http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Gargi Ghoshal (검색결과 1 건)
- 무료
- 기관 내 무료
- 유료
-
Deepika Thakur,Ashay Jain,Gargi Ghoshal,U. S. Shivhare,O. P. Katare 한국약제학회 2017 Journal of Pharmaceutical Investigation Vol.47 No.5
Anthocyanin has been proven to impart several health benefits and biological functions. Though, various analytical methods have been reported for single/multicomponent analysis of anthocyanins, found to be tedious, time consuming and difficult to reproduce. Analytical studies on specific anthocyanins for estimation using an approach of Analytical Quality by Design are scarce. USP method is only reliable for cyanidin-3-O-glucoside (CY-3- O-Glu) estimation, but exploring many disadvantage of having high buffer concentration in mobile phase system and gradient elution, hence column blockage. So there is need to develop a novel HPLC method to overcome this problem with the use organic solvents with lesser volume of buffer in isocratic mode of elution. The aim is to develop a robust and precise method for estimation of CY-3-O-Glu in biopolymer based microcapsules and tablets. The optimized method consisted of mobile phase containing solvent A and B, flow rate 0.8 mL/min with 20 min of analysis time. The method was further validated in accordance with current ICH guidelines Q2 (R1) and found to be highly selective for component in the presence of degradation products confirmed by Mass spectra. Therefore, the proposed method was found to be suitable for routine analysis of CY-3-O-Glu in food and pharmaceutical based formulations.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
