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Yoo, Il-Sou,Choi, Kyung-Soon,Ryu, Mun-Hee Korean Society of Environmental Health 2008 한국환경보건학회지 Vol.34 No.4
This study was performed to investigate the effects of Chitosan on the nickel poisoning in rats. In the study, 150 male Sprague-Dawley were used. The experimental groups were divided into four: A (30 mg/L nickel), B (30 mg/L nickel+0.2% Chitin, Chitosan and Dithiocarbamate Chitosan), C (30 mg/L nickel+0.4% Chitin, Chitosan and Dithiocarbamate Chitosan), D (30 mg/L nickel+0.8%Chitin, Chitosan and Dithiocarbamate Chitosan). The results were as flows; 1. The nickel concentration in the livers of the control group (A) was $0.153{\sim}0.186\;mg/kg$ but the nickel concentration in the livers of the experimental decreased during the experimental period (P<0.05). 2. Metallothionenin levels in rat liver were $2.77{\sim}3.25\;ug/g$ wet,wt in control group (A), but were $2.89{\sim}3.51\;ug/g$ wet,wt (B), $2.97{\sim}3.62\;ug/g$ wet,wt (C), $2.68{\sim}3.68\;ug/g$ wet,wt (D). Respectively in the experimental groups. The experimental groups were inclined to increase compare to the control group (P<0.05). In conclusion, this study revealed a preventive effect of Chitin, Chitosan and Dithiocarbamate Chitosan against nickel toxicity.
The Effect of Selenium and Chitosan on the Cadmium Toxicity in Rat Hairs and Liver
( Il Sou Yoo ),( Kyung Soon Choi ),( Jong Soon Lee ) 한국조직공학·재생의학회 2008 조직공학과 재생의학 Vol.5 No.4
The object of this work is to investigate that chitosan and selenium influence to rat`s cadmium toxicity and it helped to conclude like these with experiments which is finding what influence is taken chitosan and selenium to rat`s hair and liver. (1) To compare with the county of only eaten cadmium(control group) and the county of eaten chitosan and selenium in mix, the capacity of condensed cadmium at rat`s liver in county of investigating is lower than control group with mindful gap.(P < 0.05) (2) It showed lower value at the capacity of condensed in county of investigating than control group within albino rat`s hair and yet there is not mindful gap. (3) It showed higher value at the capacity of condensed metallothionein in county of investigating than control group(B) and there is mindful gap.(P < 0.05) (4) For measuring of glutathione-s-transferase activity within rat`s liver we made the county what albino rat eat feed mixed with 0.03% cadmium. And the result showed higer value of investigating county than control group(B) and yet there is not mindful gap. (5) At comparing of county of only eaten cadmium and county of eaten chitosan and selenium in mix with measurement of glutathione-peroxidase activities in albino rat`s liver, we can see the mindful gap.(P < 0.05) With allover results like these, we can know about eating chitosan and selenium in mix is effective at counteract of poisonous within rat`s hair and liver.
만경강 지류에 서식하는 Unio Douglasiae 의 중금속 함량에 관한 조사연구
유일수,김환홍 ( Il Sou Yoo,Hwan Hong Kim ) 한국하천호수학회 1991 생태와 환경 Vol.24 No.2
For this survey, Unio douglasiae was collected from six station in Mangyung River from October 1987 to October 1990. The contents of Cd, Pb, Cr, Cu and Zn in edible portion of Unio douglasiae were analyzed. The results obtained are as follows; The contents of heavy metals in Unio douglasiae shoued in the range of 0.03∼0.34 ppm for Cd, 0.18∼1.69 ppm for Pb, 0.04∼0.38 ppm for Cr, 0.38∼1.24 ppm for Cu, 1.94∼3.24 ppm for Zn. As a whole, contents of heavy metals contained in Unio douglasiae from the lower course of the Jeon Ju Chon were larger than those from the upper course. But those was little difference between the contents of heavy metal at E site and F site.
구태규 ( Tae Kyu Ku ),유일수 ( Il Sou Yoo ),박안나 ( An Na Park ) 한국미용학회 2014 한국미용학회지 Vol.20 No.5
In this study was to examine the applicability of mango (MangiferaindicaL.) leaf extract to cosmetics a composition based on its antioxidant activity. Extracted with ethanol and water to obtain a 50% concentration of mango leaf extract (0.4, 2, 10, 50 mg/ml) as mango leaf collected in Jeju Island, Korea. In 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical assay, lower concentrations of mango leaf extract resulted in a dose-dependent increase in antioxidant activity compared to the synthetic antioxidant butylated hydroxytoluene (BHT). Total polyphenol and flavonoid contents were highest in the 50 mg/mL mango leaf extract. Cell viability and cytotoxicity were assessed in RAW 264.7 cells by ROS production, macrophages were exposed to various concentrations (10, 25, and 50 μL) of mango leaf extract. Reduced DCF fluorescence intensities indicating stronger antioxidant activities were observed in a mango leaf extract concentration-dependent manner. Nitrite scavenging activity also increased with higher concentrations of mango leaf extract, thus demonstrating the ability of mango leaf extract to inhibit nitrosamine production. Based on these results, mango leaves have excellent antioxidant activity and are safe to be incorporated and used as a component of cosmetics a composition.
