Ch'u Yu's "Chien-teng hsin-hua" : the literary tale in transition

Harmon, Coy Leon University Microfilms International 1985 국내박사

1950년대 중립국감시위원단에 대한 연구 : 미국의 대한군사정책을 중심으로

Harmon, Dan C 서울대학교 대학원 2003 국내석사

From the very conception of the Neutral Nations Supervisory Commission it played an integral part in shaping the role of the US military in Korea. After intense negotiations deciding the framework of the NNSC it became one of the solidifying factors of the Armistice Agreement. It was activated in July 1953 and designed to enforce article II of the Armistice Agreement in order to keep a balance of power on the Korean peninsula and therefore avoid any future hostilities. Opposition to the NNSC from both the US and South Korea began to arise shortly after its conception. From early 1954, both the US and South Korea began to make claims that the Communists were exploiting their participation in the NNSC and were violating terms of the Armistice by modernizing forces in North Korea. The US and South Korea believed that the North had succeeded in bringing in thousands of tanks, trucks, mortars, rifles, and military aircraft. It was also claimed that the Communists were utilizing inspection functions of the NNSC as a means to gather intelligence in South Korea. Allegations of espionage from the Inspection Teams in South Korea created widespread opposition and demonstrations in the country. These demonstrations brought about serious tension between the US and South Korea. Although the demonstrations were suspended in December 1955, the strong opposition of the NNSC by the South Korean government continued to have a strong impact on the US. The most serious problem was the fact that the US military in Korea was limited by the NNSC. The policies created by the New Look were not being implemented on the peninsula. Concerns associated with a reduction of the budget made it imperative that military modernization takes place. A modernized military would also allow the US to begin carrying out plans of US troop reductions as recommended in NSC series 156. However, the US believed that modernization on the peninsula could not take place until after abolishing the NNSC. The US wanted to put some highly sensitive new equipment in Korea, which they didn't want anyone to have the right to inspect. With these objectives in mind it was obvious that only the complete abolishment of the NNSC would satisfy the needs of the United States. The US felt the best way to handle the inadequacies of the NNSC and accomplish their own goals on the peninsula was to abolish the Commission. For approximately two years the US continued to pursue ways to complete this task without violating the Armistice Agreement. Finally, in May 1956, after exhausting all other options, the US informed the Military Armistice Commission that due to Communist non-compliance it was temporarily suspending the provisions of the Armistice Agreement governing the NNSC.

Molecular imaging biomarkers in prostate and lung cancers

Harmon, Stephanie A ProQuest Dissertations & Theses The University of 2016 해외박사(DDOD)

소속기관이 구독 중이 아닌 경우 오후 4시부터 익일 오전 9시까지 원문보기가 가능합니다.

There is a fundamental need for comprehensive patient characterization and treatment response assessment in clinical oncology. Molecular imaging allows for survey of functional and biological characteristics of a patient's disease throughout treatment. Traditional integration of imaging in clinical care has relied on qualitative evaluation. The overall objective of this dissertation was to evaluate the utility of quantitative molecular imaging in two oncologic malignancies, non-small cell lung cancer (NSCLC) and metastatic castration-resistant prostate cancer (mCRPC). In lung cancer, there is an urgent need to identify early-stage NSCLC patients at risk of post-surgical disease recurrence. We evaluated quantitative metrics from pre-surgical 18F-FDG PET/CT in early-stage NSCLC patients, correlating uptake patterns with outcome intervals. We found metrics describing uptake heterogeneity, including Entropy-GLCM, showed significant, independent associations with 5-year disease-free survival. We also reported significant differences in imaging metrics across squamous cell carcinoma (SCC) and adenocarcinoma (AC) histologies. Our work highlights this phenomenon influences population-level correlation to outcome, with enhanced characterization and predictive ability when accounting for histological differences. Typically characterized by qualitative assessment, i.e. counting of lesions, quantitative biomarkers of mCRPC are in their infancy. We investigated quantitative 18F-NaF PET/CT metrics by evaluating individual lesions throughout treatment for complete disease assessment. Total function burden (SUV total) of metastatic bone lesions determined by NaF PET/CT was the strongest correlate of progression-related events in a population of mCRPC patients. Response in SUVtotal assessed within 12 weeks of starting therapy could serve as a surrogate endpoint of progression-related events. mCRPC patients are largely evaluated on appearance of new or worsening lesions, our strong correlation to progression-related events indicates the bias of clinical decisions mediated by a small population of lesions could undersample patient benefit. Finally, we have outlined the development and testing of a novel algorithm to guide clinical biopsies for patients with multiple tumors. Typical workflow of clinical biopsies in these cases are based on physician discretion. By combining quantitative imaging information with physician feasibility requirements, robust biopsy site selection in was achieved. This novel algorithm can serve as a basis for automatic site selection in any case of patients with multiple lesions.

