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Byeng Wha Son,Dahai Zhang,Dedi Noviendri,Muhammad Nursid,Xiudong Yang 한국생약학회 2007 Natural Product Sciences Vol.13 No.3
Dioxopiperazine alkaloids, 12R,13S 1), fumitremorgin C (2), andbrevianamide F (3), were isolated from the marine-derived fungus Pseudallescheria, and the absolutestereostructures of compounds 1 -3 were elucidated on the basis of chemical and physicochemical evidence.Compounds 1 -3 showed an antibacterial activity against Staphylococcus aureus, methicillin-resistant S. aureus,and multidrug-resistant . The MIC (minimum inhibitory concentration) values of compounds 1 -3 were125 g/mL for all strains. Keywords Marine-derived fungus, Pseudallescheria sp., 12,13-dihydroxyfumitremorgin C, fumitremorgin C,brevianamide F, antibacterial activity