송지홍(Ji Hong Song),유근재(Keun Jai Yoo),송인옥(In Ok Song),백은찬(Eun Chan Paik),최범채(Bum Chae Choi),궁미경(Mi Kyoung Koong),손일표(Il Pyo Son),전종영(Jong Young Jun),강인수(Inn Soo Kang),박인서(In Sou Park) 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.11
N/A Objeetive: Ovarian hyperstimulation syndrome (OHSS) is one of the well known complication of conttolled ovarian hyperstimulation. Though there have been numerous protocols for the prevention of OHSS, it has not been completely preventable until now. This study was performed to identify clinical predictors for early and late OHSS. Methods: A retrospective analysis of all IVF cycles in 1993 up to June 1996 was performed. OHSS was diagnosed using the criteria of Rabau modified by Schenker. All cases of OHSS reported in this study presented with marked ovarian enlargement, ascites, oliguria, hemoconcentration and electrolyte disturbance. Ovarian stimulation was carried out using a combination of gonadotrophin releasing hormone-agonist, follicle-stimulation hormone and human menopausal gonadotrophin. 27 patients has moderate or severe OHSS presenting 3-7 days post-human chorionic gonadotrophin (hCG), and 21 patients had severe OHSS presenting 12-17 days post-hCG. Results: No patient with early OHSS went onto develop late OHSS, and no patient with late OHSS had demonstrated early OHSS. Logistic regression showed that early OHSS was predicted by the number of oocytes retrieved and the estradiol concentration on the day hCG injection (P<0.05). Late OHSS was predicted by the transferred embryos, B-hCG on 14 day after hCG injection (P<0.05). Conclusion: Early OHSS was an acute effect of the hCG administered prior to egg retrieval in women with high estradiol and large number of retrieved oocytes. Our analysis of the risk factors for early OHSS indicates that cryopreservation of all embryos will not alter the risk of early OHSS even though it should prevent late OHSS. Late OHSS was induced by the rising serum concentration of hCG produced by the early pregnancy, the number of transferred embryos must be adjusted carefully, since it was associated with multiple gestation.
습관성유산 및 불임환자에서 자궁중격절제술 후 임신의 결과
송지홍(Ji Hong Song),유근재(Keun Jai Yoo),송인옥(In Ok Song),백은찬(Eun Chan Paik),최범채(Bum Chae Choi),손일표(Il Pyo Son),전종영(Jong Young Jun),박인서(In Sou Park),궁미경(Mi Kyoung Koong),강인수(In Soo Kang) 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.12
N/A Uterine anomalies have been reported in 4% of women with infertility and in up to 15% of those with recurrent abortion. One of the major intrauterine disorder associated with infertility and recurrent abortions is intrauterine septum, The reproductive outcome of 41 patients of intrauterine septum (7 complete, 34 incomplete) with repeated abortions or infertility was assessed after the uterine septotomy. 5 of 7 patients with comlete uterine septum undergone uterine septotomy (3; hysteroscopic metroplasty, 2; abdominal metroplasty) had total 6 pregnancies and all of them had live biths. 28 patients with incomplete uterine septum got the hysteroscopic intrauterine septotomy and the viable pregnancy rate was 62% (3 ongoing pregnancies, 13 live biths of total 26 pregnancies). 6 patients with incomplete uterine septum had not the operation and 5 patients had 5 live births after total 6 pregnancies with 1 spontaneus abortion. Even though, the number of cases were small, the live birth rate in the group of septotomy of the patients of complete uterine septum (100%, 6/6) was higher than that in the group of not-done (50%, 1/2). The live birth rate in the group of not-done of the patients with incomplete uterine septum (83%, 5/6) was higher than that in the group of hysteroscopic uterine septotomy (62%, 16/26), but 5 of 6 had short uterine septal length (<1 cm), 1 had 1.5 cm septal length in the group of not-done. All the patients with successful pregnancy outcome had no other co-factors at the diagnostic laparoscopy, but the 5 primary infertility patients with no live birth even after treatment (all were with incomplete septum; 3 undergone hysteroscopic septotomy, 2 not-done with one abortion) had other co-factors such as endometriosis, peritoneal or tubal facor. In conclusion, hysteroscopic uterine septotomy would be useful for the patients with habitutal abortion or infertility and more advanced managemnet protocols should be applied to the patients having other co-factors if there was no pregnancy even after the uterine septotomy.