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- 저자 : Hong-Fu Hou (검색결과 3 건)
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Hong Chang,Jiang Long Guo,Xiao Wei Fu,Xiu Jing Shen,Youming Hou,Kongming Wu 한국응용곤충학회 2018 Journal of Asia-Pacific Entomology Vol.21 No.4
Cryptochrome (CRYs) proteins have been elucidated as the molecular basis for magnetoreception in Drosophila, and a putative magnetic receptor (named IscA1) protein may aslo be involved in sensing magnetic fields in Drosophila. However, whether IscA1 has a conserved role in diverse animals and functions in orientation during animal migration is unknown. Here we report on the cloning and sequencing of the IscA1 gene from Agrotis segetum, which encodes a predicted protein IscA1 that has 131 amino acids and two conserved iron-sulphur cluster binding domains. Multiple sequence alignment and phylogenetic analysis were used to show that IscA1 had a relatively high homology from species of Noctuoidea. Quantitative polymerase chain reaction showed that IscA1 was ubiquitously expressed in adult organs and, among all developmental stages, expression was higher in adults. When Agrotis segetum was exposed to 14 h light/10 h dark, IscA1 expression also showed daily oscillations, and constant light or dark disturbed these oscillations. IscA1 expression levels in a migratory population were higher than in a reared population and higher in a southward migratory population than in a northward. These findings suggest that the IscA1 gene in A. segetum might be associated with migration and provide a molecular basis for further study on the functions of IscA1 gene in magnetoreception and potential control of the turnip moth.
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Upregulation of MicroRNA 181c Expression in Gastric Cancer Tissues and Plasma
Cui, Mei-Hua,Hou, Xiao-Lin,Lei, Xiao-Yan,Mu, Fang-Hong,Yang, Gui-Bin,Yue, Lin,Fu, Yi,Yi, Guo-Xing Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.5
Objective: To test the microRNA-181c (miR-181c) expression in tissues and plasma of gastric cancer (GC) cases, analyze any correlations, and explore the possibility of miR-181c as a potential molecular marker for GC diagnosis. Materials and Methods: Relative miR-181c expression levels in cancers and plasma from 30 GC patients was tested using reverse transcription-real-time fluorescent quantitation PCR and compared to that in samples from 30 gastric ulcer and 30 chronic gastritis patients. Results: The miR-181c expression level in the GC tissues was significantly higher than that in the gastric ulcer and chronic gastritis tissues (P = 0.000), as was the miR-181c expression level in the GC plasma (P = 0.000). We determined that miR-181c expression in GC plasma was positively correlated to its expression in the GC tissues (P = 0.000). Conclusions: The expression of miR-181c is upregulated in GC tissues and plasma, and the miR-181c expression level in GC plasma is positively correlated to that in the corresponding cancer tissues. Plasma miR-181c is possibly a new serological marker for GC diagnosis.
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Thermal Deformation Isolation for Satellite Platforms via Flexible Connections
Zheng-Chun Du,Hong-Fu Hou,Zhi-Guo Wang,Jian-Guo Yang 한국정밀공학회 2017 International Journal of Precision Engineering and Vol.18 No.12
Thermal deformation is a serious issue for many space structures when travelling around Earth. This paper presents a method to achieve extremely low thermal deformation in satellite platforms with prototype applications. In addition to using the traditional nearzero coefficient of thermal expansion (CTE) material, the platform succeeded in comparison to the traditional energy-consuming methods mainly due to the unique isolation of the residual thermal expansion by flexible connections. First, the design of the composite with near-zero CTE is briefly introduced and used to develop the precision satellite platform. Next, the isolation mechanism to minimize the thermal deformation is presented. Then, the deformation isolation is detailed through the “flexible connecting” method. The effectiveness of this method is demonstrated by finite element (FE) analyses and further verified with a prototype. The experimental results from the prototype recorded a 90% reduction in comparison to the traditional platforms in the wrapping deformation of the payload panel, which was measured by projection moiré methods. The thermal wrapping deformation decreased from 1.013 mm using the rigid connection to 0.104 mm using the flexible connection. This result proves that the proposed method is effective for a high-precision satellite structure and has considerable potential in engineering applications.
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