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        Mechanical Eye Model for Evaluating Intraocular Pressure Measurements

        Kutaiba Saleh,Volkmar Unger,Alexander Dietzel,Detlef Heydenreich,Rico Großjohann,Clemens Jürgens,Frank Tost,Jens Haueisen 대한의용생체공학회 2014 Biomedical Engineering Letters (BMEL) Vol.4 No.4

        Purpose For the development of new intraocular pressure(IOP) measurement devices, as well as for comparison withexisting devices it is important to consider the variousbiomechanical properties of the eye in test setups. Therefore,a controllable physical phantom with flexibility in theadjustment of biomechanical parameters and geometries isbeing proposed and analyzed. Methods Different configurations of a mechanical eyemodel are simulated together with the applanation process,based on the finite element method (FEM). Forming toolsare designed to produce artificial corneas with variablethicknesses and stiffness’s using injection molding. Anapparatus is assembled for controlling and evaluating thephantom eye in connection with a piezoelectric IOP testsensor. Measurements are also performed using thecommercially available non-contact tonometer NCT-800. Results Simulation results for surface pressure and stressdistribution at the cornea together with the pressure in thecentral part of the applanation body show that the pressurereaches a maximum when the local stress is centrallyconcentrated and decreases to a stable level afterwards. Morerigid corneas result in higher maximum values for thepressure. The measurements with the piezoelectric IOP testsensor are in good agreement with the simulation results. The NCT-800 measurements show a significant influence of the biomechanical properties of the cornea on measured IOPs. Conclusion Our phantom is suitable for describing the effectof biomechanical characteristics of the human eye ontonometric measurements and will facilitate the evaluation ofnew tonometry systems.

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