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Ock, C. Y.,Oh, D. Y.,Lee, J.,Kim, T. Y.,Lee, K. H.,Han, S. W.,Im, S. A.,Kim, T. Y.,Bang, Y. J. Springer Science + Business Media 2016 Gastric cancer Vol.19 No.2
<P>Weight loss during chemotherapy is a significant prognostic factor for poor survival in patients with advanced gastric cancer (AGC). However, in most studies, weight loss was measured at the end of chemotherapy, limiting its clinical use. In this study, we evaluated whether weight loss during the first month of chemotherapy could predict survival outcomes in patients with AGC. We analyzed 719 patients with metastatic or recurrent AGC who were receiving palliative chemotherapy. We calculated the initial body mass index (BMIi), percent weight loss after 1 month of chemotherapy (Delta W (1)m), percent weight loss after last administration of chemotherapy (Delta W (end)), and average weight loss per month during chemotherapy (Delta W/m). We correlated these data with overall survival (OS) by receiver-operating characteristic (ROC) curves and Kaplan-Meier curves, and performed a subgroup analysis using Cox regression. The probabilities of longer OS had stronger correlations with Delta W/m and Delta W (1)m than with Delta W (end) or BMIi. A significant positive correlation between Delta W (1)m and Delta W/m (r (2) = 0.591, p < 0.001) was observed. Median OS of patients with Delta W (1)m more than 3 % was significantly shorter than in patients with less weight loss (OS: 9.7 vs. 16.3 months, p < 0.001). Subgroup analysis revealed that Delta W (1)m accompanied poor survival irrespective of other clinical characteristics. Weight loss at the very first month of palliative chemotherapy could predict unfavorable survival outcomes in AGC.</P>
LCD 이송장치 Column 부의 식스 시그마 강건설계를 위한 연구
정동원(D. W. Jung),정원지(W. J. Chung),송태진(T. J. Song),방덕제(D. J. Bang),윤영민(Y. M. Yoon) 한국정밀공학회 2005 한국정밀공학회 학술발표대회 논문집 Vol.2005 No.10월
This research studied robust design of column part for LCD transfer system. 1<SUP>st</SUP> DOE(Design of Experiment)was conducted to find out main effect factors. 36 experiments were performed and their results were shows that the geometric parameters(Low-length, Side-length, Upper-thickness, Middle-thickness)are more important than other factors. The main effect plots shows that the maximum deflection of column is minimized with increasing Low-length, Side-length, underthickness and Middle-thickness. 2<SUP>nd</SUP> DOE was conducted to obtain RMS(Response Surface Method)equation 25 experiments were conducted. The CCD(Central Composite Design)technique with four factors were used. The coefficient of determination (R²) for the calculated RSM equation was 0.986. Optimum design was conducted using the RSM equation Multi-island genetic algorithm was used to optimum design. Optimum value for Low-length, Side-length, Upper-thickness and Middle-thickness were 299.8㎜, 180.3㎜, 21.7㎜, 21.9㎜ respectively. An approximate value of 5.054㎜ in deflection was expected to be a maximum under the optimum conditions. Six sigma robust design was conducted to find out guideline for control range of design parameter. To acquire six sigma level reliability, the standard deviation of design parameter should be controlled within 2% of average design value.
Bang, H.W.,Yoo, W.,Choi, Y.,You, C.Y.,Hong, J.I.,Dolinsek, J.,Jung, M.H. Elsevier 2016 CURRENT APPLIED PHYSICS Vol.16 No.1
<P>The tetragonal Mn3Ga films exhibited high perpendicular magnetic anisotropy, low saturation magnetization, and high spin polarization, which satisfy the criteria of spin-transfer-torque based devices. For practical device applications, it is necessary to improve the interface nature and optimize the deposition conditions. We fabricated thin films of tetragonal Mn3Ga directly on MgO(100) without any buffer layer by using DC/RF magnetron sputtering method. We investigated the crystallinity, microstructure, and magnetic properties with varying the deposition conditions; such as deposition temperature (350 -450 degrees C), RF power (25-40 W), and Ar gas pressure (2-7 mTorr). X-ray diffraction data revealed that the growth direction is perpendicular to the film plane, i.e., the c axis. Scanning electron microscope images showed that the top surface is flat with a maximum thickness of 290 nm. The optimal deposition conditions are 400 degrees C, 35 W, and 5 mTorr in our sputtering system. For the field perpendicular to the film plane, clear hysteresis loop was observed with the saturation magnetization M-S - 100 emu/cc at room temperature. By extrapolating the hard magnetization data for the field parallel to the film plane, the anisotropic energy was estimated about K-1 = 1 x 10(6) J/m(3). (C) 2015 Elsevier B.V. All rights reserved.</P>