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An Oxepinoflavone from Artocarpus elasticus with Cytotoxic Activity Against P-388 Cells
Iqbal Musthapa,Lia D. Juliawaty,Yana M. Syah,Euis H. Hakim,Jalifah Latip,Emilio L. Ghisalberti 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.2
A new oxepinoflavone, artoindonesianin E1 (1), was isolated from the wood of Artocarpus elasticus,along with four known prenylated flavones: artocarpin (2), cycloartocarpin (3), cudraflavones A (4) andC (5). The structure of the new compound was identified by spectroscopic methods. Upon cytotoxic evaluation against murine leukemia P-388 cells, the new compound showed IC50 5.0 μg/mL.