Association between Parkinson’s Disease and Helicobacter Pylori

Gülşah C¸amcıa,Sıdıka Oğuzb 대한신경과학회 2016 Journal of Clinical Neurology Vol.12 No.2

Helicobacter pylori (HP) is a common infection of the gastrointestinal system that is usually related to peptic ulcers. However, recent studies have revealed relationships between HP and many other diseases. Although the exact mechanism is unknown, HP can prevent the absorption of certain drugs. A high prevalence of HP has been found in patients with Parkinson’s disease, and this bacterium causes motor fluctuations by affecting the absorption of levodopa, which is the main drug used to treat Parkinson’s disease. Eradicating HP from patients with Parkinson’s disease by applying antibiotic treatment will increase the absorption of levodopa and decrease their motor fluctuations.

Thermal Characteristics, Mechanical and Comfort Properties of Heat-Protective Textiles

Gülşah Pamuk,Berna Cüreklibatır Encan,Esra Zeynep Yıldız 한국섬유공학회 2023 Fibers and polymers Vol.24 No.12

Specially developed protective textiles are the greatest armor for people who are exposed to high heat or struggle against flames in their working environment. When the protective clothing worn is constantly exposed to these conditions, changes in their performance can be observed over time. Therefore, in this article, the effects of wetting on breaking, tearing, and seam strength are comparatively examined. A total of five fabrics used in the study were chosen from among the inherently heat-protective blends that are widely used commercially. Extensive research was conducted by combining different techniques such as differential scanning calorimeter and thermogravimetric analysis to characterize their thermal behavior. People working in high temperatures or firefighting often exhibit intense physical activity while performing their jobs, and the comfort of the protective clothing worn becomes even more important due to the adverse conditions of the environment they are in. For this reason, as a part of the study, parameters affecting thermo-physiological comfort such as air permeability, water vapor permeability, and thermal resistance were discussed for heat-protective fabrics selected within the scope of the work. Also, these comfort parameters are examined in terms of variables such as fabric weight, fabric structure, and fiber blend ratio. Based on the results of the study, it appears that the fabrics used are suitable for workwear at temperatures up to about 300 degrees. It is recommended that woven fabrics be chosen when strength is the primary concern, while knitted fabrics are ideal when comfort is the priority.

Effect of glide path preparation with PathFile and ProGlider on the cyclic fatigue resistance of WaveOne nickel-titanium files

Gülşah Uslu,Uğur İnan 대한치과보존학회 2019 Restorative Dentistry & Endodontics Vol.44 No.2

Objectives: The aim of this study was to investigate the effect of glide path preparation with PathFile and ProGlider nickel-titanium (NiTi) files on the cyclic fatigue resistance of WaveOne NiTi files. Materials and Methods: Forty-four WaveOne Primary files were used and divided into four groups (n = 11). In the first group (0 WaveOne), the WaveOne Primary files served as a control group and were not used on acrylic blocks. In the 1 WaveOne Group, acrylic blocks were prepared using only WaveOne Primary files, and in the PF+WaveOne group and PG+WaveOne groups, acrylic blocks were first prepared with PathFile or ProGlider NiTi files, respectively, followed by the use of WaveOne Primary files. All the WaveOne Primary files were then subjected to cyclic fatigue testing. The number of cycles to failure was calculated and the data were statistically analyzed using one-way analysis of variance (ANOVA) and the Tukey honest significant difference multiple-comparison test at a 5% significance level. Results: The highest number of cycles to failure was found in the control group, and the lowest numbers were found in the 1 WaveOne group and the PF+WaveOne group. Significant differences were found among the 1 WaveOne, PF+WaveOne, and control groups (p < 0.05). No statistically significant differences were found between the PG+WaveOne group and the other three groups (p > 0.05). Conclusion: Glide path preparation with NiTi rotary files did not affect the cyclic fatigue resistance of WaveOne Primary files used on acrylic blocks.

In vitro comparison of the cyclic fatigue resistance of HyFlex EDM, One G, and ProGlider nickel titanium glide path instruments in single and double curvature canals

Koray Yılmaz,Gülşah Uslu,Taha Özyürek 대한치과보존학회 2017 Restorative Dentistry & Endodontics Vol.42 No.4

