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The Use of Cryotherapy in the Gout Pain Control: A Systematic Review
Alana Ludemila de Freitas Tavares,Iranilda Moha Ross,Lilian Araujo Pradal,Morgana Neves,Bárbara Heloise Trombetta Jamilk,Gladson Ricardo Flor Bertolini KEMA학회 2021 근골격계과학기술학회 Vol.5 No.1
Background Gout traditional treatment consists of anti-inflammatory drugs, analgesics and other rheumatic controllers, however, the occurrence of drug interactions occurs with a certain degree of toxicity, requiring that other methods be used to relieve symptoms. An alternative treatment is cryotherapy due to its capacity for analgesia. Purpose The aim of this study was to conduct a systematic review that addressed the literature with production on gouty arthritis and its treatment with cryotherapy. Study design Systematic review Methods This review was described according to the items requested by the PRISMA system. This is a systematic review of publications from the year 2000 to the year 2019 in the following white literature databases PubMed, LILACS, SciELO, Web of Science, Science Direct, Scopus, Cochrane, PEDro and in the gray literature a Google Scholar database. The electronic databases were consulted from November 2019. Results After searching the databases, reading and selection, two studies contemplated the methodological criteria of eligibility, being of the same authorship, both with more than ten years of publication, using similar methods of application of ice. Conclusions It was found that, despite the scarcity of studies that addressed the topic, the articles found show reasonable rigor methodological and homogeneous results, demonstrating that cryotherapy helps in reducing the pain of individuals with gout, however, there is little evidence to support this hypothesis.
André Junior Santana,Jean Carlos Debastiani,Regina Inês Kunz,Pamela Buratti,Rose Meire Costa Brancalhão,Lucinéia de Fátima Chasko Ribeiro,Márcia Miranda Torrejais,Gladson Ricardo Flor Bertolini 한국운동재활학회 2018 JER Vol.14 No.1
Physical exercise may help maintain muscle properties and functional improvement after peripheral nerve lesion, which may be enhanced by using biocompatible substances, such as sericin. The aim of this study was analyse the effect of sericin associated with swimming exercise on the phenotype, innervation, and functionality of the plantar muscle of Wistar rats. Forty randomly divided adult rats were used in five groups of eight animals: control, injury, sericin, exercise, exercise and sericin. The application of sericin was done on the spot, 100 μL, shortly after nerve compression. Three days after sciatic nerve compression, the swimming and swimming and sericin groups were submitted to physical swimming exercise for 21 days. Afterwards, the animals were euthanised and the plantar muscle was dissected and submitted to histochemical and histoenzymological techniques. The grip strength test did not show alterations in muscular functionality, and the control presented greater muscle mass in relation to the other groups, the same did not occur for muscle length. Polymorphic neuromuscular junctions were detected in the groups, although without significant morphometric alterations of the area, major and minor diameters. The percentage of type I fibres was lower in the lesion group and there was no difference in fibres IIa and IIb between groups. The area of fibres I, IIa and IIb remained constant between groups. Sericin biopolymer combined with swimming exercise did not affect plantar muscle function, submitted to experimental axonotmosis, whose contractile properties were altered by nerve injury.