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Ho, Vu Ngoc Anh,Pham, Toan Duong,Nguyen, Nam Thanh,Hoang, Hieu Le Trung,Ho, Tuong Manh,Vuong, Lan Ngoc The Korean Society for Reproductive Medicine 2022 Clinical and Experimental Reproductive Medicine Vol.49 No.2
Objective: This study aimed to investigate the impact of hyperandrogenism (HA) on the outcomes of ovulation induction (OI) using gonadotropin and intrauterine insemination (IUI) in patients with polycystic ovary syndrome (PCOS). Methods: This was a retrospective cohort study including 415 patients undergoing OI using gonadotropin and IUI treatment between January 2018 and December 2020 at a single infertility center. Baseline characteristics, clinical and laboratory parameters, and pregnancy outcomes were investigated. Results: Among the study population, there were 105 hyperandrogenic (25.3%) and 310 non-hyperandrogenic patients (74.7%). The live birth rate was lower in the HA group than in the non-HA group, but this difference did not reach statistical significance due to the limited sample size (14.3% vs. 21.0%, relative risk=0.68; 95% CI, 0.41-1.14, p=0.153). No predictive factors for live birth were identified through logistic regression analysis. Conclusion: HA did not negatively affect the outcomes of OI using gonadotropin and IUI cycles in Vietnamese women with PCOS. The result may not be applicable elsewhere due to the large variation in the characteristics of women with PCOS across races and populations.
ĐÁNH GIÁ KHẢ NĂNG LÀM LÀNH VẾT BỎNG TRÊN CHUỘT CỦA HYDROGEL TỪ AgNP-CHITOSAN-CURCUMIN
Hoang Ngoc Anh Nhan,Nguyen Ba Trung,Giang Thi Kim Lien,Truong Thi My Phuong,Ho Kha Vinh Nhan,Pham Xuan Anh 한국베트남학회 2023 베트남연구 Vol.21 No.1
Skin burn is one of the major causes of morbidity and mortality in burn patients due to its susceptibility to infection. The disruption of the epidermal barrier, combined with the denaturation of proteins and lipids, provides a fertile environment that is rich in bacterial nutrients for microbial growth, making it significantly prone to infection. This study aimed to formulate a thermoresponsive hydrogel containing silver nanoparticles (300 ppm), oligo chitosan 2%, and curcumin (0.1%) in the polymer pluronic F127 matrix with a final concentration of 13% to effectively promote the healing of skin wounds. The prepared thermoresponsive hydrogel was investigated for its physical and chemical stability, gelation temperature, and chemical composition. In addition to in vitro antibacterial activity against Staphylococcus aureus found in burn infections, in vivo burn healing and antibacterial activities were also investigated and compared with those of a commercial product using burn-induced infected wounds in mice. The formulation showed antibacterial activity with effective values for wound healing properties, as shown in vivo and by histopathological studies. This study also demonstrates that the thermoresponsive hydrogel was successful as an antibacterial and burned wound-healing transdermal drug delivery system.
Back-stepping Approach for Rolling Motion Control of an Under-actuated Two-wheel Spherical Robot
Hoang Quoc Dong,Soon-Geul Lee,Soo Ho Woo,Tuan-Anh Le 제어로봇시스템학회 2020 제어로봇시스템학회 국제학술대회 논문집 Vol.2020 No.10
Spherical robots are the mobile robots with the locomoting by displacing its centre of gravity to generate torque and rotate itself. Therefore, the angle of the main body inside the robot determines the position and posture of the robot. There is only one contact point between the robot and the ground, and the inappropriate control strategy can generate the sizeable angular amplitude of the main body. As a result, the stable movement of the robot cannot be satisfied along with the appeared vibrations. This problem significantly impacts the tracking control quality and creates the clumsy gestures of the robot. In this research, an under-actuated dynamic model-based back-stepping control focusing on the rolling motion is developed and applied for a designed two-wheel spherical robot. With the provided closed-loop control law, both the precision and stability of the robot’s movement are guaranteed. The entire work’s efficiency is investigated by the experimental results.
