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Kazuhiko Goto,Takenao Sugi,Yoshitaka Matsuda,Satoru Goto,Hiroki Fukuda,Yoshinobu Goto,Takao Yamasaki,Shozo Tobimatsu 제어로봇시스템학회 2013 제어로봇시스템학회 국제학술대회 논문집 Vol.2013 No.10
Visual evoked potentials (VEPs) are the electrical responses from the brain concerned with visual information processing. Amplitude of VEPs is smaller than that of background EEG activity, and the stimulus-locked averaging method is usually used for obtained the waveform. VEP response to each stimulus is not completely the same however it is varying with its amplitude and duration. Therefore, amplitude of averaged VEP waveform deteriorates due to their variability in raw data. Feature extraction of background EEG activity during visual stimulation is also a one of significant items in VEP analysis. In that case, separation of VEP component and background EEG component (mainly posterior dominant rhythm) is crucial. In the past, we proposed the method of estimating both amplitude of VEP and dominant rhythm by use of EEG model. This present study, the proposed method was applied to actual recorded VEP data and its effectiveness was evaluated. EEGs with visual stimulus were recorded from nine healthy young adults. Usefulness of the proposed method was investigated by comparing the conventional power spectrum averaging method. The proposed method will be applicable to show an accurate VEP analysis and characteristic analysis of background activity under visual stimulus.
No Association between the CDX2 G543C Polymorphism and Risk of Gastric Atrophy and Cancer
Goto, Yasuyuki,Kato, Tsuyoshi,Ando, Takafumi,Goto, Hidemi,Hamajima, Nobuyuki Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.11
Ectopic expression of CDX2 in the stomach is closely associated with chronic Helicobacter pylori (H. pylori) infection and intestinal metaplasia. Whether CDX2 has tumor suppression or tumorigenesis potential remains to be elucidated. In this study, we investigated the association between the CDX2 G543C polymorphism (silent mutation) and the risk for H. pylori-induced gastric atrophy and cancer as well as H. pylori infection, using 454 Japanese subjects undergoing a health checkup and 202 gastric cancer patients. The frequency of the minor allele was the same as previously reported in China, but different from that reported in England. CDX2 G543C was not associated with risk of H. pylori infection, gastric atrophy, or gastric cancer, although the point estimate for non-cardiac differentiated gastric cancer as compared to controls with gastric atrophy was 2.22 (95%CI=0.17-29.4). In conclusion, our results indicate that the CDX2 G543C polymorphism is unlikely to affect the H. pylori infection-gastric atrophy-gastric cancer sequence.
The leading ideal of a complete intersection of height two, Part II
Goto, Shiro,Heinzer, William,Kim, Mee-Kyoung Elsevier 2007 Journal of algebra Vol.312 No.2
<P><B>Abstract</B></P><P>Let (S,n) be a regular local ring and let I=(f,g) be an ideal in <I>S</I> generated by a regular sequence f,g of length two. Let R=S/I and m=n/I. As in [S. Goto, W. Heinzer, M.-K. Kim, The leading ideal of a complete intersection of height two, J. Algebra 298 (2006) 238–247], we examine the leading form ideal <SUP>I∗</SUP> of <I>I</I> in the associated graded ring G=<SUB>grn</SUB>(S). If <SUB>grm</SUB>(R) is Cohen–Macaulay, we describe precisely the Hilbert series H(<SUB>grm</SUB>(R),λ) in terms of the degrees of homogeneous generators of <SUP>I∗</SUP> and of their successive GCD's. If D=GCD(<SUP>f∗</SUP>,<SUP>g∗</SUP>) is a prime element of <SUB>grn</SUB>(S) that is regular on <SUB>grn</SUB>(S)/(<SUP>f∗</SUP>D,<SUP>g∗</SUP>D), we prove that <SUP>I∗</SUP> is 3-generated and a perfect ideal. If <SUB>ht<SUB>grn</SUB>(S)</SUB>(<SUP>f∗</SUP>,<SUP>g∗</SUP>,<SUP>h∗</SUP>)=2, where h∈I is such that <SUP>h∗</SUP> is of minimal degree in <SUP>I∗</SUP>∖(<SUP>f∗</SUP>,<SUP>g∗</SUP>)<SUB>grn</SUB>(S), we prove <SUP>I∗</SUP> is 3-generated and a perfect ideal of <SUB>grn</SUB>(S), so <SUB>grm</SUB>(R)=<SUB>grn</SUB>(S)/<SUP>I∗</SUP> is a Cohen–Macaulay ring. We give several examples to illustrate our theorems.</P>
Quantitative analysis between visual mismatch negativity and psychopathology scale for schizophrenia
Kazuhiko Goto,Takenao Sugi,Toshihiko Maekawa,Katuya Ogata,Yoshinobu Goto,Shozo Tobimatsu,Masatoshi Nakamura 제어로봇시스템학회 2009 제어로봇시스템학회 국제학술대회 논문집 Vol.2009 No.8
Visual mismatch negativity (v-MMN) in electroencephalographic (EEG) record provides an index of preattentive information processing of the brain v-MMN is considered to reflect schizophrenia. The positive and negative syndrome scale (PANSS) is usually used in clinical diagnosis on patients with schizophyenia for estimating the degree of disorder. In this study, the relationship between v-MMN and PANSS was analyzed. Characteristic parameters of peals including N1, N2, P300, and MMN were established respectively. Estimated function was constructed by selected parameters. P300 was most significant characteristic related to all items of FANSS.
