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      • SCIESCOPUSKCI등재

        Research on a New 12-Pulse Step-Up and Step-Down Aviation Auto-Transformer Rectifier

        Jiang, Fan,Ge, Hong-juan,Dong, Xiao-xu,Zhang, Lu The Korean Institute of Power Electronics 2018 JOURNAL OF POWER ELECTRONICS Vol.18 No.1

        This paper presents a new step-up and step-down multi-pulse auto-transformer rectifier unit (ATRU) topology. This structure can achieve a wide range of output voltages, which solves the problem of auto-transformer output voltage being difficult to regulate. Adding middle taps to the primary winding and reasonably setting the number of auto-transformer windings, constituted two groups of three-phase output voltages with a $30^{\circ}$ phase difference. Multi-pulse output DC voltage is obtained after a three-phase output voltage across two rectifier bridges and inter-phase reactor. Thus, the output DC voltage is related to the number and configuration of the auto-transformer winding. In this paper, the relationship between the voltage ratio of the auto-transformer and the ratio of winding, input current and auto-transformer kilovoltampere rating are deduced and validated by simulations. On this basis, the output voltage range is optimized. An experiment on two different voltage ratio principle prototypes was carried out to verify the correctness of the analysis design.

      • SCIESCOPUSKCI등재

        Step-up and Step-down Asymmetrical 24-Pulse Autotransformer Rectifier

        Zhang, Lu,Ge, Hong-juan,Jiang, Fan,Yang, Guang,Lin, Yi The Korean Institute of Power Electronics 2018 JOURNAL OF POWER ELECTRONICS Vol.18 No.5

        The existing 24-pulse autotransformer rectifier unit (ATRU) needs interphase reactors for parallel work of the rectifier bridges, and its output voltage cannot be regulated. Aiming at these problems, a step-up and step-down asymmetrical 24-pulse ATRU is proposed in this paper. The connections and turns ratios among transformer windings are well designed. In addition, a 15-degree phase difference is formed between two of the 24 voltage vectors produced by the transformer, which makes the four rectifier bridge groups produce a 24-pulse DC voltage without interphase reactors. Meanwhile, by adding extended winding to each phase of the transformer, wide-range regulation of the ATRU output voltage can be realized, and the reasonable voltage regulation range is between 0.2 and 1.6. The superposition of the voltage vectors and the principle of the voltage regulation are analyzed in detail. Furthermore, the turns ratio of the windings, winding current, output voltage, and kilovolt-ampere rating are all derived. Finally, the simulations and experiments are carried out, and the correctness of the principle and theoretical analysis of the new 24-pulse ATRU are verified.

      • CCNG2 Suppressor Biological Effects on Thyroid Cancer Cell through Promotion of CDK2 Degradation

        Li, Wei-Juan,Liu, Ge-Ling,Yu, Fang,Xiang, Xiu-Xiu,Lu, Yi-Fang,Xiao, Hong-Zhen,Shi, Yan-Ping Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.10

        This study aimed to analyze the expression and clinical significance of cyclin G2 (CCNG2) in thyroid carcinoma and the biological effects of CCNG2 overexpression in a cell line. Immunohistochemistry and Western blotting were used to analyze CCNG2 protein expression in 63 cases of thyroid cancer and normal tissues to allow the relationship with clinical factors to be assessed. CCNG2 lentiviral and empty vectors were transfected into the thyroid cancer K1 cell line. Reverse transcription-polymerase chain reaction (RT-PCR) and Western blotting were applied to detect the mRNA and protein levels of CCNG2. MTT assay and cell cycle were also conducted to assess the influence of up-regulated expression of CCNG2 on K1 cell biology. The level of CCNG2 protein expression was found to be significantly lower in thyroid cancer tissue than normal tissues (P<0.05). Western blot: The relative amount of CCNG2 protein in thyroid cancer tissue was respectively found to be significantly lower than in normal tissues (P<0.05), correlating with lymph node metastasis, clinic stage and histological grade (P<0.05), but not gender, age or tumor size (P>0.05). Loss of CCNG2 expression correlated significantly with poor overall survival time on Kaplan-Meier analysis (P<0.05). The results for biological functions showed that K1 cell transfected CCNG2 had a lower survival fraction, a greater percentage in the G0/G1 phases, and lower cyclin-dependent kinase 2 (CDK2) protein expression compared with K1 cells non-transfected with CCNG2 (P<0.05). CCNG2 expression decreased in thyroid cancer and correlated significantly lymph node metastasis, clinic stage, histological grade and poor overall survival, suggesting that CCNG2 may play important roles as a negative regulator in thyroid cancer K1 cells by promoting degradation of CDK2.

