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      • KCI등재

        Plagiarism detection in manuscripts submitted to the Journal of Surgical Sciences between 2020 and 2021: a case study

        Florentina Mușat,Dan Nicolae Păduraru,Alexandra Bolocan,Daniel Ion,Alexandru Constantinescu,Octavian Andronic 한국과학학술지편집인협의회 2023 Science Editing Vol.10 No.2

        The aim of this study was to share our experience with plagiarism detection in manuscripts submitted to the Journal of Surgical Sciences, a Romania-based medical journal, between 2020and 2021. We analyzed similarity score reports from 200 articles submitted consecutively forpublication between 2020 and 2021 generated by PlagScan, a software tool for plagiarism de-tection. The similarity score ranged from 0% to 92.4%, and 45 articles presented scores over 25.0%. According to PlagScan’s results, more than half of the submitted articles had a similarity score of more than 10% and one-third of them had a similarity score above 20%. Among sub-mitted manuscripts with a similarity score of less than 20%, a larger proportion of the originalresearch and review manuscripts than case reports used more than 10 sources. All articles witha similarity score below 20% were evaluated qualitatively before the final decision of rejection.

      • Absolute binding free energy calculations of CBClip host-guest systems in the SAMPL5 blind challenge

        Lee, Juyong,Tofoleanu, Florentina,Pickard IV, Frank C.,,nig, Gerhard,Huang, Jing,Damjanović,, Ana,Baek, Minkyung,Seok, Chaok,Brooks, Bernard R. Springer-Verlag 2017 Journal of computer-aided molecular design Vol.31 No.1

        <P>Herein, we report the absolute binding free energy calculations of CBClip complexes in the SAMPL5 blind challenge. Initial conformations of CBClip complexes were obtained using docking and molecular dynamics simulations. Free energy calculations were performed using thermodynamic integration (TI) with soft-core potentials and Bennett's acceptance ratio (BAR) method based on a serial insertion scheme. We compared the results obtained with TI simulations with soft-core potentials and Hamiltonian replica exchange simulations with the serial insertion method combined with the BAR method. The results show that the difference between the two methods can be mainly attributed to the van der Waals free energies, suggesting that either the simulations used for TI or the simulations used for BAR, or both are not fully converged and the two sets of simulations may have sampled difference phase space regions. The penalty scores of force field parameters of the 10 guest molecules provided by CHARMM Generalized Force Field can be an indicator of the accuracy of binding free energy calculations. Among our submissions, the combination of docking and TI performed best, which yielded the root mean square deviation of 2.94 kcal/mol and an average unsigned error of 3.41 kcal/mol for the ten guest molecules. These values were best overall among all participants. However, our submissions had little correlation with experiments.</P>

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      • Prevalence and Risk Factors for Helicobacter Pylori Infection among Healthy Inhabitants in Northern Jakarta, Indonesia

        Goto, Yasuyuki,Syam, Ari Fahrial,Darnindro, Nikko,Hapsari, Florentina Carolin Puspita Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.10

        Background: The prevalence of Helicobacter pylori (H. pylori) infection in Indonesia has been reported to be exceedingly low. The purpose of our study was to confirm whether this is the case in Northern Jakarta using a sensitive 13C-urea breath test (UBT), and to examine any associations with lifestyle/environment factors and potential routes of transmission. Methods: We recruited a total of 196 subjects from a low-income community in Northern Jakarta, Indonesia, data from 193 who completed a questionnaire about their lifestyle/environment and had UBT being included as the final. Odds ratios (ORs) adjusted for sex and age with 95% confidence intervals (CIs) were calculated using a logistic regression model. Results: The overall H. pylori infection rate was 15.0% (95%CI, 10.3-20.9), with variation among Javanese (9.1%, total=77), Buginese (40.0%, 35), Betawi (9.1%, 33), Sundanese (3.7%, 27), and Batak (40.0%, 5). On multivariate analysis, the ORs for intake of soybean milk, cucumber more than once a week, infrequent hand washing practice before meals, and alcohol consumption were 0.10 (95%CI: 0.01-0.97), 6.61 (95%CI: 1.87-23.3), 4.10 (95%CI: 1.15-14.6), and 61.9 (95%CI: 1.67-2300.8), respectively. Rates for Buginese (OR=7.84; 95%CI: 1.82-33.8) and Batak (OR=20.1; 95%CI: 1.90-213.2) were significantly higher than for Javanese. Conclusions: The H. pylori infection rate in this study was relatively low, in line with previous studies. Regarding ethnicity factors, Buginese and Batak reported eating food using fingers more frequently than Javanese, Betawi, and Sundanese. Our study indicated that person-person transmission is possible in this low prevalence area. The low infection rates for H. pylori among Javanese, Betawi, and Sundanese ethnics could be partly due to their sanitary practices.

