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RISS 인기검색어
- 검색키워드
- 저자 : Fernando Antunes (검색결과 5 건)
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Study on Mechanical Properties and Fracture in Epoxy Composites Reinforced by Hybrid Twill Fabrics
Jorge Fernando de Sousa Oliveira,Mirtânia Antunes Leão,Ana Claudia Melo Caldas Batista,Sérgio Renan Lopes Tinô,Eve Maria Freire de Aquino 한국섬유공학회 2018 Fibers and polymers Vol.19 No.5
The aim of this study is to determine the influence of hybrid twill fabrics on the conception of polymer composites in terms of their mechanical properties and fracture mechanisms. Parameters associated with the type and/or process of hybridization, such as the presence or not of anisotropy, are influential factors in the final performance of these materials. For this, two composite laminates were manufactured, each containing four layers of reinforced hybrid twill fabrics made from Kevlar-49/AS4 carbon and Kevlar-49/E-glass fibers, with a high-performance epoxy vinyl ester as matrix. Mechanical properties were performed for uniaxial tensile, three-point bending and uniaxial compression tests. The type of hybrid twill fabric directly affected the mechanical properties and damage mechanism of the laminates studied for all loads applied. Highlight that specimens tested to carbon direction exhibited better mechanical behavior.
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The Roles of Peroxiredoxin and Thioredoxin in Hydrogen Peroxide Sensing and in Signal Transduction
Netto, Luis E.S.,Antunes, Fernando Korean Society for Molecular and Cellular Biology 2016 Molecules and cells Vol.39 No.1
A challenge in the redox field is the elucidation of the molecular mechanisms, by which $H_2O_2$ mediates signal transduction in cells. This is relevant since redox pathways are disturbed in some pathologies. The transcription factor OxyR is the $H_2O_2$ sensor in bacteria, whereas Cys-based peroxidases are involved in the perception of this oxidant in eukaryotic cells. Three possible mechanisms may be involved in $H_2O_2$ signaling that are not mutually exclusive. In the simplest pathway, $H_2O_2$ signals through direct oxidation of the signaling protein, such as a phosphatase or a transcription factor. Although signaling proteins are frequently observed in the oxidized state in biological systems, in most cases their direct oxidation by $H_2O_2$ is too slow ($10^1M^{-1}s^{-1}$ range) to outcompete Cys-based peroxidases and glutathione. In some particular cellular compartments (such as vicinity of NADPH oxidases), it is possible that a signaling protein faces extremely high $H_2O_2$ concentrations, making the direct oxidation feasible. Alternatively, high $H_2O_2$ levels can hyperoxidize peroxiredoxins leading to local building up of $H_2O_2$ that then could oxidize a signaling protein (floodgate hypothesis). In a second model, $H_2O_2$ oxidizes Cys-based peroxidases that then through thiol-disulfide reshuffling would transmit the oxidized equivalents to the signaling protein. The third model of signaling is centered on the reducing substrate of Cys-based peroxidases that in most cases is thioredoxin. Is this model, peroxiredoxins would signal by modulating the thioredoxin redox status. More kinetic data is required to allow the identification of the complex network of thiol switches.
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The Roles of Peroxiredoxin and Thioredoxin in Hydrogen Peroxide Sensing and in Signal Transduction
Luis E.S. Netto,Fernando Antunes 한국분자세포생물학회 2016 Molecules and cells Vol.39 No.1
A challenge in the redox field is the elucidation of the molecular mechanisms, by which H2O2 mediates signal transduction in cells. This is relevant since redox pathways are disturbed in some pathologies. The transcription factor OxyR is the H2O2 sensor in bacteria, whereas Cys-based peroxidases are involved in the perception of this oxidant in eukaryotic cells. Three possible mechanisms may be involved in H2O2 signaling that are not mutually exclusive. In the simplest pathway, H2O2 signals through direct oxidation of the signaling protein, such as a phosphatase or a transcription factor. Although signaling proteins are frequently observed in the oxidized state in biological systems, in most cases their direct oxidation by H2O2 is too slow (101 M-1 s-1 range) to outcompete Cys-based peroxidases and glutathione. In some particular cellular compartments (such as vicinity of NADPH oxidases), it is possible that a signaling protein faces extremely high H2O2 concentrations, making the direct oxidation feasible. Alternatively, high H2O2 levels can hyperoxidize peroxiredoxins leading to local building up of H2O2 that then could oxidize a signaling protein (floodgate hypothesis). In a second model, H2O2 oxidizes Cys-based peroxidases that then through thiol-disulfide reshuffling would transmit the oxidized equivalents to the signaling protein. The third model of signaling is centered on the reducing substrate of Cys-based peroxidases that in most cases is thioredoxin. Is this model, peroxiredoxins would signal by modulating the thioredoxin redox status. More kinetic data is required to allow the identification of the complex network of thiol switches.
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LCL Filter design for grid-connected NPC inverters in offshore wind turbines
Samuel Vasconcelos Araujo,Alfred Engler,Benjamin Sahan,Fernando Luiz Marcelo Antunes 전력전자학회 2007 ICPE(ISPE)논문집 Vol.- No.-
This paper deals with the analysis, design and optimization of a LCL filter topology to connect a 7MW NPC inverter to the grid. Following the requirements based on the IEEE 519-1992 recommendation and the German Guideline VDEW, simulation results were evaluated in order to access the performance of the proposed filter and the quality of the current injected into the grid.
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Samuel Vasconcelos Araujo,Peter Zacharias,Benjamin Sahan,Rene P. Torrico Bascope,Fernando L. M. Antunes 전력전자학회 2007 ICPE(ISPE)논문집 Vol.- No.-
Usually considered as one of the future solutions for grid connection of photovoltaic systems, module integrated converters were already the focus of several researches and projects. Most of the proposed approaches relied so far on the use of high frequency step-up transformers either in isolated operation or integrated in isolated dc-dc topologies. This paper analyses the possibility of using non-isolated topologies to achieve the necessary high-voltage gain for grid connection. Several circuits were analyzed and the best suited one for the current application was evaluated and optimized. Experimental results are presented in the final section.
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