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        Modification of Polyurethane Foams with 1,3,5-Triazine Ring and Boron

        Ewelina Chmiel,Jacek Lubczak,Ryszard Stagraczyński 한국고분자학회 2017 Macromolecular Research Vol.25 No.4

        Boric acid was hydroxyalkylated with glycidol and ethylene carbonate. The product of hydroxyalkylation of boric acid was used to modify oligoetherol obtained from melamine and propylene carbonate. The obtained mixture was further used to get polyurethane foams (PUFs) by reaction with diphenylmethane isocyanate in presence of water. The foaming with diphenylmethane isocyanate containing 30 % tri-functional isocyanates resulted in formation of polyurethane foams of enhanced thermal resistance and diminished flammability in comparison with analogous PUFs based on 1,3,5-triazine ring.

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        Polyurethane Foams with 1,3,5-Triazine Ring and Silicon Atoms

        Jacek Lubczak,Ewelina Chmiel 한국고분자학회 2019 Macromolecular Research Vol.27 No.6

        The method of obtaining polyurethane foams based on two oligoetherols, synthesized from (1) melamine and propylene carbonate, and (2) from metasilicic acid, glycidol and ethylene carbonate, is elaborated. The physical properties of PUFs are tested depending on composition of oligoetherol substrates mixture used. It has been found that 1,3,5-triazine rings in PUF increase their thermal resistance, while silicon contributes to improvement of mechanical properties of PUF. The siliconmodified P U Fs c an s tand l ong term h eating a t 150-200oC with concomitant increase of compression strength and decrease of flammability of PUFs. The PUFs heated at 150 oC for one month become self-extinguishing, or even inflammable upon exposure at 175 oC.

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        Lactobacillus crispatus and its enolase and glutamine synthetase influence interactions between Neisseria gonorrhoeae and human epithelial cells

        Jagoda Płaczkiewicz,Paulina Chmiel,Ewelina Malinowska,Pawel Bącal,Agnieszka Kwiatek 한국미생물학회 2020 The journal of microbiology Vol.58 No.5

        Neisseria gonorrhoeae, an obligatory human pathogen causes the sexually transmitted disease gonorrhea, which remains a global health problem. N. gonorrhoeae primarily infects the mucosa of the genitourinary tract, which in women, is colonized by natural microbiota, dominated by Lactobacillus spp., that protect human cells against pathogens. In this study, we demonstrated that precolonization of human epithelial cells with Lactobacillus crispatus, one of the most prevalent bacteria in the female urogenital tract, or preincubation with the L. crispatus enolase or glutamine synthetase impairs the adhesion and invasiveness of N. gonorrhoeae toward epithelial cells, two crucial steps in gonococcal pathogenesis. Furthermore, decreased expression of genes encoding the proinflammatory cytokines, TNFα and CCL20, which are secreted as a consequence of N. gonorrhoeae infection, was observed in N. gonorrhoeae-infected epithelial cells that had been precolonized with L. crispatus or preincubated with enolase and glutamine synthetase. Thus, our results indicate that the protection of human cells against N. gonorrhoeae infection is a complex process and that L. crispatus and its proteins enolase and glutamine synthetase can have a potential role in protecting epithelial cells against gonococcal infection. Therefore, these results are important since disturbances of the microbiota or of its proteins can result in dysbiosis, which is associated with increased susceptibility of epithelium to pathogens.

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