      • KCI등재

        Step-up and Step-down Asymmetrical 24-Pulse Autotransformer Rectifier

        Lu Zhang,Hong-juan Ge,Fan Jiang,Guang Yang,Yi Lin 전력전자학회 2018 JOURNAL OF POWER ELECTRONICS Vol.18 No.5

        The existing 24-pulse autotransformer rectifier unit (ATRU) needs interphase reactors for parallel work of the rectifier bridges, and its output voltage cannot be regulated. Aiming at these problems, a step-up and step-down asymmetrical 24-pulse ATRU is proposed in this paper. The connections and turns ratios among transformer windings are well designed. In addition, a 15-degree phase difference is formed between two of the 24 voltage vectors produced by the transformer, which makes the four rectifier bridge groups produce a 24-pulse DC voltage without interphase reactors. Meanwhile, by adding extended winding to each phase of the transformer, wide-range regulation of the ATRU output voltage can be realized, and the reasonable voltage regulation range is between 0.2 and 1.6. The superposition of the voltage vectors and the principle of the voltage regulation are analyzed in detail. Furthermore, the turns ratio of the windings, winding current, output voltage, and kilovolt-ampere rating are all derived. Finally, the simulations and experiments are carried out, and the correctness of the principle and theoretical analysis of the new 24-pulse ATRU are verified.

      • SCIESCOPUSKCI등재

        Unbalance Control Strategy of Boost Type Three-Phase to Single-Phase Matrix Converters Based on Lyapunov Function

        Xu, Yu-xiang,Ge, Hong-juan,Guo, Hai The Korean Institute of Power Electronics 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.1

        This paper analyzes the input side performance of a conventional three-phase to single-phase matrix converter (3-1MC). It also presents the input-side waveform quality under this topology. The suppression of low-frequency input current harmonics is studied using the 3-1MC plus capacitance compensation unit. The constraint between the modulation function of the output and compensation sides is analyzed, and the relations among the voltage utilization ratio and the output compensation capacitance, filter capacitors and other system parameters are deduced. For a 3-1MC without large-capacity energy storage, the system performance is susceptible to input voltage imbalance. This paper decouples the inner current of the 3-1MC using a Lyapunov function in the input positive and negative sequence bi-coordinate axes. Meanwhile, the outer loop adopts a voltage-weighted synthesis of the output and compensation sides as a cascade of control objects. Experiments show that this strategy suppresses the low-frequency input current harmonics caused by input voltage imbalance, and ensures that the system maintains good static and dynamic performances under input-unbalanced conditions. At the same time, the parameter selection and debugging methods are simple.

      • Microstructure and Bonding Strength of Tungsten Coating Deposited on Copper by Plasma Spraying

        Song Shu-Xiang,Zhou Zhang-Jian,Du Juan,Zhong Zhi-Hong,Ge Chang-Chun 한국분말야금학회 2006 한국분말야금학회 학술대회논문집 Vol.2006 No.1

        Tungsten coatings with different interlayers onto the oxygen-free copper substrates were fabricated by atmosphere plasma spraying. The effects of different interlayers of NiCrAl, NiAl and W/Cu on bonding strength were studied. SEM, EDS and XRD were used to investigate the photographs and compositions of these coatings. The tungsten coatings with different initial particle sizes resulted in different microstructures. Oxidation was not detected in the tungsten coating, but in the interlayer, it was found by both XRD and EDS. The tungsten coating deposited directly onto the copper substrate presented higher bonding strength than those with different interlayers.

      • Susceptibility Loci Associations with Prostate Cancer Risk in Northern Chinese Men

        Wang, Na-Na,Xu, Yong,Yang, Kuo,Wei, Dong,Zhang, Yao-Guang,Liu, Ming,Shi, Xiao-Hong,Liang, Si-Ying,Sun, Liang,Zhu, Xiao-Quan,Yang, Yi-Ge,Tang, Lei,Zhao, Cheng-Xiao,Wang, Xin,Chen, Xin,Hui, Juan,Zhang, Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.5

        Background: KLK3 gene products, like human prostate-specific antigen (PSA), are important biomarkers in the clinical diagnosis of prostate cancer (PCa). G protein-coupled receptor RFX6, C2orf43 and FOXP4 signaling plays important roles in the development of PCa. However, associations of these genes with PCa in northern Chinese men remain to be detailed. This study aimed to investigate their impact on occurrence and level of malignancy. Methods: All subjects were from Beijing and Tianjin, including 266 cases with prostate cancer and 288 normal individuals as controls. We evaluated associations between clinical covariates (age at diagnosis, prostate specific antigen, Gleason score, tumor stage and aggressive) and 6 candidate PCa risk loci, genotyped by PCR- high resolution melting curve and sequencing methods. Results: Case-control analysis of allelic frequency of PCa associated with PCa showed that one of the 6 candidate risk loci, rs339331 in the RFX6 gene, was associated with reduced risk of prostate cancer (odds ratio (OR) = 0.73, 95% confidence interval (CI) =0.57-0.94, P = 0.013) in northern Chinese men. In addition, subjects with CX (CC+TC) genotypes had a decreased risk for prostrate cancer compared to those carrying the TT homozygote (OR =0.64, 95% CI = 0.45- 0.90, P = 0.008). The TT genotype of 13q22 (rs9600079, T) was associated with tumor stage (P=0.044, OR=2.34, 95% CI=0.94-5.87). Other SNPs were not significantly associated with clinical covariates in prostate cancer (P > 0.05). Conclusions. rs339331 in the RFX6 gene may be associated with prostate cancer as a susceptibility locus in northern Chinese men.

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