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- 저자 : Christoph Hein (검색결과 2 건)
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Christoph Hein,김낙수,홍석무,Joungsik Suh,Hartmut Hoffmann 한국자동차공학회 2008 International journal of automotive technology Vol.9 No.2
It is essential to develop efficient and cost-effective production methods to achieve or maintain international competitiveness. An innovative production method, such as rotary blanking, enables manufacturers to both reduce expenses and economize production time. However, there are not enough numerical analyses for this process. In this paper, numerical simulations of rotary blanking were performed. After comparing the cutting planes generated by conventional and rotary blanking experimental tests, the cutting areas of two punch geometries were analyzed. The influence of punch geometry on part quality was then investigated through simulations. The procedure for die stress analysis was established and stress distributions of the worksheet and the tools were analyzed. It is essential to develop efficient and cost-effective production methods to achieve or maintain international competitiveness. An innovative production method, such as rotary blanking, enables manufacturers to both reduce expenses and economize production time. However, there are not enough numerical analyses for this process. In this paper, numerical simulations of rotary blanking were performed. After comparing the cutting planes generated by conventional and rotary blanking experimental tests, the cutting areas of two punch geometries were analyzed. The influence of punch geometry on part quality was then investigated through simulations. The procedure for die stress analysis was established and stress distributions of the worksheet and the tools were analyzed.
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Growth in Infants with Cow's Milk Protein Allergy Fed an Amino Acid-Based Formula
Vandenplas, Yvan,Dupont, Christophe,Eigenmann, Philippe,Heine, Ralf G.,Host, Arne,Jarvi, Anette,Kuitunen, Mikael,Mukherjee, Rajat,Ribes-Koninckx, Carmen,Szajewska, Hania,Berg, Andrea von,Zhao, Zheng-Y The Korean Society of Pediatric Gastroenterology 2021 Pediatric gastroenterology, hepatology & nutrition Vol.24 No.4
Purpose: The present study assessed the role of an amino acid-based formula (AAF) in the growth of infants with cow's milk protein allergy (CMPA). Methods: Non-breastfed, term infants aged 0-6 months with symptoms suggestive of CMPA were recruited from 10 pediatric centers in China. After enrollment, infants were started on AAF for two weeks, followed by an open food challenge (OFC) with cow's milk-based formula (CMF). Infants with confirmed CMPA remained on AAF until 9 months of age, in conjunction with a cow's milk protein-free complementary diet. Body weight, length, and head circumference were measured at enrollment and 9 months of age. Measurements were converted to weight-for-age, length-for-age, and head circumference-for-age Z scores (WAZ, LAZ, HCAZ), based on the World Health Organization growth reference. Results: Of 254 infants (median age 16.1 weeks, 50.9% male), 218 (85.8%) were diagnosed with non-IgE-mediated CMPA, 33 (13.0%) tolerated CMF, and 3 (1.2%) did not complete the OFC. The mean WAZ decreased from 0.119 to -0.029 between birth and enrollment (p=0.067), with significant catch-up growth to 0.178 at 9 months of age (p=0.012) while being fed the AAF. There were no significant changes in LAZ (0.400 vs. 0.552; p=0.214) or HCAZ (-0.356 vs. -0.284; p=0.705) from the time of enrollment to age 9 months, suggesting normal linear and head growth velocity. Conclusion: The amino acid-based study formula, in conjunction with a cow's milk proteinfree complementary diet, supported normal growth till 9 months of age in a cohort of Chinese infants with challenge-confirmed non-IgE-mediated CMPA.
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