Living related donor islet transplantation in the haplotype identical chimeric rhesus macaque

Harmon, James Vail, Jr University of Minnesota 2012 해외박사(DDOD)

소속기관이 구독 중이 아닌 경우 오후 4시부터 익일 오전 9시까지 원문보기가 가능합니다.

Islet allograft transplantation has the potential to reverse type 1 diabetes if maintenance immunosuppression is provided indefinitely. The development of a protocol to achieve durable islet allograft function without the need for indefinite, immunosuppression remains a research goal of significant interest. This study describes a hematopoietic stem cell (HSC), nonhuman primate (NHP), preclinical, transplant protocol that takes steps toward reaching that goal. This protocol involves living donor hematopoietic stem cell transplantation followed by donor specific islet transplantation to reverse diabetes. A low intensity preconditioning regimen with low-dose total body irradiation (TBI) and cyclophosphamide was well tolerated. Antibody induction and temporary immunosuppression resulted in high levels of HSC engraftment confirmed by short tandem repeat (STR) DNA markers. The hematopoietic stem cell transplantation (HSCT) was completed on day 75. Recipient diabetes induction was performed on day 96. Donor specific islet transplantation without ongoing immunosuppression was performed on day 126. One chimeric recipient maintained islet allograft function for 92 days without ongoing immunosuppression. A recipient that failed to engraft donor stem cells lost islet allograft function at 14 days. The islet allograft failed immediately in a chimeric recipient documented to have developed donor specific antibodies. Durable allograft tolerance was not achieved in any recipient using this protocol. However HSCT protocols modified to achieve T-regulatory cell enrichment with could be evaluated using this preclinical model. This preclinical model could also be used to investigate the immunologic mechanisms involved in donor specific allograft tolerance.

Investigating mantle dynamics beneath young Pacific seafloor: Results from the GLIMPSE experiment

Harmon, Nicholas Brown University 2007 해외박사(DDOD)

소속기관이 구독 중이 아닌 경우 오후 4시부터 익일 오전 9시까지 원문보기가 가능합니다.

Plate tectonic theory and hotspot theory explain the presence of volcanism at plate boundaries and over mantle plumes such as Hawaii. However, there are linear intraplate volcanic ridges associated with free air gravity lineaments in the south central Pacific Ocean that are not explained by these two theories. The GLIMPSE experiment employed several geophysical techniques to explore the origin of two of these volcanic features: the Sojourn Ridge and the Hotu Matua Volcanic Complex. Using data from bathymetric surveying, gravimetric surveying, body wave delay analyses, shear wave splitting analyses, seismic impulse responses determined from ambient seismic noise, and surface wave tomography, I find overwhelming evidence that a dynamic mantle component is required to produce the observed bathymetric, gravimetric, and seismic anomalies associated with the intraplate volcanism and gravity lineations. I show that models of small-scale convection or channelized asthenospheric return flow are likely, while lithospheric boudinage models or thermoelastic cracking models cannot completely explain all of the observations.

Is that all there is? Gender, expectation, and abusiveness in adolescent romantic relationships

Harmon, Mary Patricia Harvard University 2006 해외박사(DDOD)

소속기관이 구독 중이 아닌 경우 오후 4시부터 익일 오전 9시까지 원문보기가 가능합니다.

