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Solid forms of pharmaceuticals: Polymorphs, salts and cocrystals
Bipul Sarma,Allan S. Myerson,Jie Chen,Huai-Ying Hsi 한국화학공학회 2011 Korean Journal of Chemical Engineering Vol.28 No.2
Control and selection of the properties of active pharmaceutical ingredients is a crucial part of the drug development process. One major part of this process is the selection of an appropriate solid form. This review will discuss three major types of crystalline solids, polymorphs, salts and cocrystals and processes used to develop and find these forms.