Objectives: It was aimed to compare the cyclic fatigue resistances of ProGlider (PG), One G (OG), and HyFlex EDM (HEDM) nickel titanium glide path files in single- and double-curved artificial canals. Materials and Methods: 40 PG (16/0.02), 40 OG (14/0.03), and 40 HEDM (10/0.05) single-file glide path files were used in the present study. Sixty files were subjected to cyclic fatigue test by using double-curved canals and 60 files by using single-curved canal (n = 20). The number of cycles to fracture (NCF) was calculated and the length of the fractured fragment (FL) was determined by a digital micro-caliper. Twelve pieces of fractured files were examined with scanning electron microscope to determine fracture types of the files (n = 2). The NCF and the FL data were analyzed using one-way analysis of variance and post hoc Tukey test using SPSS 21 software (p < 0.05). Results: In all of the groups, NCF values were significantly lower in double-curved canals when compared to single-curved canals (p < 0.05). For both of single- and double-curved canals, NCF values of HEDM group in apical and coronal curvatures were found to be significantly higher than NCF values of PG and OG groups (p < 0.05). In both of single- and double-curved canals, NCF value of PG group was found significantly higher than OG group (p < 0.05). Conclusions: Within the limitations of this study, HEDM glide path files were found to have the highest cyclic fatigue resistance in both of single- and double-curved canals.

Lupus nephritis presenting with massive ascites and pleural effusion (pseudo-pseudo Meigs’ syndrome)

( Rabia Deniz ),( Gülşah Hacımurtazaoğlu-demir ),( Bilgin Karaalioğlu ),( Duygu Sevinç Özgür ),( Gamze Akkuzu ),( Fatih Yıldırım ),( Cemal Bes ) 대한류마티스학회 2024 대한류마티스학회지 Vol.31 No.2

The triad of ascites, pleural effusion, and elevated cancer antigen-125 (CA-125) levels in the absence of ovarian malignancy in systemic lupus erythematosus patients is specifically named pseudo-pseudo Meigs’ syndrome (PPMS) or Tjalma syndrome. In this case we reported a 33 years female patient with pleural effusion lasting for 3 years and new onset progressive massive ascites and increased level of CA-125. After she was evaluated for an underlying benign and malign ovarian tumor or any other malignancies, serologic tests were requested with respect to progressive renal dysfunction, proteinuria, lymphopenia, anemia, and effusion. She was diagnosed with systemic lupus erythamatosus (SLE) and renal biopsy showed class-V lupus nephritis. Immunosuppressive treatment led to improvement in both SLE activity and components of PPMS, including massive ascites and pleural effusion and without the need of diuretics. Co-existence of unexplained CA-125 increase, pleural effusion, and ascites might be related to PPMS and detailed examination to exclude malignancy and early and effective treatment of SLE are the mainstay of management.

The effects of autoclave sterilization on the cyclic fatigue resistance of ProTaper Universal, ProTaper Next, and ProTaper Gold nickel-titanium instruments

Taha Özyürek,Koray Yılmaz,Gülşah Uslu 대한치과보존학회 2017 Restorative Dentistry & Endodontics Vol.42 No.4

Objectives: It was aimed to compare the cyclic fatigue resistances of ProTaper Universal (PTU), ProTaper Next (PTN), and ProTaper Gold (PTG) and the effects of sterilization by autoclave on the cyclic fatigue life of nickel-titanium (NiTi) instruments. Materials and Methods: Eighty PTU, 80 PTN, and 80 PTG were included to the present study. Files were tested in a simulated canal. Each brand of the NiTi files were divided into 4 subgroups: group 1, as received condition; group 2, pre-sterilized instruments exposed to 10 times sterilization by autoclave; group 3, instruments tested were sterilized after being exposed to 25%, 50%, and 75% of the mean cycles to failure, then cycled fatigue test was performed; group 4, instruments exposed to the same experiment with group 3 without sterilization. The number of cycles to failure (NCF) was calculated. The data was statistically analyzed by using one-way analysis of variance and post hoc Tukey tests. Results: PTG showed significantly higher NCF than PTU and PTN in group 1 (p < 0.05). Sterilization significantly increased the NCF of PTN and PTG (p < 0.05) in group 2. PTN in group 3 had significantly higher cyclic fatigue resistance than PTN group 4 (p < 0.05). Also, significantly higher NCF was observed for PTG in group 2 than in groups 3 and 4 (p < 0.05). Conclusions: PTG instrument made of new gold alloy was more resistant to fatigue failure than PTN and PTU. Autoclaving increased the cyclic fatigue resistances of PTN and PTG.

