http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Gil Pérez Marta,Mindermann Pascal,Zechmeister Christoph,Forster David,Guo Yanan,Hügle Sebastian,Kannenberg Fabian,Balangé Laura,Schwieger Volker,Middendorf Peter,Bischoff Manfred,Menges Achim,Gresser 한국CDE학회 2023 Journal of computational design and engineering Vol.10 No.4
The linear design workflow for structural systems, involving a multitude of iterative loops and specialists, obstructs disruptive innovations. During design iterations, vast amounts of data in different reference systems, origins, and significance are generated. This data is often not directly comparable or is not collected at all, which implies a great unused potential for advancements in the process. In this paper, a novel workflow to process and analyse the data sets in a unified reference frame is proposed. From this, differently sophisticated iteration loops can be derived. The developed methods are presented within a case study using coreless filament winding as an exemplary fabrication process within an architectural context. This additive manufacturing process, using fiber-reinforced plastics, exhibits great potential for efficient structures when its intrinsic parameter variations can be minimized. The presented method aims to make data sets comparable by identifying the steps each data set needs to undergo (acquisition, pre-processing, mapping, post-processing, analysis, and evaluation). These processes are imperative to provide the means to find domain interrelations, which in the future can provide quantitative results that will help to inform the design process, making it more reliable, and allowing for the reduction of safety factors. The results of the case study demonstrate the data set processes, proving the necessity of these methods for the comprehensive inter-domain data comparison.
Demographics, Usage Patterns, and Safety of Male Users of Clomiphene in the United States
David P. Guo,Dimitar V. Zlatev,Shufeng Li,Laurence C. Baker,Michael L Eisenberg 대한남성과학회 2020 The World Journal of Men's Health Vol.38 No.2
Purpose: The aim of this study was to characterize the demographics, usage patterns and complication rates of clomiphene use in male patients. Materials and Methods: We retrospectively analyzed male patients from ages 20 to 55 years old who were prescribed clomiphene citrate from 2001 to 2014 using the Truven Health MarketScan, a US claims database. We collected data regarding associated medical diagnoses, diagnostic testing, duration of use, and reported side effects including thrombotic events, vision problems, gynecomastia, mental disorders, liver disease, nausea, or skin problems. Results: In total, 12,318 men took clomiphene and represented the primary study cohort, with a mean age of 37.8 years. The percentage of men prescribed clomiphene increased over the study period, as did the average age of clomiphene users. Associated diagnoses included male infertility (52.0%), testicular hypofunction (13.5%), erectile dysfunction (2.4%), and low libido (0.4%). Associated testing included semen analysis (43.7%), testosterone (23.5%), luteinizing hormone (19.3%), and follicle-stimulating hormone (21.1%) levels. The median time of clomiphene use was 3.6 months, with 63% of men stopping within 6 months. No increased risk of reported clomiphene side effects were apparent in men taking the medication. Conclusions: There is a rising prevalence of clomiphene usage without associated adverse side effects in the US. The variability in associated diagnoses, diagnostic testing, and duration of use suggest a need for greater awareness of the proper evaluation and treatment of the men who are prescribed clomiphene.
Modelling the redshift-space three-point correlation function in SDSS-III
Guo, Hong,Zheng,Jing, Y. P.,Zehavi, Idit,Li, Cheng,Weinberg, David H.,Skibba, Ramin A.,Nichol, Robert C.,Rossi, Graziano,Sabiu, Cristiano G.,Schneider, Donald P.,McBride, Cameron K. Oxford University Press 2015 Monthly notices of the Royal Astronomical Society. Vol.449 No.1
Cao, Duyen H.,Guo, Peijun,Mannodi-Kanakkithodi, Arun,Wiederrecht, Gary P.,Gosztola, David J.,Jeon, Nari,Schaller, Richard D.,Chan, Maria K. Y.,Martinson, Alex B. F. American Chemical Society 2019 ACS APPLIED MATERIALS & INTERFACES Vol.11 No.9
<P>Lead halide perovskites present a versatile class of solution-processable semiconductors with highly tunable bandgaps that span ultraviolet, visible, and near-infrared portions of the spectrum. We explore phase-separated chloride and iodide lead perovskite mixtures as candidate materials for intermediate band applications in future photovoltaics. X-ray diffraction and scanning electron microscopy reveal that deposition of precursor solutions across the MAPbCl<SUB>3</SUB>/MAPbI<SUB>3</SUB> composition space affords quasi-epitaxial cocrystallized films, in which the two perovskites do not alloy but instead remain phase-segregated. First-principle calculations further support the formation of an epitaxial interface and predict energy offsets in the valence band and conduction band edges that could result in intermediate energy absorption. The charge dynamics of variable mixtures of the relatively narrow bandgap (1.57 eV) MAPbI<SUB>3</SUB> perovskite and wide bandgap (3.02 eV) MAPbCl<SUB>3</SUB> are probed to map charge and energy flow direction and kinetics. Time-resolved photoluminescence and transient absorption measurements reveal charge transfer of photoexcited carriers in MAPbCl<SUB>3</SUB> to MAPbI<SUB>3</SUB> in tens of picoseconds. The rate of quenching can be further tuned by replacing MAPbI<SUB>3</SUB> with two-dimensional Ruddlesden-Popper (BA)<SUB>2</SUB>(MA)<SUB><I>n</I>−1</SUB>Pb<I><SUB>n</SUB></I>I<SUB>3<I>n</I>+1</SUB> (<I>n</I> = 3, 2, and 1) perovskites, which also remain phase-separated.</P> [FIG OMISSION]</BR>
Eichhorn, Stephen W.,Guo, H.,McGeary, Sean E.,Rodriguez-Mias, Ricard A.,Shin, C.,Baek, D.,Hsu, S.h.,Ghoshal, K.,Villen, J.,Bartel, David P. Cell Press 2014 Molecular cell Vol.56 No.1
MicroRNAs (miRNAs) regulate target mRNAs through a combination of translational repression and mRNA destabilization, with mRNA destabilization dominating at steady state in the few contexts examined globally. Here, we extend the global steady-state measurements to additional mammalian contexts and find that regardless of the miRNA, cell type, growth condition, or translational state, mRNA destabilization explains most (66%→90%) miRNA-mediated repression. We also determine the relative dynamics of translational repression and mRNA destabilization for endogenous mRNAs as a miRNA is induced. Although translational repression occurs rapidly, its effect is relatively weak, such that by the time consequential repression ensues, the effect of mRNA destabilization dominates. These results imply that consequential miRNA-mediated repression is largely irreversible and provide other insights into the nature of miRNA-mediated regulation. They also simplify future studies, dramatically extending the known contexts and time points for which monitoring mRNA changes captures most of the direct miRNA effects.
Disruption of Stamp/Ttll5 Gene in Male Mice Causes Sperm Malformation and Infertility
Geun-Shik Lee,Yuanzheng He,Edward J. Dougherty,Maria Jimenez-Movilla,Matteo Avella,Sean erullon,David S. Sharlin,Chunhua Guo,Smita Auasthi,Zhenhuan Zhang,Stephen P. Armstrong,Edra C. London,Weiping Ch 한국동물생명공학회(구 한국동물번식학회) 2012 발생공학 국제심포지엄 및 학술대회 Vol.2012 No.1