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Valadas Sandra T,Fernandes Preciosa,Monteiro Angélica,Figueiredo Carla,Marinho Paulo,Vilhena Carla The Pacific Early Childhood Education Research Ass 2023 Asia-Pacific journal of research in early childhoo Vol.17 No.3
This paper analyses the perceptions of Portuguese preschool teachers regarding the use of Digital Platforms and Technologies (DPTs) in preschool education, focusing on which DPTs are mostly used and with what aims, and on constraints felt in its use. The paper draws on data collected in a larger research project regarding the use of DPTs ) in schools, using a survey questionnaire applied in schools from the Portuguese mainland during 2020, answered by 75 preschool teachers. Results show that preschool teachers mostly use Microsoft Office applications and communication platforms to communicate with peers and families, and for administrative and pedagogical tasks. The constraints felt are associated with the need for training which would allow these professionals to use DPTs more effectively, and the need to upgrade and ensure technical maintenance of the existing equipment.
Sandra Regina B. R. Sella,Carla Masetti,Luis Felipe M. Figueiredo,Luciana P. S. Vandenberghe,João Carlos Minozzo,Carlos Ricardo Soccol 한국생물공학회 2013 Biotechnology and Bioprocess Engineering Vol.18 No.1
A novel cost-effective Bacillus atrophaeus Sterilization Bioindicator System (BIS) with a high quality and performance was developed from a soybean byproduct and compared with the commercial BIS. It was composed of recovery medium and dry-fermented spores with sand as the support. The BIS was developed and optimized using a sequential experimental design strategy. The recovery medium contained soluble starch (1.0 g/L),soybean molasses (30.0 g/L), tryptone (40.0 g/L), and bromothymol blue (0.02 g/L) at pH 8.5. The solid-state fermentation conditions of the bioreactor and environmental humidity had no significant effects on the spore yield and dry-heat resistance. The only substrate mineral that showed a positive effect was Mn2+, allowing Mg2+, K+, and Ca2+ to be eliminated from the formulation. Validation of optimized medium indicated D160°C = 6.8±1.0 min (3.6 min more than the minimum) and spore yield = 2.3 ± 0.5 × 109 CFU/g dry sand (10,000 × initial values). BIS performance resulted in D160°C = 6.6 ± 0.1 min. Sporulation and germination kinetics allowed the sporulation process to be reduced to three days, and the growth of heat-damaged spores was sufficient to achieve visual identification of a non-sterile BIS within 21 h. Process economics was a minimum of 23.9%, and process cycle time was reduced from 29 to 15days. The new BIS parameters demonstrated compliance to all regulatory requirements. No studies have yet described a BIS production from soybean molasses.
Carvalho Bruno Fontenele,de Castro Julia Gonçalves Koehne,de Melo Nilce Santos,de Souza Figueiredo Paulo Tadeu,Moreira-Mesquita Carla Ruffeil,de Paula Ana Patrícia,Sindeaux Rafael,Leite André Ferreira 대한영상치의학회 2022 Imaging Science in Dentistry Vol.52 No.1
Purpose: The aim of this study was to compare the fractal dimension (FD) measured at 2 bone sites (second cervical vertebra and mandible) on cone-beam computed tomography (CBCT). The research question was whether FD could serve as an accessory tool to refer postmenopausal women for densitometric analysis. Therefore, the reliability and accuracy of FD were evaluated. Materials and Methods: In total, 103 postmenopausal women were evaluated, of whom 52 had normal bone mineral density and 51 had osteoporosis, according to dual X-ray absorptiometry of the lumbar spine and hip. On the CBCT scans, 2 regions of interest were selected for FD analysis: 1 at the second cervical vertebra and 1 located at the mandible. The correlations between both measurements, intra- and inter-observer agreement, and the accuracy of the measurements were calculated. A P value less than 0.05 was considered to indicate statistical significance for all tests. Results: The mean FD values were significantly lower at the mandibular region of interest in osteoporotic patients than in individuals with normal bone mineral density. The areas under the curve were 0.644 (P = 0.008) and 0.531 (P = 0.720) for the mandibular and vertebral sites, respectively. Conclusion: FD at the vertebral site could not be used as an adjuvant tool to refer women for osteoporosis investigation. Although FD differed between women with normal BMD and osteoporosis at the mandibular site, it demonstrated low accuracy and reliability.