http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : El-Ghar, G.E.A. (검색결과 1 건)
- 무료
- 기관 내 무료
- 유료
-
Yoon, K.S.,Previte, D.J.,Hodgdon, H.E.,Poole, B.C.,Kwon, D.H.,El-Ghar, G.E.A.,Lee, S.H.,Clark, J.M. ESA ENTOMOLOGICAL SOCIETY OF AMERICA 2014 Journal of medical entomology Vol.51 No.2
The study examines the extent and frequency of a knockdown-type resistance allele ( kdr type) in North American populations of human head lice. Lice were collected from 32 locations in Canada and the United States. DNA was extracted from individual lice and used to determine their zygosity using the serial invasive signal amplification technique to detect the kdr-type T917I ( TI) mutation, which is most responsible for nerve insensitivity that results in the kdr phenotype and permethrin resistance. Previously sampled sites were resampled to determine if the frequency of the TI mutation was changing. The TI frequency was also reevaluated using a quantitative sequencing method on pooled DNA samples from selected sites to validate this population genotyping method. Genotyping substantiated that TI occurs at high levels in North American lice ( 88.4%). Overall, the TI frequency in U. S. lice was 84.4% from 1999 to 2009, increased to 99.6% from 2007 to 2009, and was 97.1% in Canadian lice in 2008. Genotyping results using the serial invasive signal ampli_cation reaction ( 99.54%) and quantitative sequencing ( 99.45%) techniques were highly correlated. Thus, the frequencies of TI in North American head louse populations were found to be uniformly high, which may be due to the high selection pressure from the intensive and widespread use of the pyrethrins- or pyrethroid- based pediculicides over many years, and is likely a main cause of increased pediculosis and failure of pyrethrins- or permethrin- based products in Canada and the United States. Alternative approaches to treatment of head lice infestations are critically needed.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
