RISS 학술연구정보서비스

검색
다국어 입력

http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.

변환된 중국어를 복사하여 사용하시면 됩니다.

예시)
  • 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
  • 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
닫기
    인기검색어 순위 펼치기

    RISS 인기검색어

      검색결과 좁혀 보기

      선택해제
      • 좁혀본 항목 보기순서

        • 원문유무
        • 원문제공처
          펼치기
        • 등재정보
          펼치기
        • 학술지명
          펼치기
        • 주제분류
          펼치기
        • 발행연도
          펼치기
        • 작성언어
        • 저자
          펼치기

      오늘 본 자료

      • 오늘 본 자료가 없습니다.
      더보기
      • 무료
      • 기관 내 무료
      • 유료
      • 음악예술문화 이식?

        李如辰 이화여자대학교 음악대학 1993 音樂藝術論壇 Vol.- No.2

        The intent of this article is to follow the development of Asian music from its history before Western influence to the current state of Asian music, and beyond to its future in an increasingly global intellectual community. Accumulated over the centuries in museums are thousands of Asian musical instruments of which the knowledge and skill to play them have been lost. Physical examination of these artifacts may reveal the concepts of Asian music before the exposure to Western ideas. By contrasting the construction of these instruments to their Western counterparts, differences in timbre, articulation, and volume that they produce can be determined which may be attributable to the differing conceptual frameworks of traditional Eastern and Western music. To investigate whether Eastern ideas inherited from the past or Western music theory holds greater validity in contemporary Asian music, works by three outstanding Asian composers of this century are considered, Isang Yun's Reak, Toru Takemitzu's November Steps, and Chou Wen­chung's Cursive. Isang Yun's Reak, which uses a large Western orchestra, imitates some of the sonorities of Korean traditional court music. Toru Takemitzu's November Steps uses two with Japanese solo instruments a Western orchestra. Chou Wen­Chung's Cursive, a duo for flute and piano, utilizes the old Chinese musical concept of the pien­tone, the interpolation of a minor third with a semitone below the upper tone. This concept is built on the principle of the I Ching (Book of Change), the polarities of the positive (yang) and the negative (ying), graphically represented by an unbroken horizontal line and one broken in two respectively. These lines are superposed to beget the eight trigrams (kua) each with three broken and unbroken lines. The musical result suggests a concept similar to that of the osmoglasie except that the piece is totally controlled, including a rhythm as equal as a total serialization. To investigate the impact of the traditions of each culture on the future of contemporary music as it develops in an increasingly globalistic world community, Stravinsky's The Flower, Webern's Op. 17, and Lee's Composition for Flute Solo are analysed to prove that absolute music is nothing but the expression of a logical progression of sounds and not a language of emotions regardless of the time and place in which the pieces are created. Some Asian musical instruments may no longer be in use, because of inferior sound production. However, many instruments along with their underlying musical concepts were lost, not because of any lack in virtue, but because of societal changes in politics, religion, culture, commercialism, stemming in large part to colonization by sociocentric powers. To restore many of the lost virtues to the Asian musical tradition and to revitalize it so that it can contribute to the global intellectual community once again, Asian composers need to break through the limitations imposed by the equal timing system which resulted from the Western development of the keyboard instruments. The minute fluctuations in tone, once the heart of Asian musical instruments, need to be recovered to allow an unbounded freedom of sound. The article suggests that the computer may be the instrument which signals the birth of a new esthetics, (new) tonality, (new) harmony, (new) structure and (new) form, born from the various traditions of a global community.

      • SCIESCOPUSKCI등재
      • SCISCIESCOPUS

        Apolipoprotein B binds to enolase-1 and aggravates inflammation in rheumatoid arthritis

        Lee, Joo Youn,Kang, Min Jueng,Choi, Ji Yong,Park, Ji Soo,Park, Jin Kyun,Lee, Eun Young,Lee, Eun Bong,Pap, Thomas,Yi, Eugene C,Song, Yeong Wook H. K. Lewis 2018 Annals of the rheumatic diseases Vol. No.