The effect of root canal preparation on the surface roughness of WaveOne and WaveOne Gold files: atomic force microscopy study

Taha Özyürek,Koray Yılmaz,Gülşah Uslu,Gianluca Plotino 대한치과보존학회 2018 Restorative Dentistry & Endodontics Vol.43 No.1

Objectives To examine the surface topography of intact WaveOne (WO; Dentsply Sirona Endodontics) and WaveOne Gold (WOG; Dentsply Sirona Endodontics) nickel-titanium rotary files and to evaluate the presence of alterations to the surface topography after root canal preparations of severely curved root canals in molar teeth. Materials and Methods Forty-eight severely curved canals of extracted molar teeth were divided into 2 groups (n = 24/each group). In group 1, the canals were prepared using WO and in group 2, the canals were prepared using WOG files. After the preparation of 3 root canals, instruments were subjected to atomic force microscopy analysis. Average roughness and root mean square values were chosen to investigate the surface features of endodontic files. The data was analyzed using one-way analysis of variance and post hoc Tamhane's tests at 5% significant level. Results The surface roughness values of WO and WOG files significantly changed after use in root canals (p < 0.05). The used WOG files exhibited higher surface roughness change when compared with the used WO files (p < 0.05). Conclusions Using WO and WOG Primary files in 3 root canals affected the surface topography of the files. After being used in root canals, the WOG files showed a higher level of surface porosity value than the WO files.

Incidence of apical crack formation and propagation during removal of root canal filling materials with different engine driven nickel-titanium instruments

Taha Özyürek,Vildan Tek,Koray Yılmaz,Gülşah Uslu 대한치과보존학회 2017 Restorative Dentistry & Endodontics Vol.42 No.4

Objectives: To determine the incidence of crack formation and propagation in apical root dentin after retreatment procedures performed using ProTaper Universal Retreatment (PTR), Mtwo-R, ProTaper Next (PTN), and Twisted File Adaptive (TFA) systems. Materials and Methods: The study consisted of 120 extracted mandibular premolars. One millimeter from the apex of each tooth was ground perpendicular to the long axis of the tooth, and the apical surface was polished. Twenty teeth served as the negative control group. One hundred teeth were prepared, obturated, and then divided into 5 retreatment groups. The retreatment procedures were performed using the following files: PTR, Mtwo-R, PTN, TFA, and hand files. After filling material removal, apical enlargement was done using apical size 0.50 mm ProTaper Universal (PTU), Mtwo, PTN, TFA, and hand files. Digital images of the apical root surfaces were recorded before preparation, after preparation, after obturation, after filling removal, and after apical enlargement using a stereomicroscope. The images were then inspected for the presence of new apical cracks and crack propagation. Data were analyzed with χ2 tests using SPSS 21.0 software. Results: New cracks and crack propagation occurred in all the experimental groups during the retreatment process. Nickel-titanium rotary file systems caused significantly more apical crack formation and propagation than the hand files. The PTU system caused significantly more apical cracks than the other groups after the apical enlargement stage. Conclusions: This study showed that retreatment procedures and apical enlargement after the use of retreatment files can cause crack formation and propagation in apical dentin.

Effect of adaptive motion on cyclic fatigue resistance of a nickel titanium instrument designed for retreatment

Taha Özyürek,Koray Yılmaz and Gülşah Uslu 대한치과보존학회 2017 Restorative Dentistry & Endodontics Vol.42 No.1

Objectives: The aim of this study was to evaluate the cyclic fatigue resistance of the ProTaper Universal D1 file (Dentsply Maillefer) under continuous and adaptive motion. Materials and Methods: Forty ProTaper Universal D1 files were included in this study. The cyclic fatigue tests were performed using a dynamic cyclic fatigue testing device, which had an artificial stainless steel canal with a 60° angle of curvature and a 5 mm radius of curvature. The files were randomly divided into two groups (Group 1, Rotary motion; Group 2, Adaptive motion). The time to failure of the files were recorded in seconds. The number of cycles to failure (NCF) was calculated for each group. The data were statistically analyzed using Student’s t-test. The statistical significant level was set at p < 0.05. Results: The cyclic fatigue resistance of the adaptive motion group was significantly higher than the rotary motion group (p < 0.05). Conclusion: Within the limitations of the present study, the ‘Adaptive motion’ significantly increased the resistance of the ProTaper Universal D1 file to cyclic facture.

HOMOTHETIC MOTIONS WITH GENERALIZED TRICOMPLEX NUMBERS

( Siddika Özkaldi Karakuş ),( Ferdağ Kahraman Aksoyak ),( Gülşah Özaydin ) 호남수학회 2024 호남수학학술지 Vol.46 No.1

In this paper, we define the generalized tricomplex numbers and give some algebraic properties of them. By using the matrix representation of generalized tricomplex numbers, we determine a motion on the hypersurface M in eight dimensional generalized linear space ℝ⁸_α_βγ and show that this is a homothetic motion. Also, for some special cases of the real numbers α, β and γ, we give some examples of homothetic motions in ℝ⁸ and ℝ⁸₄ and obtain some rotational matrices in these spaces, too.