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      • KCI등재

        Use of natural ingredients in Japanese quail diet and their effect on carcass and meat quality — A review

        Rey David Vargas-Sanchez,Felix Joel Ibarra-Arias,Brisa del Mar Torres-Martinez,Armida Sanchez-Escalante,Gaston Ramon Torrescano-Urrutia 아세아·태평양축산학회 2019 Animal Bioscience Vol.32 No.11

        The present paper reviews the findings of different research studies on the effect of natural ingredients in the Japanese quail (Coturnix coturnix japonica) diet on carcass characteristics and meat quality. The results show a relationship between the type and concentration of ingredients used in diets and carcass characteristics and meat quality. The inclusion of medicinal herbs (thyme, black seed, and mint), plants (canola), seeds (chickpea), spices (cinnamon and coriander), worms (earthworms), bee products (propolis), phytochemicals (lycopene), and edible fungi (common mushrooms) in the diet improved carcass quality characteristics compared to the control diets (basal diets). The inclusion of medicinal herbs (spearmint and green tea), spices (cinnamon), vegetables (tomato), plants (verbena and canola), seeds (marijuana), and edible fungi (oyster mushrooms) improved meat quality. In conclusion, the use of ingredients of natural origin in the diet of Japanese quail improves carcass quality characteristics and meat quality.

      • On Line 시스템에 의한 실시간 입도측정 및 분쇄의 자동제어

        Vargas Mariola Lopez,Hernandez Francisco Ayuso,Vilchez Francisco Martinez,Pugh David,Blasco Alain 한국시멘트협회 2004 시멘트 심포지움 Vol.31 No.-

        온라인 분쇄입도 조절 콘트롤(Insitec) 시스템은 시멘트의 생산공정상에 시멘트입도를 직접 측정하고 측정된 데이터를 이용하여 공정을 제어할수 있는 새로운 방법으로서, 세계적으로 50여개의 시멘트 생산 현장에 이러한 시스템이 설치되어 있다. 시멘트의 생산공정은 일반적인 분쇄공정과는 차별되는 나름데로의 특성이 있으므로 이를 개발한 Malvern Instrument사(영국)에서는 시멘트 공장의 특성에 적합한 시스템을 개발해왔다. 우선 가장 이상적인 Instec 시스템의 설치를 위해서는 다음과 같이 3단계의 절차가 필요하다. 첫 단계로서 공정상의 변수로 적용되어야 될 변화를 찾아 모니터링하고 연관시키는 것이다. 그 다음 단계에서, 시멘트 생산공정을 24시간 동안 모니터링하여 설정 값과 측정 값과의 차이점과 원인을 찾아내어 요인을 결정하게 되고, 마지막 단계에서는 현장에 장비를 설치, 상기의 반복과정을 마무리하고 공정을 제어할 수 있게 하는 것이다. 시멘트 생산공정에서 분쇄기, 분급기 및 송풍기 등의 회전수 증가와 감소, 시멘트조성의 변화와 같은 중요한 공정상의 변화가 있을 경우, 이로 인해 생기는 입도의 영향은 Insitec 시스템의 입도관리에 기록되게 된다. 본 논문에서는 스페인의 Jerez에 있는 Holcim 플랜트에 설치된 Insitech를 이용하여 운전상의 변수 등을 측정하고 제어하며 시멘트 공정에 활용하는 방안에 대한 연구를 소개한 것이다.

      • KCI등재

        U6 is unsuitable for normalization of serum miRNA levels in patients with sepsis or liver fibrosis

        Fabian Benz,Christoph Roderburg,David Vargas Cardenas,Mihael Vucur,Jeremie Gautheron,Alexander Koch,Henning Zimmermann,Jorn Janssen,Lukas Nieuwenhuijsen,Mark Luedde,Norbert Frey,Frank Tacke,Christian 생화학분자생물학회 2013 Experimental and molecular medicine Vol.45 No.9

        MicroRNA (miRNA) levels in serum have recently emerged as potential novel biomarkers for various diseases. miRNAs are routinely measured by standard quantitative real-time PCR (qPCR); however, the high sensitivity of qPCR demands appropriate normalization to correct for nonbiological variation. Presently, RNU6B (U6) is used for data normalization of circulating miRNAs in many studies. However, it was suggested that serum levels of U6 themselves might differ between individuals. Therefore, no consensus has been reached on the best normalization strategy in ‘circulating miRNA’. We analyzed U6 levels as well as levels of spiked-in SV40-RNA in sera of 44 healthy volunteers, 203 intensive care unit patients and 64 patients with liver fibrosis. Levels of U6 demonstrated a high variability in sera of healthy donors, patients with critical illness and liver fibrosis. This high variability could also be confirmed in sera of mice after the cecal ligation and puncture procedure. Most importantly, levels of circulating U6 were significantly upregulated in sera of patients with critical illness and sepsis compared with controls and correlated with established markers of inflammation. In patients with liver fibrosis, U6 levels were significantly downregulated. In contrast, levels of spiked-in SV40 displayed a significantly higher stability both in human cohorts (healthy, critical illness,liver fibrosis) and in mice. Thus, we conclude that U6 levels in the serum are dysregulated in a disease-specific manner. Therefore, U6 should not be used for data normalization of circulating miRNAs in inflammatory diseases and previous studies using this approach should be interpreted with caution. Further studies are warranted to identify specific regulatory processes of U6 levels in sepsis and liver fibrosis.

