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Hyo-Jung Park,Jun-Kyum Kim,Hye-Min Jeon,Se-Yeong Oh,Sung-Hak Kim,Do-Hyun Nam,Hyunggee Kim 한국분자세포생물학회 2011 Molecules and cells Vol.31 No.2
This paper was initially submitted to Journal ‘Molecules and Cells’ without approval from two coauthors. According to the decision of editorial committee, I, as a corresponding author for this paper, withdraw authorship of two coauthors who did not agree to use of XO1, XO2, and XO3 cells shown in Fig. 1B. Thus, we change data shown in Fig. 1B by removing expression of TLX in these cells. We deeply regret this circumstance and apologize to the community.
Hyo-Jung Park,Jun-Kyum Kim,Hye-Min Jeon,Se-Yeong Oh,Sung-Hak Kim,Myung-Jin Park,Akio Soeda,Do-Hyun Nam,김형기 한국분자세포생물학회 2010 Molecules and cells Vol.30 No.5
A growing body of evidence indicates that deregulation of stem cell fate determinants is a hallmark of many types of malignancies. The neural stem cell fate determinant TLX plays a pivotal role in neurogenesis in the adult brain by maintaining neural stem cells. Here, we report a tumorigenic role of TLX in brain tumor initiation and progression. Increased TLX expression was observed in a number of glioma cells and glioma stem cells, and correlated with poor survival of patients with gliomas. Ectopic expression of TLX in the U87MG glioma cell line and Ink4a/Arfdeficient mouse astrocytes (Ink4a/Arf-/- astrocytes) induced cell proliferation with a concomitant increase in cyclin D expression, and accelerated foci formation in soft agar and tumor formation in in vivo transplantation assays. Furthermore,overexpression of TLX in Ink4a/Arf-/- astrocytes inhibited cell migration and invasion and promoted neurosphere formation and Nestin expression, which are hallmark characteristics of glioma stem cells, under stem cell culture conditions. Our results indicate that TLX is involved in glioma stem cell genesis and represents a potential therapeutic target for this type of malignancy.
Jeon, Hyo Sang,Jee, Michael Shincheon,Kim, Haeri,Ahn, Su Jin,Hwang, Yun Jeong,Min, Byoung Koun American Chemical Society 2015 ACS APPLIED MATERIALS & INTERFACES Vol.7 No.44
<P>Oxygen evolution reaction (OER) is the key reaction in electrochemical processes, such as water splitting, metal–air batteries, and solar fuel production. Herein, we developed a facile chemical solution deposition method to prepare a highly active Co<SUB>3</SUB>O<SUB>4</SUB> thin film electrode for OER, showing a low overpotential of 377 mV at 10 mA/cm<SUP>2</SUP> with good stability. An optimal loading of ethyl cellulose additive in a precursor solution was found to be essential for the morphology control and thus its electrocatalytic activity. Our results also show that the distribution of Co<SUB>3</SUB>O<SUB>4</SUB> nanoparticle catalysts on the substrate is crucial in enhancing the inherent OER catalytic performance.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/aamick/2015/aamick.2015.7.issue-44/acsami.5b06189/production/images/medium/am-2015-06189z_0010.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/am5b06189'>ACS Electronic Supporting Info</A></P>
Jeon, Eun-Beom,Ahn, SangKeun,Lee, In-Gyu,Koh, Hyo-In,Park, Junhong,Kim, Hak-Sung Elsevier 2015 COMPOSITE STRUCTURES -BARKING THEN OXFORD- Vol.134 No.-
<P><B>Abstract</B></P> <P>In this paper, the mechanical/dynamic property of the carbon fiber reinforced polymer concrete (CFRPC) was investigated to reduce the vibration/noise problems on rail slab. The CFRPC was fabricated with the different weight fraction of carbon fiber and different fiber length. The oxygen plasma treatment was performed to enhance the adhesion between the carbon fiber and epoxy resin. The surface of the carbon fiber with the oxygen plasma treatment was characterized using X-ray photoelectron spectroscopy (XPS) analysis and scanning electron microscope (SEM). The flexural strength of the CFRPC was measured using 3-point bending test. Also, the frequency dependent variation of the stiffness and damping of the CFRPC were measured by impact test to characterize their ability to reduce the vibration. In this study, the CFRPC with 12mm of optimal fiber length and 2wt% of the optimal fiber content showed 25.12MPa flexural strength and 0.01954 damping value. Finally, it was found that the noise level of the railway using CFRPC sleeper was decreased by 4dB compared to that using the polymer concrete sleeper, from the impact test of the scaled model of the railway structure.</P>