Goto, M.,Han, S.Z.,Euh, K.,Kang, J.H.,Kim, S.S.,Kawagoishi, N. Elsevier Science 2010 Acta materialia Vol.58 No.19
Fatigue tests were conducted on smooth specimens of ultrafine-grained copper produced by 4 and 12 passes of equal channel angular pressing (henceforth referred to as UFG4 and UFG12, respectively). A major crack was initiated from shear bands at an early stage of stressing. The UFG4 and UFG12 samples exhibited different growth behavior tendencies at a low crack growth rate (CGR). For UFG12, the CGR initially increased as the crack was extended with continued fatigue cycling, but then abruptly decreased before CGR reaching 10<SUP>-6</SUP>mm/c. This drop was temporary and was gradually recovered with subsequent cycling. The drop and recovery in CGR corresponded to the transitions from planar to granular fracture surface and from granular to striated fracture surface, respectively. For UFG4, there was no temporary CGR reduction, which corresponded to the change in the fracture surfaces from a planar to striated surface without any granulated surface formation. To understand the changes in growth rate and fracture surface morphologies, a quantitative model describing the crack growth mechanism is developed in this study by considering the reversible plastic zone size and the microstructural factors. The relationship between the crack growth behavior and the formation of the fracture surface is discussed based on the model.
Goto, M.,Yamamoto, T.,Han, S.Z.,Lim, S.H.,Kim, S.,Iwamura, T.,Kitamura, J.,Ahn, J.-H.,Yakushiji, T.,Lee, J. Elsevier 2019 Materials science & engineering. properties, micro Vol.747 No.-
<P><B>Abstract</B></P> <P>The effect of microstructure on the fatigue strength of age-hardened Cu–6Ni–1.5Si alloy was investigated in this study. The aging was conducted at 500 °C for 0.5 h for the precipitation of disk-shaped δ-Ni<SUB>2</SUB>Si precipitates (continuous precipitates) and 3 h for the discontinuous precipitation of fiber-shaped, stable δ-Ni<SUB>2</SUB>Si precipitates to strengthen the Cu matrix. The tensile strength of 0.5 h-aged specimens was about 1.3 times greater than that of the 3 h-aged counterparts, but with inferior electrical conductivity. Despite the considerable difference in tensile strength, no notable difference in fatigue strength was observed between 0.5 h- and 3 h-aged specimens. The 3 h-aged specimens had superior electrical conductivity without sacrificing fatigue strength of the 0.5 h-aged specimens. The physical background of high-cycle fatigue strength in Cu–6Ni–1.5Si alloys with continuous precipitates and discontinuous precipitates is discussed considering the microstructure-sensitive behavior of fatigue cracks.</P>
Goto, Masahiro,Teshima, N.,Han, Seung Zeon,Yakushiji, T.,Kim, Sang Shik Trans Tech Publications, Ltd. 2008 Materials science forum Vol.584 No.-
<P>In order to study the effect of trace impurities on high-cycle fatigue damage of ultrafine grained (UFG) copper, fatigue tests were carried out for two samples: oxygen-free copper (OFC, 99.99 wt% Cu) and deoxidized low-phosphorous copper (DLP, 99.95 wt% Cu). After the processing by equal channel angular pressing (ECAP) using eight passes, equiaxed grains with an average size of 250 nm were formed for both the samples. Fatigue strength of UFG copper was enhanced by the impurities. The formation behavior of surface damage and the change in surface hardness was monitored. A close relationship was observed between the change in hardness and the formation behavior of surface damage. The physical background of the effect of trace impurities on the fatigue damage was discussed from the viewpoints of surface damage formation behavior.</P>