delivery carrier may be extended toother slow-controlled release and high-e±cient pesticide formulation in future.
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