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RISS 인기검색어
- 검색키워드
- 저자 : Fauconnier Marie-Laure (검색결과 4 건)
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Chemical Composition and Antioxidant Activity of Algerian Juniperus Phoenicea Essential Oil
Aicha Harhour,Moussa Brada,Marie-Laure Fauconnier,Georges Lognay 한국생약학회 2018 Natural Product Sciences Vol.24 No.2
Berries and branches essential oil of Juniperus phoenicea were obtained by electromagnetic induction heating assisted extraction and by hydrodistillation with a yield varied from (1.2 ? 0.3 to 2.4 ? 0.7%) and from (0.6 ? 0.1% to 1.1 ? 0.1%), respectively. forty eight compounds were identified representing (97.2 - 99.7%) of the oil. a-Pinene (40.3 - 67.8%) and d-3-carene (13.5 - 26.8%) were the main compounds in berries and branches essential oils. Antioxidant activity was evaluated by three means: inhibition of 2, 2-diphenyl-1-picryl hydrazyl (DPPH) free radical, reducing power and b-Carotene/linoleic acid bleaching. The antioxidant activity of essential oils showed IC50 ranging from 67.6 ? 1.02 mg/mL to 131.5 ? 0.8 mg/mL for berries and from 98 ? 1.25 mg/mL to 166.8 ? 0.29 mg/mL for the branches. Berries oil show more potent antioxidant activity compared to branches. This result is supported by the three methods investigated in this work.
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Lamia Sid Ali,Moussa Brada,Marie-Laure Fauconnier,Tierry Kenne 한국생약학회 2018 Natural Product Sciences Vol.24 No.1
The present study deals with the determination of optimal values of operating parameters such as the temperature of heating, the mass of the plant material and the volume of water leading to the best yield of electromagnetic induction (EMI) heating extraction of Algerian Thymus fontanesii essential oil. After an appropriate choice of the three critical variables, eight experiments leaded to a mathematical model as a first-degree polynomial presenting the response function (yield) in the relation to the operating parameters. From the retained model, we were able to calculate the average response, the different effects and their interactions. The maximum of essential oil recovery percentage relative to the initial mass of plant material was 1.69%, and was obtained at (140 oC, 250 g and 4.5 L). The chemical composition of the Algerian T. fontanesii essential oil under the obtained optimal conditions (140 oC, 250 g and 4.5 L), determined by GC/MS and GC/FID, reveled of the presence of major components such as: carvacrol (70.6 ? 0.1%), followed by p-cymene (8.2 ? 0.2%).
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Nemiche Souhila,Ait Hamadouche Nadia,Nemmiche Saïd,Fauconnier Marie-Laure,Tou Abdenacer 한국독성학회 2022 Toxicological Research Vol.38 No.3
Many heavy metals and metalloids (e.g., Pb, Cd, and Ni) can contaminate the environment and cause severe health problems. Through this study, investigated the possible corrective effects of Ficus carica extract (FCE) against nickel (Ni) induced stress response and damage on the liver of rats. Male Wistar rats were divided into four groups (8 rats per group) and cotreated with FCE (350 mg/kg) and exposed to Nickel chloride (10 mg/kg) for 4 weeks. The volatile compounds of FCE were characterized by solid phase micro-extraction (SPME) coupled with GC–MS, and the biochemical parameters of stress were determined. The SPME–GC/MS analysis of FCE indicated the presence of thirty (30) phyto-bioactive compounds including alcohols, aldehydes, organic acids, ketones, furans, terpenes, ester and others. The best capacity for scavenging DPPH free radicals and metal chelating were found with the IC50 values of 0.49 and 2.91 mg/mL, respectively. Ni induced damage to various macromolecules. Malondialdehyde, protein carbonyls, alanine aminotransferase and gamma glutamyl transferarse levels were significantly increased in Ni exposed group compared to control group and co-treatment with FCE reduced the levels of these parameters. In conclusion, current findings showed that Ni-induced oxidative damage and the administration of FCE can improve correct and restore the alteration in the rat liver.
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Chemical Composition of Cactus Pear Seed Oil: phenolics identification and antioxidant activity
Ali, Berraaouan,Abderrahim, Ziyyat,Hassane, Mekhfi,Marianne, Sindic,Marie-Laure, Fauconnier,Abdelkhaleq, Legssyer,Mohammed, Aziz,Mohamed, Bnouham KOREAN PHARMACOPUNCTURE INSTITUTE 2022 Journal of pharmacopuncture Vol.25 No.2
Objectives: The chemical composition of cactus pear seed oil (Opuntia ficus-indica [L.] Mill.) was analyzed in terms of its fatty acid composition, tocopherol content, phenolic identification, and the oil's phenolic-rich fraction antioxidant power was determined. Methods: Fatty acid profiling was performed by gas chromatography coupled to an FI detector. Tocopherols and phenolic compounds were analyzed by LC-FLD/UV, and the oil's phenolic-rich fraction antioxidant power was determined by phosphomolybdenum, DPPH assay and β-carotene bleaching test. Results: Fatty acid composition was marked by a high unsaturation level (83.22 ± 0.34%). The predominant fatty acid was linoleic acid (66.79 ± 0.78%), followed by oleic acid (15.16 ± 0.42%) and palmitic acid (12.70 ± 0.03%). The main tocopherol was γ-tocopherol (172.59 ± 7.59 mg/kg. In addition, Tyrosol, vanillic acid, vanillin, ferulic acid, pinoresinol, and cinnamic acid were identified as phenolic compounds in the analyzed seed oil. Moreover, the oil's phenolics-rich fraction showed a significant total antioxidant activity, scavenged DPPH up to 97.85%, and effectively protected β-carotene against bleaching (97.56%). Conclusion: The results support the potential use of cactus pear seed oil as a functional food.
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