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RISS 인기검색어
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- 저자 : Foong Koon Cheah (검색결과 2 건)
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CT and MRI Cardiac Imaging in Singapore: A Historical Context
Foong Koon Cheah 아시아심장혈관영상의학회 2021 Cardiovascular Imaging Asia Vol.5 No.3
In Singapore, the development and progression of cardiac imaging mirrors that in many other parts of the world. The interventional radiologists of the 1970s and 1980s could perform coronary angiography but the rise of cardiologists with the requisite clinical and technical skills meant radiologists were gradually concentrating their skills in the non-cardiac arena.
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Prognostic Value of Coronary Artery Calcium in a Multi-Ethnic Asian Cohort
Shu Yun Heng,Jien Sze Ho,Seyed Ehsan Saffari,Zijuan Huang,Foong Koon Cheah,Siang Jin Terrance Chua,Yung Jih Felix Keng,Lohendran Baskaran,Swee Yaw Tan 아시아심장혈관영상의학회 2021 Cardiovascular Imaging Asia Vol.5 No.3
Objective: Coronary artery calcium (CAC) is associated with the presence of coronary atherosclerotic plaque and is a prognostic factor of cardiovascular events. CAC varies among ethnic groups in patients of the same age and gender. Studies on the prognostic value of CAC in a multi-ethnic Asian population have yet to be performed. We aim to study the association of CAC and ethnicity, all-cause mortality, and acute myocardial infarction (AMI). Materials and Methods: This is a retrospective study with a multi-ethnic cohort aged 35–84 years from a single tertiary institution between 2007–2017. The individuals were all clinically referred for cardiac CT calcium scanning. CAC was determined by Toshiba Aquilion One 320 Multi-detector Row CT (Toshiba Medical System). Results: This study had 65% males at an average age of 55 years. In our multivariable analysis of 16561 individuals, CAC is generally higher in the Malay than Chinese ethnic group [odds ratio (OR)=1.30, 95% confidence interval (CI)=1.10–1.55] and did not differ among Indians and Chinese (p=0.400). Increasing CAC was associated with higher all-cause mortality (OR=1.27, 95% CI=1.17–1.36) and AMI (OR=1.50, 95% CI=1.35–1.66) after adjusting for known cardiovascular risk factors. Incorporation of CAC into a model with known cardiovascular risk variables enhanced prediction of all-cause mortality [area under the curve (AUC)=0.78] and AMI (AUC=0.85). Conclusion: This study is the largest performed in a multi-ethnic Asian cohort. Malay ethnicity seems to confer a higher likelihood of coronary calcification compared to the Chinese and Indians. CAC was associated with higher all-cause mortality and AMI and complemented traditional cardiovascular risk factors in risk prediction, confirming its applicability in a multi-ethnic Asian population.
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