This study used quantitative and qualitative methods to examine the influence of gender and trauma-associated emotional development on adolescent romantic relationship expectations and experiences, including dating violence and potential for abusiveness. The sample consists of 263 ninth-grade students from three socioeconomically and racially diverse public high schools. Twenty-three students were interviewed individually. This study tested and provided strong evidence for the applicability of an integrated feminist-trauma model to adolescent romantic relationships. A multidimensional approach was demonstrated for complex gender analyses, considering gender beliefs, socialized gender effects on the self, power-imbalanced relational dynamics, and intersections with trauma-associated emotional development. In addition to examining sex differences in emotional and relational outcomes, this study compared the relative strength of femininity and masculinity ideologies (Chu, Porche, & Tolman, 2005; Tolman & Porche, 2000), hostility and benevolence toward the other sex (Glick & Fiske, 1996, 1999), gender role stress (Gillespie & Eisler, 1992; Eisler & Skidmore, 1987), and gendered beliefs about emotion in predicting adolescent romantic relationship outcomes and propensity for abusiveness. Dissociation, shame-proneness, guilt, blaming orientation, alexithymia, violence exposure, and witnessing parental violence were measured. For girls, objectified view of own body and hostility toward men were consistently associated with negative relational outcomes and propensity for abusiveness. For boys, hostility toward women was associated with higher propensity for abusiveness and negative relational outcomes. Emotional development attenuated some effects of gender, providing evidence of a mediational role, and explained substantial variation in every model. Qualitative analyses demonstrated how adolescents' ideals of relational egalitarianism are undermined by gendered inequalities, which are observed among parents and peers, accepted as a natural order, and perpetuated through a privileging of male entitlement and devaluing of female emotion and perspective. An "Imperious Kingdom" characterized by Asymmetrical Accountability, Male Relational Disregard, Blatant Sexism, Crazy-Making, and Dissociative Compromises is described. In this context, boys' construction of counter-identities against images of "bad men" paradoxically shields boys from examination of their complicity in accepted practices that harm girls, while girls' losses of trust are attributed to individual psychopathology (by both boys and girls). Girls' practices of Confronting Relational Injustices are discussed.

Factors affecting the activation of predictive inferences

Harmon, Mary E University of New Hampshire 2005 해외박사(DDOD)

소속기관이 구독 중이 아닌 경우 오후 4시부터 익일 오전 9시까지 원문보기가 가능합니다.

Past research has demonstrated that predictive inferences are difficult to detect when distracting material is present (Klin, Guzaman, & Levine, 1999b). The experiments in this dissertation were designed to explore both how and why distracting material influences the availability of predictive inferences. Participants were presented with passages containing either a neutral introduction or a distractor introduction followed by an inference-evoking sentence or a control sentence. In Experiment 1, activation of predictive inferences was detected with a naming task, but not in the presence of distracting information. In Experiments 2 and 3, there was no evidence of activation of a "distractor" inference when using either a naming or reading task. In Experiment 4, there was evidence of activation of predictive inferences when the amount of distracting information was reduced, suggesting that elaboration of distracting material interferes with the ability to detect activation of predictive inferences. Finally, the results from Experiment 5 indicated that it is only related distracting information the interferes with activation of predictive inferences. The results are interpreted within the memory-based view of text processing and the resonance model.

Fundamental properties and applications of responsive hydrogels in confined geometries

Harmon, Marianne Elisabeth Stanford University 2003 해외박사(DDOD)

소속기관이 구독 중이 아닌 경우 오후 4시부터 익일 오전 9시까지 원문보기가 가능합니다.