        <P>Conclusions A key component of atherogenic lipids, apoB, aggravated arthritis by potentiating the inflammatory response via its interaction with ENO1 expressed on the surface of immune cells. This suggests a novel mechanism by which lipid metabolism regulates chronic inflammation in RA.</P>

      • SCISCIESCOPUS

        Comparative Survey of Rumen Microbial Communities and Metabolites across One Caprine and Three Bovine Groups, Using Bar-Coded Pyrosequencing and<sup>1</sup>H Nuclear Magnetic Resonance Spectroscopy

        Lee, Hyo Jung,Jung, Ji Young,Oh, Young Kyoon,Lee, Sang-Suk,Madsen, Eugene L.,Jeon, Che Ok American Society for Microbiology 2012 Applied and environmental microbiology Vol.78 No.17

        <B>ABSTRACT</B><P>Pyrosequencing of 16S rRNA genes (targetingBacteriaandArchaea) and<SUP>1</SUP>H nuclear magnetic resonance were applied to investigate the rumen microbiota and metabolites of Hanwoo steers in the growth stage (HGS), Hanwoo steers in the late fattening stage (HFS), Holstein-Friesian dairy cattle (HDC), and Korean native goats (KNG) in the late fattening stage. This was a two-part investigation. We began by comparing metabolites and microbiota of Hanwoo steers at two stages of husbandry. Statistical comparisons of metabolites and microbial communities showed no significant differences between HFS and HGS (differing by a dietary shift at 24 months and age [67 months versus 12 months]). We then augmented the study by extending the investigation to HDC and KNG. Overall, pyrosequencing of 16S rRNA genes showed that the rumens had highly diverse microbial communities containing many previously undescribed microorganisms. Bioinformatic analysis revealed that the bacterial sequences were predominantly affiliated with four phyla-Bacteroidetes,Firmicutes,Fibrobacteres, andProteobacteria-in all ruminants. However, interestingly, the bacterial reads belonging toFibrobactereswere present at a very low abundance (@@<@@0.1%) in KNG. Archaeal community analysis showed that almost all of these reads fell into a clade related to, but distinct from, known cultivated methanogens. Statistical analyses showed that the microbial communities and metabolites of KNG were clearly distinct from those of other ruminants. In addition, bacterial communities and metabolite profiles of HGS and HDC, fed similar diets, were distinctive. Our data indicate that bovine host breeds override diet as the key factor that determines bacterial community and metabolite profiles in the rumen.</P>

      • PU nanoweb-based textile electrode treated with single-walled carbon nanotube/silver nanowire and its application to ECG monitoring

        Lee, Eugene,Cho, Gilsoo IOP 2019 Smart materials & structures Vol.28 No.4

        <P>This paper is a research on textile electrodes fabricated by applying single-walled carbon nanotube (SWCNT) and silver nanowire (AgNW) to polyurethane (PU) nanoweb for monitoring electrocardiography (ECG) signals. In order to impart electrical conductivity, PU nanoweb was treated with SWCNT and AgNW. The PU nanoweb was dipped into 15 g of SWCNT dispersion mixed with 5 g of AgNW dispersion, and it was also treated with heat post-treatment and ethanol pre-treatment for enhanced conductivity. The electrical properties were evaluated by electrical linear resistance and impedance. The tensile properties were measured by Instron. By using the treated specimens, the wearable textile sensors were fabricated and verified to properly act as ECG electrodes via wear-trials compared to the conventional ECG electrode. To compare the ECG signals between Ag/AgCl electrode and textile electrodes, morphology of waveforms was compared and statistical analysis was also conducted. The results of the electrical properties showed that specimens SA1-H, SA1-E, and SA1-HE was much lower than SA1, and especially, SA1-H showed the lowest resistance. It corresponded to the results of impedance that specimen SA1 had the highest and specimen SA1-H had the lowest value. The results of the tensile properties showed that specimen SA1-H had higher tensile strength and elongation at break than the untreated. And, the results of the wear-trials showed that specimen SA1-H had the performance for ECG signals monitoring regardless of rest/stress-states, age, sex, and BMI index of the participants. Thus, it confirmed that the wearable textile sensors fabricated by using the SWCNT/AgNW treated PU nanoweb was suitable for ECG monitoring. Based on the results, it should have approximately 10 Ω cm<SUP>−1</SUP> when applied as the ECG electrode for long-term bio-monitoring smart clothing.</P>

      • SCISCIESCOPUS

        18F-FDG PET/CT features of pulmonary sclerosing hemangioma.

