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Giant Parathyroid Adenomas: Differential Aspects Compared to Atypical Parathyroid Adenomas
McCoy Kristin,Bakkila Baylee,Gibson Courtney 대한내분비외과학회 2022 The Koreran journal of Endocrine Surgery Vol.22 No.3
Primary hyperparathyroidism is a common diagnosis, often caused by a parathyroid adenoma, which can be resolved with surgical excision. However, pre-operative diagnosis of the causative adenoma may be challenging given the overlapping presentations and laboratory findings in typical, giant, and atypical parathyroid adenomas. In this case series, we describe one of the largest giant parathyroid adenomas excised in the United States and compare its presentation to that of an atypical parathyroid adenoma. Using this comparison, we aim elucidate the diagnostic value of various presentation characteristics, such as adenoma size, mass effect, symptom burden, and biochemical derangements.
Benign Recurrent Primary Hyperparathyroidism After Parathyroid Carcinoma
Jeoffrey Syeda Manahil Haider,McCoy Kristin L.,Gibson Courtney E. 대한내분비외과학회 2022 The Koreran journal of Endocrine Surgery Vol.22 No.4
This report describes the rare occurrence of a parathyroid adenoma 15 years after the resection of a right-sided parathyroid carcinoma, with recurrence of clinical manifestations of hyperparathyroidism. We report the case of a 41-year-old female who returned to the clinic with bone pain, memory difficulties and fatigue. After a thorough assessment, a hyperechoic nodule of parathyroid origin was detected and resected. The resected lesion was located inferior to the left thyroid lobe, measuring 1.3×0.7×0.6 cm and weighing 602 mg; histopathology was consistent with a parathyroid adenoma. Recurrent primary hyperparathyroidism due to benign adenoma, after prior surgery for parathyroid carcinoma, is a rare phenomenon. Early recognition, diagnosis and intervention are essential to prevent and/or reduce associated morbidity and mortality.