Transcending Cultural Boundaries

Demetrios Th. Vassiliades 한국동서비교문학학회 2013 동서 비교문학저널 Vol.0 No.29

This paper examines the philosophical pursuit of two eminent figures of the modern Greek and world culture, who lived, worked and embraced spiritual traditions, different from those they were born in. Demetrios Galanos lived and worked in India. He is the first Greek Indologist, who made the Sanskrit literature and philosophical thought known to the Greek reader. Lafcadio Hearn, known also by his Japanese name Koizumi Yakumo, spent the last part of his life in Japan. His pioneering books convey the glimpses of an unfamiliar Japan to the western world. Besides, the present study highlights the ways both men followed to overcome the cultural restrictions they experienced in their personal lives, and how those expanded their global understanding and affected their works.

Endovascular Management in Abdominal, Neck and Extremity Vascular Trauma

Demetrios Demetriades 대한외과학회 2021 대한외과학회 학술대회 초록집 Vol.2021 No.11

Environmental assessment of a BIPV system

Demetrios N. Papadopoulos,Constantinos N. Antonopoulos,Vagelis G. Papadakis Techno-Press 2022 Advances in energy research Vol.8 No.1

The application of Photovoltaic (PV) power in the building sector, is expanding as part of the ongoing energy transition into renewables. The article addresses the question of sustainability of energy generated from PVs through an environmental assessment of a building-integrated PV system (BIPV) connected to the grid through net metering. Employing retrospective life cycle analysis (LCA), with the CCaLC2 software and ecoinvent data, the article shows that the carrying structure and other balance of system (BOS) components are responsible for a three times higher energy payback time than the literature average. However, total environmental impact can be lowered through reuse or reinstallation of PVs on the same building structure after the 30-year interval. Further ways to improve environmental efficiency include identifying the most polluting materials for each LCA parameter. The results of this study are of interest to researchers and producers of PVs and organizations investing and promoting decentralized power production through PVs.

Amino acid-insensitive mTORC1 regulation enables nutritional stress resilience in hematopoietic stem cells

Kalaitzidis, Demetrios,Lee, Dongjun,Efeyan, Alejo,Kfoury, Youmna,Nayyar, Naema,Sykes, David B.,Mercier, Francois E.,Papazian, Ani,Baryawno, Ninib,Victora, Gabriel D. American Society for Clinical Investigation 2017 The Journal of clinical investigation Vol.127 No.4

RECENT DEVELOPMENTS IN NONLINEAR HYPERBOLIC PDE

Christodoulou, Demetrios Korean Mathematical Society 2001 대한수학회지 Vol.38 No.4

In this lecture I shall discuss some recent progress in the development of methods for attacking the central questions of the formation and structure of singularities and of global regularity for solutions of the Cauchy problem for nonlinear systems of partial differential equations of hyperbolic type. Applications to the Einstein equations of general relativity and to the equations of compressible fluid flow shall be particularly emphasized and detailed.

Behaviour of steel-fibre-reinforced concrete beams under high-rate loading

Pegah Behinaein,Demetrios M. Cotsovos,Ali A. Abbas 사단법인 한국계산역학회 2018 Computers and Concrete, An International Journal Vol.22 No.3

The present study focuses on examining the structural behaviour of steel-fibre-reinforced concrete (SFRC) beams under high rates of loading largely associated with impact problems. Fibres are added to the concrete mix to enhance ductility and energy absorption, which is important for impact-resistant design. A simple, yet practical non-linear finite-element analysis (NLFEA) model was used in the present study. Experimental static and impact tests were also carried out on beams spanning 1.3 meter with weights dropped from heights of 1.5 m and 2.5 m, respectively. The numerical model realistically describes the fullybrittle tensile behaviour of plain concrete as well as the contribution of steel fibres to the post-cracking response (the latter was allowed for by conveniently adjusting the constitutive relations for plain concrete, mainly in uniaxial tension). Suitable material relations (describing compression, tension and shear) were selected for SFRC and incorporated into ABAQUS software Brittle Cracking concrete model. A more complex model (i.e., the Damaged Plasticity concrete model in ABAQUS) was also considered and it was found that the seemingly simple (but fundamental) Brittle Cracking model yielded reliable results. Published data obtained from drop-weight experimental tests on RC and SFRC beams indicates that there is an increase in the maximum load recorded (compared to the corresponding static one) and a reduction in the portion of the beam span reacting to the impact load. However, there is considerable scatter and the specimens were often tested to complete destruction and thus yielding post-failure characteristics of little design value and making it difficult to pinpoint the actual load-carrying capacity and identify the associated true ultimate limit state (ULS). To address this, dynamic NLFEA was employed and the impact load applied was reduced gradually and applied in pulses to pinpoint the actual failure point. Different case studies were considered covering impact loading responses at both the material and structural levels as well as comparisons between RC and SFRC specimens. Steel fibres were found to increase the load-carrying capacity and deformability by offering better control over the cracking process concrete undergoes and allowing the impact energy to be absorbed more effectively compared to conventional RC members. This is useful for impact-resistant design of SFRC beams.