      • Risk Factors for and Prevalence of Helicobacter Pylori Infection among Healthy Inhabitants in Northern Jakarta, Indonesia

        Goto, Yasuyuki,Syam, Ari Fahrial,Darnindro, Nikko,Hapsari, Florentina Carolin Puspita Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.9

        Indonesia is a developing country, in most of which the infection rates of Helicobacter pylori (H. pylori) have been reported to be high. However, the prevalence of H. pylori infection in Indonesia has been unexpectedly reported to be low. The purpose of our study was to confirm whether the prevalence of H. pylori infection is low among healthy inhabitants in Northern Jakarta by 13C-urea breath test (UBT), and to examine the association of their lifestyle/environmental factors with H. pylori infection and to identify potential routes of transmission. We recruited a total of 196 subjects from a low-income community in Northern Jakarta, Indonesia. Of them, 193 subjects who completed a questionnaire about their lifestyle/environment and had UBT were included in this study. Odds ratios (ORs) adjusted for sex and age with 95% confidence intervals (CIs) were calculated using logistic regression model. The overall H. pylori infection rate was 15.0%. There was difference in H. pylori infection rates among Buginese (40.0%), Betawi (9.1%), Sundanese (3.7%), and Batak (9.1%). After multivariate analysis, the ORs of intake of soybean milk, cucumber more than one time a week, infrequent hand washing before meals, and alcohol consumption were 0.10 (95%CI: 0.01-0.97), 6.61 (95%CI: 1.87-23.3), 4.10 (95%CI: 1.15-14.6), and 61.9 for former drinkers (95%CI: 1.67-2300.8), respectively. Buginese (OR=7.84; 95%CI: 1.82-33.8) and Batak ethnic groups (OR=20.1; 95%CI: 1.90-213.2) were infected more frequently, compared with Javanese. The H. pylori infection rate in this study was low, as reported previously. After we scrutinized the factors, Buginese and Batak ethnic groups eat food using fingers more frequently than Javanese, Betawi, and Sundanese. In addition, infrequent hand wash practice before meal increased the risk. Our study indicated that person-person transmission was possible in this low prevalence area. The low infection rates of H. pylori among those of Javanese, Betawi, and Sundanese ethnicity could be partly due to sanitary practice.

      • Poster Session : PS 0114 ; Cardiology : Syncope -A Retrospective Study in an Emergency Hospital

        ( Daniela Bartos ),( Alina Ripa ),( Claudia Negrea ),( Mihaela Hostiuc ),( Cristina Tirziu ),( Florentina Mehic ),( Elisabeta Badila ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background: Syncope is a commonly encountered problem in an emergency hospital. Global cerebral hypoperfusion is the fi nal pathway common to all presentations of syncope, but this symptom presentation has a broad differential diagnosis. It is important to identify patients whose syncope is a symptom of a potentially life-threatening condition. Methods: Adult patients with syncope presenting to the Emergency Hospital from January 2012 to June 2014 were identifi ed. Diagnosis was established retrospectively by reviewing medical records. Results: Of 590 patients found in our hospital`s database we selected 218 patients who met our criteria. The demographics of our group show a slightly different distribution of the incidence between men and women (49% men and 51% women) and a majority of incidence in the urban medium (67%). As for the age range, most of our patients were >80 years old (28%), 22% were in the range of 70-80 years and the percentage decreases signifi cantly in the 60-70 years range (15%). The most frequent causes of syncope were cardiac (32%), vasovagal (23%) and due to orthostatic hypotension (12%), but we have also found various cases of mixt or iatrogenic causes. Conclusions: The incidence of syncope increases sharply after 70 years of age and poses special consideration in light of multiple comorbid conditions, age-related changes, atypical presentation, and concomitant medication use. The most common causes of syncope in this population are cardiac causes, orthostatic hypotension and carotid sinus hypersensitivity. Often, patients remain undiagnosed, despite exhaustive diagnostic testing.

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