        Lee, Eugene,Park, Chang Min,Kang, Keon Wook,Goo, Jin Mo,Kim, Min A,Paeng, Jin Chul,Lee, Hyun Ju,Park, Heae Surng,Chung, Doo Hyun Acta Radiologica] 2013 Acta radiologica Vol.54 No.1

        <P>Pulmonary sclerosing hemangioma (PSH) has been reported to show increased FDG uptake and be potential false-positives on 18F-FDG PET/CT examination. However, it is still unclear whether the previously-reported high FDG uptake is a universal characteristic of PSH, and furthermore, there have been no investigations on what kind of radiologic or histologic features may have been related with its FDG uptake values.</P>

      • ANKRD9 is associated with tumor suppression as a substrate receptor subunit of ubiquitin ligase

        Lee, Yejin,Lim, Byungho,Lee, Seon Woo,Lee, Woo Rin,Kim, Yong-In,Kim, Minhyeok,Ju, Hyoungseok,Kim, Mi Young,Kang, Suk-Jo,Song, Ji-Joon,Lee, J. Eugene,Kang, Changwon Elsevier 2018 Biochimica et biophysica acta. Molecular basis of Vol.1864 No.10

        <P><B>Abstract</B></P> <P><B>Background</B></P> <P>Human <I>ANKRD9</I> (ankyrin repeat domain 9) expression is altered in some cancers.</P> <P><B>Methods</B></P> <P>We tested genetic association of ANKRD9 with gastric cancer susceptibility and examined functional association of ANKRD9 with altered proliferation of MKN45 gastric cancer cells. We then identified ANKRD9-binding partners in HEK 293 embryonic kidney cells using quantitative proteomics, western blotting and complex reconstitution assays. We finally demonstrated ANKRD9's role of recognizing substrates for ubiquitination using in vitro ubiquitylation assay.</P> <P><B>Results</B></P> <P> <I>ANKRD9</I> is associated with cancer susceptibility in a comparison of single-nucleotide polymorphisms between 1092 gastric cancer patients and 1206 healthy controls. ANKRD9 depletion accelerates tumor progression by increasing cellular proliferation, piling up, and anchorage-independent growth of MKN45 cells. We discovered that ANKRD9 is a ubiquitin ligase substrate receptor subunit and has an anti-proliferative activity. ANKRD9 associates with CUL5 (not CUL2), ELOB, ELOC, and presumably RNF7 subunits, which together assemble into a cullin-RING superfamily E3 ligase complex. ANKRD9 belongs to the ASB family of proteins, which are characterized by the presence of ankyrin repeats and a SOCS box. In addition to its interactions with the other E3 ligase subunits, ANKRD9 interacts with two isoforms of inosine monophosphate dehydrogenase (IMPDH). These IMPDH isoforms are cognate substrates of the ANKRD9-containing E3 enzyme, which ubiquitinates them for proteasomal degradation. Their ubiquitination and turnover require the presence of ANKRD9.</P> <P><B>Conclusion</B></P> <P>ANKRD9, a previously unidentified E3 substrate receptor subunit, functions in tumor suppression by recognizing the oncoprotein IMPDH isoforms for E3 ubiquitination and proteasomal degradation.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Human <I>ANKRD9</I> is genetically associated with gastric cancer susceptibility. </LI> <LI> ANKRD9 protein activity is functionally associated with tumor suppression. </LI> <LI> ANKRD9 is a substrate receptor subunit of CUL5-based ubiquitin ligase E3 complex. </LI> <LI> E3 with ANKRD9 ubiquitinates substrate proteins for proteasomal degradation. </LI> <LI> Two isoforms of oncoprotein IMP dehydrogenase are cognate substrates of ANKRD9. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

      연관 검색어 추천

      이 검색어로 많이 본 자료

      활용도 높은 자료

      해외이동버튼