      • KCI등재

        Control of Supercritical Organic Rankine Cycle based Waste Heat Recovery System using Conventional and Fuzzy Self-Tuned PID Controllers

        Jahedul Islam Chowdhury,David Thornhill,Payam Soulatiantork,Yukun Hu,Nazmiye Balta-Ozkan,Liz Varga,Bao Kha Nguyen 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.11

        This research develops a supercritical organic Rankine cycle (ORC) based waste heat recovery (WHR) system for control system simulation. In supercritical ORC-WHR systems, the evaporator is a main contributor to the thermal inertia of the system, which is greatly affected by transient heat sources during operation. In order to capture the thermal inertia of the system and reduce the computation time in the simulation process, a fuzzybased dynamic evaporator model was developed and integrated with other component models to provide a complete dynamic ORC-WHR model. This paper presents two control strategies for the ORC-WHR system: evaporator temperature control and expander output control, and two control algorithms: a conventional PID controller and a fuzzy-based self-tuning PID controller. The performances of the proposed controllers are tested for set point tracking and disturbance rejection ability in the presence of steady and transient thermal input conditions. The robustness of the proposed controllers is investigated with respect to various operating conditions. The results show that the fuzzy self-tuning PID controller outperformed the conventional PID controller in terms of set point tracking and disturbance rejection ability at all conditions encountered in the paper.

      • KCI등재후보

        Brain-lung interaction: a vicious cycle in traumatic brain injury

        Ariana Alejandra Chacón-Aponte,Érika Andrea Durán-Vargas,Jaime Adolfo Arévalo-Carrillo,Iván David Lozada-Martínez,Maria Paz Bolaño-Romero,Moscote-Salazar Luis Rafael,Pedro Grille,Janjua Tariq 대한중환자의학회 2022 Acute and Critical Care Vol.37 No.1

        The brain-lung interaction can seriously affect patients with traumatic brain injury, triggering a vicious cycle that worsens patient prognosis. Although the mechanisms of the interaction are not fully elucidated, several hypotheses, notably the “blast injury” theory or “double hit” model, have been proposed and constitute the basis of its development and progression. The brain and lungs strongly interact via complex pathways from the brain to the lungs but also from the lungs to the brain. The main pulmonary disorders that occur after brain injuries are neurogenic pulmonary edema, acute respiratory distress syndrome, and ventilator-associated pneumonia, and the principal brain disorders after lung injuries include brain hypoxia and intracranial hypertension. All of these conditions are key considerations for management therapies after traumatic brain injury and need exceptional case-by-case monitoring to avoid neurological or pulmonary complications. This review aims to describe the history, pathophysiology, risk factors, characteristics, and complications of brain-lung and lung-brain interactions and the impact of different old and recent modalities of treatment in the context of traumatic brain injury.

      • KCI등재

        Nonlinear earthquake capacity of slender old masonry structures prestressed with steel, FRP and NiTi SMA tendons

        Adolfo Preciado,Alejandro Ramírez-Gaytan,Nayar Gutierrez,David Vargas,Jose Manuel Falcon,Gil Ochoa 국제구조공학회 2018 Steel and Composite Structures, An International J Vol.26 No.2

        This paper focuses on the seismic protection of slender old masonry structures by the implementation of prestressing devices at key locations. The devices are vertically and externally located inside the towers in order to be reversible and calibrated. An extensive parametric study on a selected slender tower is carried out based on more than 100 nonlinear static simulations aimed at investigating the impact of different parameters on the seismic performance: (i) different prestressing levels; (ii) shape memory alloy superelasticity and (iii) changes in prestressing-forces in all the stages of the analysis until failure and masonry toe crushing. The tendon materials under analysis are conventional prestressing steel, fiber-reinforced polymers of different fibers and shape memory alloys. The parametric study serves to select the most suitable prestressing device and optimal prestressing level able to dissipate more earthquake energy. The seismic energy dissipation is evaluated by comparing the structural capacity curves in original state and retrofitted.

      • Photoactive Organic/Inorganic Hybrid Materials with Nanosegregated Donor–Acceptor Arrays

        Fabrice Mathevet,Xiaolei Zhu,Cheriehan Hessin,Aude Salam,Lydia Sosa-Vargas,David Kreher,Chihaya Adachi,Anna Proust,Pierre Mialane,Jerome Marrot,Aude Bouchet,Michel Sliwa,Stephane Mery,Benoit Heinrich 한국고분자학회 2021 한국고분자학회 학술대회 연구논문 초록집 Vol.46 No.2

        We designed and synthesized a first example of mesogenic donor-acceptor polyoxometalate (POM)-based hybrid. The structural and electronic properties of the hybrid compound were evaluated through combination of small- and wide-angle X-ray scattering, optical microscopy, electrochemistry and photoluminescence. In the solid state, the compound behaves as a birefringent solid, displaying a lamellar organization in which double-layers of POMs and bis(thiophene)thienothiophene organic donors alternate regularly. Noticeably, the subunit organizations in the composite are similar to that observed for the individual POM and organic donor precursors. Photophysical studies showed that in the hybrid, the fluorescence of the organic donor unit is considerably quenched both in solution and in the solid state, which is attributed to occurrence of intramolecular charge-separated state.

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