Responsive hydrogels can undergo a dramatic change in volume in response to different stimuli, but applications of these materials inevitably constrain the swelling behavior in some way. Here we present a study of the fundamental properties of responsive hydrogels in confined geometries, focusing on applications of these materials. We have developed a technique based on surface plasmon resonance and optical waveguide spectroscopy to study temperature-responsive <italic> N</italic>-isopropylacrylamide (NIPAAm) hydrogel layers and the resulting anisotropic swelling as a function of temperature, pH, salt concentration, and hydrostatic pressure. We have used photocrosslinkable co- and terpolymers based on NIPAAm and 2-(dimethyl maleimido)-<italic>N</italic>-ethyl-acrylamide as the photosensitive component to prepare uniform hydrogel layers with dry film thicknesses ranging from approximately 10 nm to 2.5 μm. The volume phase transition is characterized by the degree of swelling and the transition temperature, and the variation of these parameters in response to different stimuli were explained by existing models for the anisotropic swelling of hydrogel layers. The hydrogel mechanical properties were measured with atomic force microscopy, and it was possible to study the gel morphology by comparing the measured modulus to that calculated from theory. We have also studied the effect of reference state by using free-radical polymerized hydrogel layers, and these materials were compared to the corresponding bulk hydrogels. Finally, we have evaluated the potential use of NIPAAm hydrogels as actuators in microfluidic devices, which requires that the hydrogel swelling be anisotropic. The kinetics of the volume phase transition is often a limiting factor, and we have studied the time scale of response for a series of semi-interpenetrating polymer networks (semi-IPNs) based on NIPAAm hydrogels. We have used confocal fluorescence microscopy to image the internal structures of the semi-IPNs, and the rate of response is interpreted as a function of the composition as well as the morphology of the samples. The performance and limitations of the hydrogel actuator were interpreted in terms of the kinetics of the volume phase transition as well as the degree of swelling and transition temperature of the hydrogel layers.

A sense of urgency: Transforming the literate identities of students who struggle with learning to read

Harmon, Melinda R University of Kentucky 2013 해외박사(DDOD)

소속기관이 구독 중이 아닌 경우 오후 4시부터 익일 오전 9시까지 원문보기가 가능합니다.

This Grounded Theory study explored the identity development of four current and two former Reading Recovery students. The study focused on the interactions between self-efficacy, self-regulation and identity as students participated in the Reading Recovery intervention to capture change over time in the identity development of students who initially struggled with learning to read. The research questions for this study were: (a)What perceptions are held by emergent readers as they enter the Reading Recovery intervention? (b) How are Reading Recovery students perceived by others (teachers, parents) as they enter Reading Recovery? (c)How do these initial perceptions change across time? (d) How do these shifting perceptions contribute to the development of a literate identity across time?. While students did not always see themselves as struggling readers, findings indicated that both the classroom and intervention teachers saw students as struggling readers as they began the intervention. Differences became apparent in the instructional practices as the classroom teacher focused on low-level skills instruction and used ability grouping. The Reading Recovery teacher supported the development of a problem solving system. The instructional interactions focused on strategy use, control and persistence supported improvements in self-regulation, self-efficacy and identity. A recommendation for practice includes providing professional development to teachers on the connections between literacy learning and identity. Students' perceptions of themselves as literacy learners are of critical importance especially when learning to read. This leads to a recommendation for future research. We need additional research focusing teachers on how the use of ability groupings can influence student's identities as readers and ultimately as learners. Additionally, research that includes identity development framed around learning could support teachers' work with students. Perhaps by focusing teachers' attention to their own learning and evolving identities would support their understanding of learning and identity processes thus supporting their work with children. The ultimate message should be; we change who we are as we learn. KEYWORDS: Struggling Readers/Identity/Self-Regulation/Self-Efficacy/ Reading Recovery.

Robust, efficient, and accurate contact algorithms

Harmon, David Columbia University 2010 해외박사(DDOD)

소속기관이 구독 중이 아닌 경우 오후 4시부터 익일 오전 9시까지 원문보기가 가능합니다.

Robust, efficient, and accurate contact response remains a challenging problem in the simulation of deformable materials. Contact models should robustly handle contact between geometry by preventing interpenetrations. This should be accomplished while respecting natural laws in order to maintain physical correctness. We simultaneously desire to achieve these criteria as efficiently as possible to minimize simulation runtimes. Many methods exist that partially achieve these properties, but none yet fully attain all three. This thesis investigates existing methodologies with respect to these attributes, and proposes a novel algorithm for the simulation of deformable materials that demonstrate them all. This new method is analyzed and optimized, paving the way for future work in this simplified but powerful manner of simulation.