Ecofriendly Fall webworms management tools
Hoang Nguyen Minh Anh,Yoo Hee Kim,Young Ho Koh 한국응용곤충학회 2023 한국응용곤충학회 학술대회논문집 Vol.2023 No.10
Recently, the occurrence of the fall webworm, one of the foreign invasive pests, is rapidly increasing due to the increase in average annual temperature due to global climate changes. In this study, we are presenting diverse eco-friendly technologies to control the fall webworm. (Grant No. PJ014845032023).
Hoang Vu Dao,Xuan Dinh To,Hoai Vu Anh Truong,Tri-Cuong Do,Cong Minh Ho,Tri Dung Dang,안경관 한국정밀공학회 2021 International Journal of Precision Engineering and Vol.8 No.4
Fuel cell hybrid electric construction equipment (FCHECE) is known as a promising solution to achieve the goal of energy saving and environment protection. Energy management strategy is a key technology of FCHECE, which splits the energy fl ow between power sources. This paper presents a novel optimal energy management strategy for a hybrid electric-powered hydraulic excavator system to enhance power performance, power sources lifespan, and fuel economy. As for the proposed powertrain configuration, fuel cell serves as a primary energy source, and supercapacitor and battery are considered as energy storages. The integration of supercapacitor and battery in fuel cell vehicle has advantages of improving power performance and storing the regenerative energy for future usage. An energy management strategy based on fuzzy logic control and a rule-based algorithm is proposed to effectively distribute the power between the three sources and reuse the regenerative energy. Furthermore, the parameters of the fuzzy logic system are optimized using the combination of a backtracking search algorithm which provides a good direction to the global optimal region and sequential dynamic programming as a local search method to fi ne-tune the optimal solution in order to reduce the hydrogen consumption and prolong the lifetime of the power sources. Simulation results show that the proposed energy management strategy enhances the vehicle performance, improves fuel economy of the FCHECE by 10.919%, increase battery and supercapacitor charge-sustaining capability as well as efficiency of the fuel cell system.
Hoang, Cong Thanh,Hong, Yeojin,Truong, Anh Duc,Lee, Janggeun,Lee, Kyungbaek,Hong, Yeong Ho PERGAMON 2017 DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY Vol. No.
<P><B>Abstract</B></P> <P>Interleukin (IL)-17B is a little known member of the IL-17 cytokine family, which plays an important role in immunity by regulating the expression of proinflammatory cytokines. In this study, we determined the coding sequence and biological functions of a novel chicken IL-17B (chIL-17B). The full-length chIL-17B coding sequence includes 567 nucleotides encoding 188 amino acids, which was identified in small intestinal epithelial cells. The chIL-17B protein shares 96.48% amino acid sequence identity with turkey, 92.57% with duck, and 44.92–64.06% with mammalian IL-17B proteins. ChIL-17B shares three exons and two introns with mammals, turkey, and duck. Moreover, IL-17B mRNA was more highly expressed than IL-17A mRNA in several organs of chickens infected with <I>Salmonella</I> and was upregulated in chicken cell lines following LPS stimulation. In addition, in chicken cell lines, chIL-17B induced the mRNA expression of several proinflammatory cytokines, including IL-1β, IL-6, LITAF, and INF-γ, but not IL-17A, and activated MyD88, TAK1, NF-κB1, and SOCS1, which are associated with the NF-κB signaling pathway. Taken together, chicken interleukin-17B plays a critical role in host defense against the bacterial pathogens, and regulates proinflammatory cytokines by activating the NF-κB signaling pathway.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A novel chicken interleukin-17B (chIL-17B) was cloned. </LI> <LI> Chicken IL-17B expression was upregulated in response to bacterial infection. </LI> <LI> Chicken IL-17B functions through the NF-κB signaling pathway. </LI> <LI> ChIL-17B overexpression activates proinflammatory cytokines in HD11, OU2, and CU91 cells. </LI> </UL> </P>