Covariance patterns between ramus morphology and the rest of the face: A geometric morphometric study

Marietta Krüsi,Demetrios J. Halazonetis,Theodore Eliades,Vasiliki Koretsi 대한치과교정학회 2023 대한치과교정학회지 Vol.53 No.3

Objective: The growth and development of the mandible strongly depend on modeling changes occurring at its ramus. Here, we investigated covariance patterns between the morphology of the ramus and the rest of the face. Methods: Lateral cephalograms of 159 adults (55 males and 104 females) with no history of orthodontic treatment were collected. Geometric morphometrics with sliding semi-landmarks was used. The covariance between the ramus and face was investigated using a two-block partial least squares analysis (PLS). Sexual dimorphism and allometry were also assessed. Results: Differences in the divergence of the face and anteroposterior relationship of the jaws accounted for 24.1% and 21.6% of shape variation in the sample, respectively. Shape variation was greater in the sagittal plane for males than for females (30.7% vs. 17.4%), whereas variation in the vertical plane was similar for both sexes (23.7% for males and 25.4% for females). Size-related allometric differences between the sexes accounted for the shape variation to a maximum of 6% regarding the face. Regarding the covariation between the shapes of the ramus and the rest of the face, wider and shorter rami were associated with a decreased lower anterior facial height as well as a prognathic mandible and maxilla (PLS 1, 45.5% of the covariance). Additionally, a more posteriorly inclined ramus in the lower region was correlated with a Class II pattern and flat mandibular plane. Conclusions: The width, height, and inclination of the ramus were correlated with facial shape changes in the vertical and sagittal planes.

A novel method for testing accuracy of bite registration using intraoral scanners

Lydia Kakali,Demetrios J. Halazonetis 대한치과교정학회 2023 대한치과교정학회지 Vol.53 No.4

Neuroprotective effects of <i>Scrophularia buergeriana</i> extract against glutamate-induced toxicity in SH-SY5Y cells

Lee, Hae Jin,Spandidos, Demetrios A.,Tsatsakis, Aristidis,Margina, Denisa,Izotov, BorisN.,Yang, Seung Hwan UNKNOWN 2019 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE Vol.43 No.5

<P>The aim of this study was to investigate the antioxidant and anti-apoptotic activities, as well as the underlying mechanisms of action, of <I>Scrophularia buergeriana</I> (<I>S. buergeriana</I>) extract (SBE) in glutamate-induced SH-SY5Y cell death. The roots of <I>S. buergeriana</I> were extracted with 70% ethanol, and standardized SBE was used in this study. To induce cytotoxicity, the SH-SY5Y cells were exposed to glutamate for 3 h, or pre-treated with SBE for 1 h, and subsequently incubated with glutamate for 3 h. The neuro-protective effects were assessed by measuring cell viability and the total glutathione contents using commercial kits. The antioxidant and anti-apoptotic mechanisms of action of SBE were evaluated by western blot analysis. The results confirmed that glutamate-induced toxicity was caused by reactive oxygen species (ROS) production, leading to oxidative stress and DNA damage, thus leading to cell death. However, treatment of the SH-SY5Y cells with SBE significantly increased the viability of the cells exposed to glutamate by upregulating the levels of antioxidant proteins, such as superoxide dismutase (SOD)1, SOD2 and glutathione peroxidase-1 (GPx-1), and directly enhancing the total glutathione contents. Furthermore, SBE attenuated DNA impairment and decreased B-cell lymphoma-2 (Bcl-2)-associated X protein (Bax), cleaved caspase-3 and cleaved poly(adenosine diphosphate (ADP)-ribose) polymerase (PARP) activation. In addition, SBE upregulated Bcl-2 expression via p38 mitogen-activated protein kinases (MAPKs). On the whole, the findings of this study demonstrated that SBE exerts neuroprotective effects against glutamate-induced cell toxicity through its antioxidant and anti-apoptotic activities.</P>

Characteristic features of concrete behaviour: Implications for the development of an engineering finite-element tool

Michael D. Kotsovos,Demetrios M. Cotsovos,Milija N. Pavlovic 사단법인 한국계산역학회 2008 Computers and Concrete, An International Journal Vol.5 No.3

The present article summarises the fundamental characteristics of concrete behaviour which underlie the formulation of an engineering finite element model capable of realistically predicting the behaviour of (plain or reinforced) concrete structural forms in a wide range of problems ranging from static to impact loading without the need of any kind of re-calibration. The already published evidence supporting the proposed formulation is complemented by four additional typical case studies presented herein; for each case, a comparative study is carried out between numerical predictions and the experimental data which reveals good agreement. Such evidence validates the material characteristics upon which the FE model’s formulation is based and provides an alternative explanation regarding the behaviour of structural concrete and how it should be modelled which contradicts the presently (widely) accepted assumptions adopted in the majority of FE models used to predict the behaviour of concrete.